Abstract
Ketamine in a dose of 6 mg · kg−1 was nasally administered in 86 healthy children (ASA I and II), aged from two to five years undergoing elective general, urological or plastic surgery, 20 to 40 min before the scheduled surgery time. These children were compared with 62 others, also aged from two to five years, in whom promethazine and meperidine, 1 mg · kg−1 of each, were injected im. Sedation was started as excellent in 48 and as adequate in 19 children in the ketamine group, compared with nine and 12 respectively in Group 2 (P < 0.05), while salivation was similar in both groups. We conclude that nasal ketamine is an alternative to im preanaesthetic sedation administration in children aged from two to five years.
Résumé
Vingt à quarante minutes avant la chirurgie, de la kétamine 6 mg · kg−1 est administrée par voie nasale à 86 enfants en bonne santé (ASA I et II), âgés de deux à cinq ans programmés pour une intervention urologique ou plastique non urgente sous anesthésie générale. On compare ces enfants à 62 autres enfants du même âge, auxquels on a injecté par la voie i.m., soit de la mépéridine, soit de la prométhazine, à la dose de 1 mg · kg−1. La sédation est jugée excellente pour 48 et adéquate pour 19 des enfants du groupe kétamine, comparativement à 9 et 12 des enfants du groupe 2 (P < 0,05), alors que la salivation est identique dans les deux groupes. Nous en concluons que la kétamine nasale est une alternative a la prémédication intramusculaire pour des enfants de deux à cinq ans.
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Weksler, N., Ovadia, L., Muati, G. et al. Nasal ketamine for paediatric premedication. Can J Anaesth 40, 119–121 (1993). https://doi.org/10.1007/BF03011307
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DOI: https://doi.org/10.1007/BF03011307