Zusammenfassung
Hintergrund
Die Strategien zur Diagnostik und Behandlung von Parotistumoren scheinen in den deutschen HNO-Kliniken teilweise äußerst unterschiedlich zu sein. Ziel dieser Arbeit war es, mittels einer deutschlandweiten Umfrage einen Überblick über den derzeitigen Stand zu gewinnen.
Material und Methoden
Allen deutschen HNO-Kliniken wurde postalisch ein standardisierter Fragebogen mit 19 Fragen zur Diagnostik und Behandlung von Parotistumoren zugesandt.
Ergebnisse
Die Gesamtrücksendequote betrug 128 von 170 versandten Fragebögen (75%). Es bestätigte sich die Annahme, dass Parotistumoren in deutschen HNO-Kliniken sehr uneinheitlich behandelt werden.
Schlussfolgerung
Auf der Grundlage der von uns erhobenen Daten und der ausstehenden Etablierung des klinischen Registers für Speicheldrüsenmalignome in Erlangen besteht Hoffnung, dass wichtige Fragen zur Behandlung von Speicheldrüsentumoren in naher Zukunft beantwortet werden können.
Abstract
Background
It seems that the choice of the treatment modalities for parotid gland tumors frequently depends on personal experience more than on evidence-based criteria. A nationwide survey was conducted to obtain an overview of current practice in German ENT hospitals.
Methods
A standardised questionnaire comprising 19 questions on the treatment and diagnostic methods for parotid gland tumors was sent to all ENT hospitals in Germany.
Results
The overall return rate of the questionnaires was 128 of 170 (75%). The results confirmed highly variable strategies for the treatment of parotid gland tumors in Germany.
Conclusion
On the basis of our survey and the upcoming establishment of a German database for salivary gland cancer in Erlangen, Germany, we hope to be able to clarify controversial topics on the treatment of parotid gland tumors in the near future.
Literatur
Al-Khafaji BM, Nestok BR, Katz RL (1998) Fine-needle aspiration of 154 parotid masses with histologic correlation. Cancer 84: 153–159
Armstrong JG, Harrison LB, Thaler HT et al. (1992) The indications for elective treatment of the neck in cancer of the major salivary glands. Cancer 69(3): 615–619
Bjordal K, Kaasa S, Mastekaasa A (1994) Quality of life in patients treated for head and neck cancer: a follow-up study 7 to 11 years after radiotherapy. Int J Radiat Oncol Biol Phys 28(4): 847–856
Bruneton JN, Mourou MY (1993) Ultrasound in salivary gland disease. ORL J Otorhinolaryngol Relat Spec 55: 284–289
Byrne MN, Spector JG, Garvin CF, Gado MH (1989) Preoperative assessment of parotid masses: a comparative evaluation of radiologic techniques to histopathologic diagnosis. Laryngoscope 99(3): 284–292
Chambers MS, Garden AS, Kies MS, Martin JW (2004) Radiation-induced xerostomia in patients with head and neck cancer: pathogenesis, impact on quality of life, and management. Head Neck 26(9): 796–807
Chilla R, Schneider K, Droese M (1986) Recurrence tendency and malignant transformation of pleomorphic adenomas. HNO 34(11): 467–469
Chummun S, McLean NR, Kelly CG et al. (2001) Adenoid cystic carcinoma of the head and neck. Br J Plast Surg 54(6): 476–480
Cohen EG, Patel SG, Lin O et al. (2004) Fine-needle aspiration biopsy of salivary gland lesions in a selected patient population. Arch Otolaryngol Head Neck Surg 130(6): 773–778
Cristallini EG, Ascani S, Farabi R et al. (1997) Fine-needle aspiration biopsy of salivary gland, 1985–1995. Acta Cytol 41: 1421–1425
Drobik C, Laskawi R, Schwab S (1995) Therapy of Frey syndrome with botulinum toxin A. Experiences with a new method of treatment. HNO 43(11): 644–648
Eckardt A, Kuettner C (2003) Treatment of gustatory sweating (Frey’s syndrome) with botulinum toxin A. Head Neck 25(8): 624–628
Federspil PA, Federspil P, Schatzle W (1994) Pleomorphic parotid adenomas and their recurrence. HNO 42(1): 28–35
Freling NJ, Molenaar WM, Vermey A et al. (1992) Malignant parotid tumors: clinical use of MR imaging and histologic correlation. Radiology 185(3): 691–696
Garden AS, el-Naggar AK, Morrison WH et al. (1997) Postoperative radiotherapy for malignant tumors of the parotid gland. Int J Radiat Oncol Biol Phys 37(1): 79–85
Gritzmann N, Rettenbacher T, Hollerweger A, Macheiner P (2003) Hubner of the salivary glands. Eur Radiol 13(5): 964–975; Epub 2002 Sep 5.
