Abstract
• Background
Adult-onset foveomacular vitelliform dystrophy (AOFVD) represents a heterogeneous group of disorders with different clinical, angiography, and histopathological features. The most common form is characterized by a yellow, round to oval subretinal macular lesion with or without central pigmented spot.
• Methods
Eight patients affected by typical AOFVD underwent fluorescein an giography and indocyanine green videoangiography (ICGV).
• Results
Fluorescein angiography showed a central hypofluorescent spot surrounded by an irregular hyperfluorescentring ICGV demonstrated a foveal nonfluorescent spot, visible during the entire examination, and a hyperfluorescent area surrounding the central spot, which became evident soon after the beginning of the examination.
• Conclusions
In light of previous histopathological studies, the central nonfluorescent spot may be interpreted as a masking effect of a pigment clump, whereas the hyper-fluorescent area may represent dye pooling or staining of the subretinal pigment epithelial material.
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Battaglia Parodi, M., Iustulin, D., Russo, D. et al. Adult-onset foveomacular vitelliform dystrophy and indocyanine green videoangiography. Graefe's Arch Clin Exp Ophthalmol 234, 208–211 (1996). https://doi.org/10.1007/BF00462035
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DOI: https://doi.org/10.1007/BF00462035