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The “Mini Brain” Sign in a Case of Vertebral Hemangioma Mimicking Solitary Plasmacytoma of the Spine

Refutal of a Pathognomonic Sign?

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References

  1. Shah BK, Saifuddin A, Price GJ. Magnetic resonance imaging of spinal plasmacytoma. Clin Radiol. 2000;55:439–45.

    Article  CAS  Google Scholar 

  2. Major NM, Helms CA, Richardson WJ. The “mini brain”: plasmacytoma in a vertebral body on MR imaging. AJR Am J Roentgenol. 2000;175:261–3.

    Article  CAS  Google Scholar 

  3. Alfalahi A, Khairi T, Albastaki U, Al Sibaie A, Rashid A, Attabib N, Raman L, Abedzadeh A, Ikbal S. Solitary bone plasmacytoma: the unusual case of extra-cranial mini brain. BJR Case Rep. 2018;4:20180065.

    Google Scholar 

  4. Zhang Z, Meng Q, Gao Z, Ma L. MR imaging features of solitary plasmacytoma of the spine. Clin Oncol Cancer Res. 2009;6:241–4.

    Article  Google Scholar 

  5. Kasliwal MK, O’Toole JE. Unique radiologic feature of spinal plasmacytoma: mini-brain appearance. Neurol India. 2011;59:486–7.

    Article  Google Scholar 

  6. Ferreira-Filho LA, Pedroso JL, Sato EA, Yared JH, Barsottini OG, Bulle Oliveira AS, Diniz-Ferreira NP. Teaching neuroimages: “mini brain” sign: a radiologic marker for vertebral solitary plasmacytoma. Neurology. 2014;82:e210–1.

    Article  Google Scholar 

  7. Gupta R, Mittal A, Mittal P, Kaur H, Sachdeva V, Mirchia K. Miniature brain in spine: the “mini brain sign” in vertebral plasmacytoma. Postgrad Med J. 2016;92:745–6.

    Article  Google Scholar 

  8. de Oliveira Sousa U, de Oliveira MF, Heringer LC, Rotta JM, Botelho RV. Sensitivity and specificity of “mini brain” image pattern to diagnose multiple myeloma and plasmacytoma. Coluna Columna. 2018;17:42–5.

    Article  Google Scholar 

  9. Doppman JL, Oldfield EH, Heiss JD. Symptomatic vertebral hemangiomas: treatment by means of direct intralesional injection of ethanol. Radiology. 2000;214:341–8.

    Article  CAS  Google Scholar 

  10. Cianfoni A, Massari F, Dani G, Lena JR, Rumboldt Z, Vandergrift WA, Bonaldi G. Percutaneous ethanol embolization and cement augmentation of aggressive vertebral hemangiomas at two adjacent vertebral levels. J Neuroradiol. 2013;41:269–74.

    Article  Google Scholar 

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Correspondence to Ding Zhang.

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D. Zhang, J.P. Andrade, J. Cassis and P. Soares declare that they have no competing interests.

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Zhang, D., Andrade, J.P., Cassis, J. et al. The “Mini Brain” Sign in a Case of Vertebral Hemangioma Mimicking Solitary Plasmacytoma of the Spine. Clin Neuroradiol 30, 173–175 (2020). https://doi.org/10.1007/s00062-019-00788-y

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