Summary
The diurnal variation of 5′-nucleotidase activity in periportal and pericentral areas of rat liver parenchyma has been determined with quantitative histochemical means. 5′-Nucleotidase activity was estimated using microdensitometry in cryostat sections after being incubated with a medium according to Wachstein and Meisel (1957). It appeared that 5′-nucleotidase activity was significantly higher in pericentral areas than in periportal areas throughout the daily cycle and showed a maximum at the end of the light period. It was concluded that 5′-nucleotidase activity may be related with the capacity to diminish messenger RNA resulting in protein breakdown.
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Frederiks, W.M., Marx, F., Bosch, K.S. et al. Diurnal variation in 5′-nucleotidase activity in rat liver. Histochemistry 87, 439–443 (1987). https://doi.org/10.1007/BF00496815
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DOI: https://doi.org/10.1007/BF00496815