Zusammenfassung
Die kontinuierliche Wundinfusion von Lokalanästhetika stellt ein Verfahren zur Reduktion postoperativer Schmerzen dar, das bisher überwiegend in der Orthopädie und in der Allgemeinchirurgie zum Einsatz kommt. Neben einer Reduktion des Schmerzniveaus konnte eine Verminderung des Opioidbedarfs gezeigt werden. Neueren Studien zufolge scheint dieses Verfahren darüber hinaus die Rehabilitation zu verbessern und auch den postoperativen Krankenhausaufenthalt zu verkürzen. Die kontinuierliche Wundinfusion von Lokalanästhetika ist eine einfach durchzuführende, effektive analgetische Maßnahme. Ein Vergleich mit anderen analgetischen Verfahren, wie z. B. peripheren Nervenblockaden, rückenmarknaher Epiduralanalgesie oder anderen multimodalen Analgesieverfahren, steht noch aus.
Abstract
Continuous wound infusion of local anesthetics, which is mainly used in general surgery and orthopedics, is an interesting technique in postoperative pain therapy. Continuous wound infusion of local anesthetics is able to reduce postoperative opioid requirements and results in decreased pain scores. Recent studies indicate that rehabilitation seems to be enhanced and postoperative hospital stay may be shorter. Continuous wound infusion is an effective analgesic technique, which is simple to perform. Comparisons with other analgesic techniques, such as peripheral nerve blocks, epidural analgesia and other multimodal analgesic concepts are still required.
Literatur
Ansaloni L, Agnoletti V, Bettini D et al (2007) The analgesic efficacy of continuous elastomeric pump ropivacaine wound instillation after appendectomy. J Clin Anesth 19:256–263
Apfelbaum JL, Chen C, Mehta SS, Gan TJ (2003) Postoperative pain experience: results from a national survey suggest postoperative pain continues to be undermanaged. Anesth Analg 97:534–540
Axelsson K, Nordenson U, Johanzon E et al (2003) Patient-controlled regional analgesia (PCRA) with ropivacaine after arthroscopic subacromial decompression. Acta Anaesthesiol Scand 47:993–1000
Baig MK, Zmora O, Derdemezi J et al (2006) Use of the ON-Q pain management system is associated with decreased postoperative analgesic requirement: double blind randomized placebo pilot study. J Am Coll Surg 202:297–305
Barber FA, Herbert MA (2002) The effectiveness of an anesthetic continuous-infusion device on postoperative pain control. Arthroscopy 18:76–81
Beaussier M, El’Ayoubi H, Rollin M et al (2009) Parietal analgesia decreases postoperative diaphragm dysfunction induced by abdominal surgery: a physiologic study. Reg Anesth Pain Med 34:393–397
Beaussier M, El’Ayoubi H, Schiffer E et al (2007) Continuous preperitoneal infusion of ropivacaine provides effective analgesia and accelerates recovery after colorectal surgery: a randomized, double-blind, placebo-controlled study. Anesthesiology 107:461–468
Bianconi M, Ferraro L, Ricci R et al (2004) The pharmacokinetics and efficacy of ropivacaine continuous wound instillation after spine fusion surgery. Anesth Analg 98:166–172
Bianconi M, Ferraro L, Traina GC et al (2003) Pharmacokinetics and efficacy of ropivacaine continuous wound instillation after joint replacement surgery. Br J Anaesth 91:830–835
Blumenthal S, Dullenkopf A, Rentsch K, Borgeat A (2005) Continuous infusion of ropivacaine for pain relief after iliac crest bone grafting for shoulder surgery. Anesthesiology 102:392–397
Borgeat A, Rawal N (2008) Wound catheter techniques for postoperative analgesia. A critical review of the literature, 1. Aufl. Darwin Grey Communications, Abingdon, S 120–121
Chen TF, Clarke N, Bowman R et al (1994) Intermuscular bupivacaine infusion for control of pain after renal surgery: a preliminary report. Br J Urol 74:155–159
Cheong WK, Seow-Choen F, Eu KW et al (2001) Randomized clinical trial of local bupivacaine perfusion versus parenteral morphine infusion for pain relief after laparotomy. Br J Surg 88:357–359
Chester JF, Ravindranath K, White BD et al (1989) Wound perfusion with bupivacaine: objective evidence for efficacy in postoperative pain relief. Ann R Coll Surg Engl 71:394–396
Essving P, Axelsson K, Kjellberg J et al (2009) Reduced hospital stay, morphine consumption, and pain intensity with local infiltration analgesia after unicompartmental knee arthroplasty. Acta Orthop 80:213–219
Forastiere E, Sofra M, Giannarelli D et al (2008) Effectiveness of continuous wound infusion of 0.5% ropivacaine by On-Q pain relief system for postoperative pain management after open nephrectomy. Br J Anaesth 101:841–847
