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Anti-inflammatory activity of the major constituents ofLonicera japonica

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Abstract

Previously, we reported that then-butanol fraction ofLonicera japonica showed anti-inflammatrory activity in mice and rats. Several constituents such as loniceroside A and B, flavonoids and iridoids were isolated from this fraction. In this investigation, the anti-inflammatory activity of the major constituents ofL. japonica was studied. Loniceroside A, lonicerin and loganin showed anti-inflammatory activity comparable to aspirin.

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References Cited

  • Bhargava, K. P., Gupta, M. B., Gupta, G. P. and Mitra, C. R., Anti-inflammatory activity of saponins and other natural products.Indian J. Med. Res., 58, 724–730 (1970)

    PubMed  CAS  Google Scholar 

  • Kawai, H., Kutoyanagi, M. and Ueno, A., Iridoid glucosides fromLonicera japonica Thunb.Chem. Pharm. Bull., 36, 3664–3666 (1988)

    CAS  Google Scholar 

  • Kim, H. K., Namgoong, S. Y. and Kim, H. P., Anti-inflammatory activity of flavonoids: Mice ear edema inhibition.Arch. Pharm. Res., 16, 18–24 (1993)

    Article  CAS  Google Scholar 

  • Kubo, M., Matsuda, H., Tanaka, M., Nimura, Y., Okuda, H., Higashino, M., Tani, T., Namba, K. and Arichi, S., Studies on Scutellaria radix. VII. Anti-arthritic and anti-inflammatory actions of methanolic extract and flavonoid components from Scutellaria radix.Chem. Pharm. Bull., 32, 2724–2729 (1984)

    PubMed  CAS  Google Scholar 

  • Lee, S. J., Son, K. H., Chang, H. W., Kang, S. S., Park, P.-U., Kawk, W.-J., Han, C.-K. and Kim, H. P., Development of plant anti-inflammatory agents: Comparison of anti-inflammatory and analgesic activities of extracts fromLonicera japonica.Kor. J. Pharmacogn., 25, 363–367 (1994)

    Google Scholar 

  • Shanghai Science and Technologic Publisher and Shougakukan (1985) in The Dictionary of Chinese Drugs, Vol III, pp 2027–2029, Shougakukan, Tokyo.

    Google Scholar 

  • Son, K. H., Jung, K. Y., Chang, H. W., Kim, H. P. and Kang, S. S., Triterpenoid saponins from the aerial parts ofLonicera japonica.Phytochem., 35, 1005–1008 (1994a)

    Article  CAS  Google Scholar 

  • Son, K. H., Kim, J. S., Kang, S. S., Kim, H. P. and Chang, H. W., Isolation of flavonoids fromLonicera japonica.Kor. J. Pharmacogn., 25, 24–27 (1994b)

    CAS  Google Scholar 

  • Son, K. H., Park, I. O., Chung, K. C., Chang, H. W., Kim, H. P., Kim, J. S. and Kang, S. S., Flavonoids from the aerial parts ofLonicera japonica.Arch. Pharm. Res., 15, 365–370 (1992)

    Article  CAS  Google Scholar 

  • Tonnelli, G., Thiabault, L. and Ringler, I., A bioassay for the concomitent assessment of the antiphlogistic and thymolytic activities of topically applied corticoids.Endocrinol., 77, 625–634 (1965)

    Article  Google Scholar 

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Authors and Affiliations

  1. College of Pharmacy, Kangweon Nat'l. University, 200-701, Chuncheon, Korea

    Song Jin Lee & Hyun Pyo Kim

  2. Dept. Food Nutr., Andong Nat'l. University, 760-749, Andong, Korea

    Eun Joo Shin & Kun Ho Son

  3. College of Pharmacy, Yoengnam University, 712-749, Kyeongsan, Korea

    Hyeun Wook Chang

  4. Natural Products Res. Institute, Seoul Nat'l. University, 110-460, Seoul, Korea

    Sam Sik Kang

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  1. Song Jin Lee
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  2. Eun Joo Shin
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  3. Kun Ho Son
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  4. Hyeun Wook Chang
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  5. Sam Sik Kang
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Lee, S.J., Shin, E.J., Son, K.H. et al. Anti-inflammatory activity of the major constituents ofLonicera japonica . Arch. Pharm. Res. 18, 133–135 (1995). https://doi.org/10.1007/BF02979147

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  • DOI: https://doi.org/10.1007/BF02979147

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