Summary
Two methods are described for the detection of low concentrations of paraquat in biological fluids. A rapid spot test involves anin situ reaction on an SPE cartridge to form a vividly blue coloured radical ion. A quantitative method uses clean-up prior to oxidation to form the dipyridone derivative, which can be determined down to sub nanogram mL−1 levels using HPLC with fluorescence detection.
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References
Berry, D.J.; Grove, J.Clin Chim Acta 1971,34, 5–11.
Gill, R.; Moffat, A.C.J. Chromatogr. 1983,255, 483–490.
Levitt, T.Proc. Analyt Div Chem. Soc.Feb 1989, 72–76.
Woollen, B.H.; Mahler, J.D.Clin Chim Acta 1987,167, 225–229.
Tsuchihashi, H.; Tatsuno, M.; Otsuki, K.Kagaku Keisatsu Kenkyujo Hokoku Hokagaku-hen 1989,41, 269–271.
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Blake, D.K., Gallagher, R.T. & Woollen, B.H. Improved methods for the analysis of paraquat in biological fluids. Chromatographia 55 (Suppl 1), S183–S185 (2002). https://doi.org/10.1007/BF02493377
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DOI: https://doi.org/10.1007/BF02493377