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Enterochromaffin cells as the endocrine source of gastrointestinal Substance P

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Summary

Immunoreactive Substance P is localized in the intramural neural plexuses of mammalian intestine, and in endocrine cells in the intestinal mucosa which have now been identified as enterochromaffin (EC). The presence of a neurotransmitter peptide in these cells favours the hypothesis of their neuroectodermal origin.

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Authors and Affiliations

  1. Department of Histochemistry, Royal Postgraduate Medical School, Hammersmith Hospital, W12 OHS, London, England

    Ph. Heitz, Julia M. Polak, Catherine M. Timson & A. G. E. Pearse

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  1. Ph. Heitz
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  2. Julia M. Polak
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  3. Catherine M. Timson
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  4. A. G. E. Pearse
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Additional information

On leave from the Department of Pathology, University of Basle; in receipt of a grant from the Swiss Academy of Medical Sciences

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Heitz, P., Polak, J.M., Timson, C.M. et al. Enterochromaffin cells as the endocrine source of gastrointestinal Substance P. Histochemistry 49, 343–347 (1976). https://doi.org/10.1007/BF00496138

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