Guntinas-Lichius O (2003) Management of Frey’s syndrome and hypersialorrhea with botulinum toxin. Facial Plast Surg Clin North Am 11(4): 503–513
Guntinas-Lichius O (2004) The facial nerve in the presence of a head and neck neoplasm: assessment and outcome after surgical management. Curr Opin Otolaryngol Head Neck Surg 12(2): 133–141
Guntinas-Lichius O, Kick C, Klussmann JP et al. (2004) Pleomorphic adenoma of the parotid gland: a 13-year experience of consequent management by lateral or total parotidectomy. Eur Arch Otorhinolaryngol 261(3): 143–146. Epub 2003 Jul 22
Guntinas-Lichius O, Klussmann JP, Schroeder U et al. (2004) Primary parotid malignoma surgery in patients with normal preoperative facial nerve function: outcome and long-term postoperative facial nerve function. Laryngoscope 114(5): 949–956
Hoffman HT, Karnell LH, Robinson RA et al. (1999) National Cancer Data Base report on cancer of the head and neck: acinic cell carcinoma. Head Neck 21(4): 297–309
Howlett DC, Kesse KW, Hughes DV, Sallomi DF (2002) The E. Sonography role of imaging in the evaluation of parotid disease. Clin Radio 57(8): 692–701
Kelley D, Spiro RH (1996) Management of the neck in parotid carcinoma. Am J Surg 172: 695–697
Lang S, Rotter N, Lorenzen A et al. (2005) Salivary gland carcinomas Part II. Diagnosis and therapy. HNO 53(10): 905–913
Lang S, Rotter N, Lorenzen A et al. (2005) Salivary gland carcinomas Part 1. Epidemiology, etiology, malignancy criteria, prognostic parameters and classification HNO 53(9): 817–826; quiz 827–828
Leverstein H, Van der Wal JE, Tiwari RM et al. (1997) Results of the surgical management and histopathological evaluation of 88 parotid gland Warthin’s tumours. Clin Otolaryngol Allied Sci 22(6): 500–503
McGuirt WF (1989) Management of occult metastatic disease from salivary gland neoplasms. Arch Otolaryngol Head Neck Surg 115: 322–325
Pires FR, de Almeida OP, de Araujo VC, Kowalski LP (2004) Prognostic factors in head and neck mucoepidermoid carcinoma. Arch Otolaryngol Head Neck Surg 130(2): 174–180
Przewozny T, Stankiewicz C, Narozny W, Kuczkowski J (2004) Warthin’s tumor of the parotid gland. Epidemiological and clinical analysis of 127 cases. Otolaryngol Pol 58(3): 583–592
Rodriguez-Cuevas S, Labastida L, Baena L et al. (1995) Risk of nodal metastases from malignant salivary gland tumors related to tumor size and grade of malignancy. Eur Arch Otorhinolaryngol 252: 139–142
Rohrbach S, Laskawi R (2004) Botulinum toxin in otorhinolaryngology. HNO 52(7): 635–641
Sachse F, August C, Alberty J (2005) Malignant fibrous histiocytoma in the parotid gland Case series and literature review. HNO 13; [Epub ahead of print]
Schoengen A, Binder T, Krause HR et al. (1995) The value of fine needle aspiration cytology in suspected neoplastic salivary gland enlargement. HNO 43(4): 239–243
Seethala RR, LiVolsi VA, Baloch ZW (2005) Relative accuracy of fine-needle aspiration and frozen section in the diagnosis of lesions of the parotid gland. Head Neck 27(3): 217–223
Smith Frable MA, Frable WJ (1991) Fine-needle aspiration biopsy of salivary glands. Laryngoscope 101: 245–249
Spiro RH (1997) Distant metastasis in adenoid cystic carcinoma of salivary origin. Am J Surg 174(5): 495–498
Stanley MW (2002) Selected problems in fine needle aspiration of head and neck masses. Mod Pathol 15(3): 342–350