Fredman B, Zohar E, Tarabykin A et al (2001) Bupivacaine wound instillation via an electronic patient-controlled analgesia device and a double-catheter system does not decrease postoperative pain or opioid requirements after major abdominal surgery. Anesth Analg 92:189–193
Gibbs P, Purushotham A, Auld C, Cuschieri RJ (1988) Continuous wound perfusion with bupivacaine for postoperative wound pain. Br J Surg 75:923–924
Gottschalk A, Burmeister MA, Radtke P et al (2003) Continuous wound infiltration with ropivacaine reduces pain and analgesic requirement after shoulder surgery. Anesth Analg 97:1086–1091
Hansen BP, Beck CL, Beck EP, Townsley RW (2007) Postarthroscopic glenohumeral chondrolysis. Am J Sports Med 35:1628–1634
Harvey GP, Chelly JE, AlSamsam T, Coupe K (2004) Patient-controlled ropivacaine analgesia after arthroscopic subacromial decompression. Arthroscopy 20:451–455
Johnson SM, Saint John BE, Dine AP (2008) Local anesthetics as antimicrobial agents: a review. Surg Infect (Larchmt) 9:205–213
Kerr DR, Kohan L (2008) Local infiltration analgesia: a technique for the control of acute postoperative pain following knee and hip surgery: a case study of 325 patients. Acta Orthop 79:174–183
Klein SM, Nielsen KC, Martin A et al (2001) Interscalene brachial plexus block with continuous intraarticular infusion of ropivacaine. Anesth Analg 93:601–605
Lau H, Patil NG, Lee F (2003) Randomized clinical trial of postoperative subfascial infusion with bupivacaine following ambulatory open mesh repair of inguinal hernia. Dig Surg 20:285–289
LeBlanc KA, Bellanger D, Rhynes VK, Hausmann M (2005) Evaluation of continuous infusion of 0.5% bupivacaine by elastomeric pump for postoperative pain management after open inguinal hernia repair. J Am Coll Surg 200:198–202
Levack ID, Holmes JD, Robertson GS (1986) Abdominal wound perfusion for the relief of postoperative pain. Br J Anaesth 58:615–619
Li J, Chen J, Kirsner R (2007) Pathophysiology of acute wound healing. Clin Dermatol 25:9–18
Morgan SJ, Jeray KJ, Saliman LH et al (2006) Continuous infusion of local anesthetic at iliac crest bone-graft sites for postoperative pain relief. A randomized, double-blind study. J Bone Joint Surg Am 88:2606–2612
Padmanabhan J, Rohatgi A, Niaz A et al (2007) Does rectus sheath infusion of bupivacaine reduce postoperative opioid requirement? Ann R Coll Surg Engl 89:229–232
Park JY, Lee GW, Kim Y, Yoo MJ (2002) The efficacy of continuous intrabursal infusion with morphine and bupivacaine for postoperative analgesia after subacromial arthroscopy. Reg Anesth Pain Med 27:145–149
Polglase AL, McMurrick PJ, Simpson PJ et al (2007) Continuous wound infusion of local anesthetic for the control of pain after elective abdominal colorectal surgery. Dis Colon Rectum 50:2158–2167
Sanchez B, Waxman K, Tatevossian R et al (2004) Local anesthetic infusion pumps improve postoperative pain after inguinal hernia repair: a randomized trial. Am Surg 70:1002–1006
Sandkuhler J (2002) Fear the pain. Lancet 360:426
Savoie FH, Field LD, Jenkins RN et al (2000) The pain control infusion pump for postoperative pain control in shoulder surgery. Arthroscopy 16:339–342
Schurr MJ, Gordon DB, Pellino TA, Scanlon TA (2004) Continuous local anesthetic infusion for pain management after outpatient inguinal herniorrhaphy. Surgery 136:761–769
Singh K, Samartzis D, Strom J et al (2005) A prospective, randomized, double-blind study evaluating the efficacy of postoperative continuous local anesthetic infusion at the iliac crest bone graft site after spinal arthrodesis. Spine (Phila Pa 1976) 30:2477–2483
Stewart A, Fan MM, Fong MJ et al (2004) Randomized trial of a pain control infusion pump following inguinal hernia repair. ANZ J Surg 74:873–876
Thomas DF, Lambert WG, Williams KL (1983) The direct perfusion of surgical wounds with local anaesthetic solution: an approach to postoperative pain? Ann R Coll Surg Engl 65:226–229
Toftdahl K, Nikolajsen L, Haraldsted V et al (2007) Comparison of peri- and intraarticular analgesia with femoral nerve block after total knee arthroplasty: a randomized clinical trial. Acta Orthop 78:172–179
Interessenkonflikt
Der korrespondierende Autor weist auf folgende Beziehungen hin: Herr PD Dr. André Gottschalk hat in den letzten Jahren Referentenhonorare der Firmen Baxter, B.Braun und MSD erhalten. Darüber hinaus war er Mitglied im Advisory Board der Fa. Baxter zum Thema „kontinuierliche Wundinfusion“.
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Gottschalk, A., Gottschalk, A. Kontinuierliche Wundinfusion von Lokalanästhetika. Anaesthesist 59, 1076–1082 (2010). https://doi.org/10.1007/s00101-010-1808-5
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DOI: https://doi.org/10.1007/s00101-010-1808-5