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Morbus Parkinson

Perioperatives Management und Anästhesie

Parkinson’s disease

Perioperative management and anesthesia

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Zusammenfassung

In Deutschland werden jährlich etwa 10.000–15.000 M.-Parkinson(MP)-Patienten operiert. Mit dem demografisch bedingten Anstieg geriatrischer Patienten wird die Prävalenz des MP im chirurgischen Krankheitsgut weiterzunehmen. Diese Patienten haben ein erhöhtes Morbiditätsrisiko im Rahmen der perioperativen Behandlung, bedürfen häufiger intensivmedizinischer Betreuung und besonderer anästhesiologischer Aufmerksamkeit bei der Wahl der Medikamente. Eine sorgfältige präoperative Bewertung aller Begleiterkrankungen, die Aufrechterhaltung der oralen medikamentösen M.-Parkinson-Therapie bis unmittelbar vor dem geplanten Eingriff und eine kontinuierliche perioperative dopaminerge Therapie sind Schlüsselfaktoren für die Verringerung der postoperativen Morbidität.

Abstract

Approximately 10,000–15,000 Parkinson’s disease (PD) patients per year undergo surgery in Germany. The demographic developments along with further surgical progress and procedural refinements will lead to increasing numbers of PD patients in the operating theatre (OR). There are several perioperative risk factors for PD patients, they more often require prolonged intensive care treatment and warrant particular anesthesiological attention with regard to the choice of drugs and equipment. Careful evaluation of concomitant diseases, maintenance of oral Parkinson therapeutic drugs up to the time of surgery and continuous perioperative dopaminergic therapy are key factors for reducing postoperative morbidity in PD patients undergoing surgery.

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Interessenkonflikt

Der korrespondierende Autor weist auf folgende Beziehungen hin: U.W. served as consultant and lecturer and on advisory boards for Boehringer-Ingelheim, Glaxo-SmithKline, Lifescience KG, Novartis Pharmaceuticals, Orion Pharma, Schering AG, Schwarz-Pharma, Teva, UCB Pharma and received grant/research funding trom BMBF, DFG, NAF, Stiftung Doppelfeld, Stiftung Verum, dPV, Merck KGaA, Pharmacia & Upjohn.

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Authors and Affiliations

  1. Klinik und Poliklinik für Neurologie, Rheinische Friedrich-Wilhelms-Universität, DZNE – Deutsches Zentrum für Neurodegenerative Erkrankungen, Sigmund-Freud-Str. 25, 53105, Bonn, Deutschland

    U. Wüllner & O. Kaut

  2. Klinik und Poliklinik für Allgemein-, Viszeral-, Thorax- und Gefäßchirurgie, Rheinische Friedrich-Wilhelms-Universität, Bonn, Deutschland

    J. Standop

  3. Stereotaxie und MR-basierte Operationsverfahren, Klinik für Neurochirurgie, Rheinische Friedrich-Wilhelms-Universität, Bonn, Deutschland

    V. Coenen

  4. Klinik für Anästhesiologie und operative Intensivmedizin, Universitätsmedizin Mannheim, Mannheim, Deutschland

    A. Kalenka

  5. Klinik für Anästhesiologie und operative Intensivmedizin, Klinikum der Universität Witten/Herdecke, Kliniken der Stadt Köln gGmbH, Köln, Deutschland

    F. Wappler

Authors
  1. U. Wüllner
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  2. J. Standop
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  3. O. Kaut
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  4. V. Coenen
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  5. A. Kalenka
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  6. F. Wappler
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Corresponding author

Correspondence to U. Wüllner.

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Wüllner, U., Standop, J., Kaut, O. et al. Morbus Parkinson. Anaesthesist 61, 97–105 (2012). https://doi.org/10.1007/s00101-012-1992-6

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