Stennert E, Guntinas-Lichius O, Klussmann JP, Arnold G (2001) Histopathology of pleomorphic adenoma in the parotid gland: a prospective unselected series of 100 cases. Laryngoscope 111(12): 2195–2200
Stennert E, Kisner D, Jungehuelsing M et al. (2003) High incidence of lymph node metastasis in major salivary gland cancer. Arch Otolaryngol Head Neck Surg 129(7): 720–723
Stewart CJ, MacKenzie K, McGarry GW, Mowat A (2000) Fine-needle aspiration cytology of salivary gland: a review of 341 cases. Diagn Cytopathol 22(3): 139–146
Sung MW, Kim KH, Kim JW et al. (2003) Clinicopathologic predictors and impact of distant metastasis from adenoid cystic carcinoma of the head and neck. Arch Otolaryngol Head Neck Surg 129(11): 1193–1197
Terhaard CH, Lubsen H, Rasch CR et al. (2005) The role of radiotherapy in the treatment of malignant salivary gland tumors. Int J Radiat Oncol Biol Phys 61(1): 103–111
Terhaard CH, Lubsen H, Van der Tweel I et al. (2004) S alivary gland carcinoma: independent prognostic factors for locoregional control, distant metastases, and overall survival: results of the Dutch head and neck oncology cooperative group. Head Neck 26(8): 681–692; discussion 692–693
Terrell JE, Kileny PR, Yian C et al. (1997) Clinical outcome of continuous facial nerve monitoring during primary parotidectomy. Arch Otolaryngol Head Neck Surg 123(10): 1081–1087
Teymoortash A, Werner JA (2002) Value of neck dissection in patients with cancer of the parotid gland and a clinical NO neck. Onkologie 25(2):122–126
Witt RL (1998) Facial nerve monitoring in parotid surgery: the standard of care? Otolaryngol Head Neck Surg 119(5): 468–470
Witt RL (2002) The significance of the margin in parotid surgery for pleomorphic adenoma. Laryngoscope 112(12): 2141–2154
Witten J, Hybert F, Hansen HS (1990) Treatment of malignant tumors in the parotid glands. Cancer 65: 2515–2520
Wolf SR, Schneider W, Suchy B, Eichhorn B (1995) Intraoperative facial nerve monitoring in parotid surgery. HNO 43(5): 294–298
Yu GY, Ma DQ, Zhang Y et al. (2004) Multiple primary tumours of the parotid gland. Int J Oral Maxillofac Surg 33(6): 531–534
Zbaren P, Schar C, Hotz MA, Loosli H (2001) Value of fine-needle aspiration cytology of parotid gland masses. Laryngoscope 111(11 Pt 1): 1989–1992
Zbaren P, Schupbach J, Nuyens M, Stauffer E (2005) Elective neck dissection versus observation in primary parotid carcinoma. Otolaryngol Head Neck Surg 132(3): 387–391
Zbaren P, Tschumi I, Nuyens M, Stauffer E (2005) Recurrent pleomorphic adenoma of the parotid gland. Am J Surg 189(2): 203–207
Danksagung
Wir danken allen teilnehmenden Kliniken für ihre Mitarbeit und Frau Dr. Inga Carolin Haas für die wertvolle Hilfe bei der Erstellung des Manuskriptes.
Interessenkonflikt
Es besteht kein Interessenkonflikt. Der korrespondierende Autor versichert, dass keine Verbindungen mit einer Firma, deren Produkt in dem Artikel genannt ist, oder einer Firma, die ein Konkurrenzprodukt vertreibt, bestehen. Die Präsentation des Themas ist unabhängig und die Darstellung der Inhalte produktneutral.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Preuss, S.F., Guntinas-Lichius, O. Zur Diagnostik und Behandlung von Parotistumoren. HNO 54, 868–874 (2006). https://doi.org/10.1007/s00106-006-1394-7
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00106-006-1394-7