Skip to main content
Log in

Idiopathic recurrent pancreatitis

An approach to diagnosis and treatment

  • Original Articles
  • Published:
Digestive Diseases and Sciences Aims and scope Submit manuscript

Abstract

The cause of recurrent acute pancreatitis can be identified in the majority of patients. A small group of patients in whom an etiological association is not obvious is characterized as idiopathic recurrent pancreatitis (IRP). During the last seven years, we used endoscopic retrograde cholangiopancreatography (ERCP) and sphincter of Oddi (SO) manometric pressure studies to investigate 116 patients initially diagnosed as IRP. Forty-four of the 116 patients were found to have a demonstrable cause of their pancreatitis. Appropriate therapeutic intervention was carried out in 43 of these patients with a favorable outcome in the majority of patients noted during long-term follow-up.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Ransom JM: Etiological and prognostic factors in human acute pancreatitis: A review. Am J Gastroenterol 77:633–863, 1983

    Google Scholar 

  2. Soergel KH: Acute pancreatitis.In Gastrointestinal Disease, 2nd ed. Sleisenger and Fortran (eds). Philadelphia, WB Saunders, 1983, pp 1463–1985

    Google Scholar 

  3. Howard JM: Pancreatitis associated with gallstone.In Surgical Diseases of the Pancreas. JM Howard, GL Jordan (eds). Philadelphia, JB Lippincott, 1960; pp 169–189

    Google Scholar 

  4. Svensson JO, Norback B, Bokey EL, Edlund Y: Changing patterns in etiology of pancreatitis. Br J Surg 66:159–161, 1979

    PubMed  Google Scholar 

  5. Trapnell JE, Duncan EHL: Patterns of incidence in acute pancreatitis. Br Med J 2:179–182, 1975

    PubMed  Google Scholar 

  6. O'Sullivan JN, Nobrega FT, Morlock CG, et al: Acute and chronic pancreatitis in Rochester, Minnesota. Gastroenterology 3:373–379, 1972

    Google Scholar 

  7. Bar-Meir S, et al: Biliary and pancreatic duct pressures measured by ERCP manometry in patients with suspected papillary stenosis. Dig Dis Sci 24:209–213, 1979

    PubMed  Google Scholar 

  8. Geenen JE, Hogan WJ: Endoscopic access to the papilla of Vater. Endoscopy 12:47–59, 1980

    Google Scholar 

  9. Venu RP, Geenen JE, Hogan WJ et al: Idiopathic recurrent pancreatitis (IRP): Diagnostic role of ERCP and sphincter of Oddi manometry. Gastrointest Endosc 31(2):153, 1985

    Google Scholar 

  10. Geenen JE, Hogan WJ, Dodds WJ, et al: Intraluminal pressure recording from the human sphincter of Oddi. Gastroenterology 78:317–324, 1980

    PubMed  Google Scholar 

  11. Mallory A, Kern F Jr: Drug-induced pancreatitis: A critical review. Gastroenterology 78:813–820, 1980

    PubMed  Google Scholar 

  12. Northrup WF III, Simmons RL: Pancreatic trauma. Surgery 71:27–43, 1972

    PubMed  Google Scholar 

  13. Katon RM, Bilbao MR, Eidemiller LR, et al: Endoscopic retrograde cholangiopancreatography in the diagnosis and management of nonalcoholic pancreatitis. Surg Gynecol Obstet 147(3):333–338, 1978

    PubMed  Google Scholar 

  14. Cooperman M, Ferrara JJ, Carey LC, et al: Idiopathic acute pancreatitis: The value of endoscopic retrograde cholangiopancreatography. Surgery 90:666–670, 1981

    PubMed  Google Scholar 

  15. Feller ER: Endoscopic retrograde cholangiopancreatography in the diagnosis of unexplained pancreatitis. Arch Intern Med 144:1797–1799, 1984

    PubMed  Google Scholar 

  16. Hamilton I, Bradley P, Lintott DJ: Endoscopic retrograde cholangiopancreatography in the investigation and management of patients after acute pancreatitis. Br J Surg 69:504–506, 1982

    PubMed  Google Scholar 

  17. Cotton PB, Beales JSM: Endoscopic pancreatography in management of relapsing acute pancreatitis. Br Med J 1:608–611, 1974

    PubMed  Google Scholar 

  18. Ohmori K, Kiroshita H, Shiraha Y, et al: Pancreatic duct obstruction by a benign polypoid adenoma of the ampulla of Vater. Am J Surg 132:662–663, 1976

    PubMed  Google Scholar 

  19. Berk T, Friedman LS, Goldstein SD, et al: Relapsing acute pancreatitis as the presenting manifestation of an ampullary neoplasm in a patient with familial polyposis. Am J Gastroenterol 8:627–629, 1985

    Google Scholar 

  20. Venu RP, Geenen JE, Hogan WJ: Role of endoscopic retrograde cholangiopancreatography in the diagnosis and treatment of choledochocele. Gastroenterology 87:1144–1149, 1984

    PubMed  Google Scholar 

  21. Venu RP, Geenen JE, Stewart EG, et al: Endoscopic retrograde cholangiopancreatography: Diagnosis of cholelithiasis in patients with normal gallbladder x-rays and ultrasound studies. JAMA 249:758–761, 1983

    PubMed  Google Scholar 

  22. Opie EL: The etiology of acute hemorrhagic pancreatitis. Bull Johns Hopkins Hosp 12:182, 1901

    Google Scholar 

  23. Acosta JM, Ledesma CL: Gallstone migration as a cause of acute pancreatitis. N Engl J Med 290:484–487, 1974

    PubMed  Google Scholar 

  24. Acosta JM, Pellegrini CA, Skinner DB: Etiology and pathogenesis of acute biliary pancreatitis. Surgery 88:118–125, 1980

    PubMed  Google Scholar 

  25. Venu RP, Toouli J, Geenen JE, et al: Migrating common bile duct stones. Dig Dis Sci 26:949–953, 1981

    PubMed  Google Scholar 

  26. Goldberg PB, Long WB, Oleaga JA: Choledochocele as a cause of recurrent pancreatitis. Gastroenterology 78:1041–1045, 1980

    PubMed  Google Scholar 

  27. Cotton PB: Congenital anomaly of pancreas divisum as cause of obstructive pain and pancreatitis. Gut 21:105–114, 1980

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Venu, R.P., Geenen, J.E., Hogan, W. et al. Idiopathic recurrent pancreatitis. Digest Dis Sci 34, 56–60 (1989). https://doi.org/10.1007/BF01536154

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01536154

Key words

Navigation