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Anti-phalloidine and anti-α-amanitine action of silybin in comparison with compounds similar to structural parts of silybin

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Summary

Silybin significantly antagonises the lethal poisoning of mice with α-amanitine or phalloidine. In the same test, taxifolin, coniferyl alcohol, fisetin and (+)-catechin were not effective.

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Authors and Affiliations

  1. Abteilungen für Pharmakologie und Analytik, Dr. Madaus & Co., Ostmerheimer Strasse 198, D-5000, Köln 91, Federal Republic of Germany

    W. Trost & G. Halbach

Authors
  1. W. Trost
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  2. G. Halbach
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Trost, W., Halbach, G. Anti-phalloidine and anti-α-amanitine action of silybin in comparison with compounds similar to structural parts of silybin. Experientia 34, 1051–1052 (1978). https://doi.org/10.1007/BF01915341

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