Abstract
Eleven of our own cases of tuberous sclerosis with intraventricular tumor and 34 cases from the literature are reviewed. Initial symptoms and identification of tuberous sclerosis and tumor are reviewed. Results of surgical treatment, including direct radical excision and shunting are given. On gross examination, the tumor was most often loosely connected to ependyma near the foramen of Monro, causing hydrocephalus. Giant cell subependymal astrocytoma was frequently found on microscopic examination. The glial origin of the tumor is discussed and direct surgical approach of the tumor is proposed as the best treatment of these lesions.
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Boesel CP, Paulson GW, Kosnick EJ, Earle KM (1979) Brain hamartomas and tumors associated with tuberous sclerosis. Neurosurgery 4:410–417
Brown JM (1975) Tuberous sclerosis with malignant astrocytoma. Med J Aust 1:811–814
Carrier P (1981) Contribution à l'étude des localisations tumorales ventriculaires cérébrales de la sclérose tumétreuse de Bourneville. A propos de 7 observations. Thèse Médecine, Lyon I
Cooper JR (1971) Brain tumors in hereditary multiple system hamartomatosis (tuberous sclerosis). J Neurosurg 34:194–202
Fitz CR, Harwood-Nash DCF, Thompson JR (1974) Neuroradiology of tuberous sclerosis in children. Radiology 110:635–642
Globus JH, Strauss I, Selinsky H (1932) Das Neurospongioblastom, eine primäre Gehirngeschwulst bei disseminierter Neurospongioblastose (tuberose sklerose). Z Gesamte Neurol Psychiatr 140:1–29
Herz DA, Liebeskind A, Rosenthal A (1975) Cerebral angiographic changes associated with tuberous sclerosis. Radiology 115:647–649
Kapp JP, Paulson GW, Odom GL (1967) Brain tumors with tuberous sclerosis. J Neurosurg 26:191–202
Kessel FK (1949) Some radiological and neurosurgical aspects of tuberous sclerosis. Acta Psychiatr Neurol 24:499–522
Konishi Y, Ito M, Okuno T, Hojyo H (1978) Early clinical features and brain tumors in tuberous sclerosis. Ann Paedr Jpn 24:37–45
Lee BCP, Gawler J (1978) Tuberous sclerosis. Comparison of computed tomography and conventional neuroradiology. Radiology 127:403–407
Marty-Double C, Dememes D, Marty R (1976) Tumeur gliale intraventriculaire au cours de l'évolution d'une sclérose tubéreuse de Bourneville: étude intrastructurale. Ann Anat Pathol (Paris) 21:329–338
Monaghan HP, Krafchik BR, Macgregor DL, Fits CR (1981) Tuberous sclerosis complex in children. Am J Dis Child 135:912–917
Paillas JE, Pellegrin J, Vigouroux R, Serratrice G (1954) Tumeurs cérébrales au cours de la sclérose tubéreuse de Bourneville. Presse Med 62:1293–1296
Pampiglione G, Pugh E (1975) Infantile spasms and subsequent appearance of tuberous sclerosis syndrome. Lancet II:1046–1047
Puech P, Lereboullet J, Bernard P (1945) Sclérose tubéreuse et tumeurs cérébrales. Rev Neurol (Paris) 77:225–245
Reed WB, Nickel WR (1963) Internal manifestations of tuberous sclerosis. Arch Dermatol Syph (Chicago) 87:715–728
Rudnick PA, Hoshino N, Kitaoka T, Miura M (1961) Tuberous sclerosis complex and astrocytoma: report of a case with successful removal of the neoplasm. JAMA 178:73–75
Russel DS, Rubinstein LV (1971) Pathology of tumors of the nervous system. Williams & Wilkins, Baltimore, Md
Pellissier JF, Tripier MF, Berard-Badier M, Toga M (1972) Etude ultrastructurale de la tumeur du noyau caudé dans un cas de sclérose tubéreuse de Bourneville. Arch Anat Pathol 3:277–284
Poirier J, Escourolle R (1970) Etude ultrastructurale d'une tumeur cérébrale dans un cas de sclérose tubéreuse de Bourneville. IVe Congres International de Neuropathologie, 1970. Masson, Paris, pp 992–993
Ribaudeau Dumas JL, Poirier J, Escourolle R (1973) Etude ultra structurale des lesions cérébrales de la sclérose tubéreuse de Bourneville. Acta Neuropathol (Berl) 25:259–270
Sima AAF, Robertson DM (1979) Subependymal giant-cell astrocitoma: case report with ultrastructural study. J Neurosurg 50:240–245
Stender A, Sulch KJ (1943) Über die Ventrikeltumoren bei tuberoser Sklerose. Z Gesamte Neurol Psychiatr 176:556–578
Taptas JN, Kordiolis N, Charalambopoulos F (1978) Formes tumorales de la sclérose tubéreuse de Bourneville. Neurochirurgie 24:113–116
Toga M, Dubois D, Berard M, Tripier MF, Cesarini TP, Choux R (1969) Etude ultrastructurale de quatre cas de L.E. S.S. Acta Neuropathol (Berl) 14:1–13
Tsuchida T, Kamata K, Kawamata M, Okada K, Tanaka R, Oyake Y (1981) Brain tumors in tuberous sclerosis. Report of 4 cases. Child's Brain 8:271–283
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Frèrebeau, P., Benezech, J., Segnarbieux, F. et al. Intraventricular tumors in tuberous sclerosis. Child's Nerv Syst 1, 45–48 (1985). https://doi.org/10.1007/BF00706730
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DOI: https://doi.org/10.1007/BF00706730