Skip to main content
SpringerLink
Log in

Dysplastic gangliocytoma of cerebellum in a newborn

Diagnosis by ultrasonography and MRI

  • Originals
  • Published:
Pediatric Radiology Aims and scope Submit manuscript

Abstract

A cerebellar lesion was detected by ultrasonography (US) in a symptomatic newborn. Magnetic Resonance Imaging (MRI) demonstrated this lesion as a gyriform structure. Therefore a rare dysplastic gangliocytoma was suspected, which was compatible with histopathology. Immunohistochemical studies (monoclonal antibody Ki-67) showed signs of progression.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Lhermitte J, Duclos P (1920) Sur un ganglionerome diffus du cortex du cervelet. Bull Assoc Fr Etude Cancer 9: 99

    Google Scholar 

  2. Carter JE, Merren MD, Swann KW (1989) Preoperative diagnosis of Lhermitte-Duclos disease by magnetic resonance imaging: case report. J Neurosurg 70: 135

    PubMed  Google Scholar 

  3. Sabin HI, Lidov HG, Kendall BE, Symon L (1988) Lhermitte-Duclos disease (dysplastic gangliocytoma): a case report with CT and MRI. Acta Neurochir (Wien) 93: 149

    Article  Google Scholar 

  4. Brown WR, Angelo JN, Kelly DL (1980) Lhermitte-Duclos disease: case report with computerized tomographic scan. Neurosurgery 6: 189

    PubMed  Google Scholar 

  5. Carbone F, Brihaye J, Drochmans P (1955) Spongioblastome pariétooccipital et gangliocytome du cervelet chez le même malade. Acta Neurol Psychiatr Belg 55: 568

    PubMed  Google Scholar 

  6. Pritchett PS, Kind TI (1978) Dysplastic gangliocytoma of the cerebellum: an ultrastructural study. Acta Neuropathol (Berl) 41: 1

    Article  Google Scholar 

  7. Reeder RF, Saunders RL, Roberts DW, Fratkin JD, Cromwell LD (1988) Magnetic resonance imaging in the diagnosis and treatment of Lhermitte-Duclos disease (dysplastic gangliocytoma of the cerebellum) Neurosurgery 23: 240

    PubMed  Google Scholar 

  8. Reznik M, Schoenen J (1983) Lhermitte-Duclos disease. Acta Neuropathol (Berl) 59: 88

    Article  Google Scholar 

  9. Beuche W, Wickboldt J, Friede RL (1983) Lhermitte-Duclos disease: its minimal lesions in electron microscope data and CT findings. Clin Neuropathol 2: 163

    PubMed  Google Scholar 

  10. Roessmann U, Wongmongkolrit T (1984) Dysplastic gangliocytoma of cerebellum in a newborn: case report. J Neurosurg 60: 845

    PubMed  Google Scholar 

  11. Heitkamp JW, Rose JE (1983) Neck pain following migration of a ventriculocervical shunt. Surg Neurol 19: 285

    PubMed  Google Scholar 

  12. Probst A, Ulrich J, Zdrojewski B, Hirt HR (1979) Cerebellar ganglioglioma in a child. J Neuropathol Exp Neurol 38: 57

    PubMed  Google Scholar 

  13. Romiev J, Montoya F, Frerebeau C (1976) Tumeur hamartomateuse du cervelet évoquant le syndrome de Lhermitte et Duclos. Pédiatrie 31: 627

    Google Scholar 

  14. Milbouw G, Born JD, Martin D, Collignon J, Hans P, Reznik M, Bonnal J (1988) Clinical and radiological aspects of dysplastic gangliocytoma (Lhermitte-Duclos disease): a report of two cases with review of the literature. Neurosurgery 22: 124

    PubMed  Google Scholar 

  15. Ambler M, Pogacar S, Sidman R (1969) Lhermitte-Duclos disease (granule cell hypertrophy of the cerebellum): pathological analysis of the first familial cases. J Neuropathol Exp Neurol 28: 622

    PubMed  Google Scholar 

  16. Marano SR, Johnson PC, Spetzler RF (1988) Recurrent Lhermitte-Duclos disease in a child: case report. J Neurosurg 69: 599

    PubMed  Google Scholar 

  17. Lejeune JP, Blond S, Dupard T, Combelles G, Delandsheer JM (1987) Maladie de Lhermitte-Duclos: á propos d'une observation. Neurochirurgie 33: 408

    PubMed  Google Scholar 

  18. Schröder R, Bien K (1991) Proliferative activity of pilocytic astrocytomas: examination using the monoclonal antibody Ki-67. Adv Neurosurg 19: 176

    Google Scholar 

  19. Altman NR (1988) MR and CT characteristics of gangliocytoma: a rare cause of epilepsy in children. AJNR 9: 917

    PubMed  Google Scholar 

Download references

Author information

Author notes

  1. G. Benz-Bohm

    Present address: Department of Radiology, Pediatric Radiology, University of Cologne, Joseph-Stelzmann-Strasse 9, W-5000, Köln 41, FRG

Authors and Affiliations

  1. Department of Pathology, University of Cologne, Cologne, FRG

    R. Schröder

  2. Children's Hospital, University of Cologne, Cologne, FRG

    B. Widemann

  3. Department of Radiology, Pediatric Radiology, University of Cologne, Joseph-Stelzmann-Strasse 9, W-5000, Köln 41, FRG

    M. Dietlein

Authors
  1. M. Dietlein
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. R. Schröder
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. B. Widemann
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. G. Benz-Bohm
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Dietlein, M., Schröder, R., Widemann, B. et al. Dysplastic gangliocytoma of cerebellum in a newborn. Pediatr Radiol 22, 131–133 (1992). https://doi.org/10.1007/BF02011314

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02011314

Keywords

Search

Navigation