Summary
A 62-year-old woman developed subacute renal failure after the repeated administration of ifosfamide (IFX), despite its combination with continuous sodium 2-mercaptoethane sulfonate (mesna) infusion. Biopsy findings, the possible underlying mechanism, and the existing literature are discussed.
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Willemse, P.H.B., de Jong, P.E., Elema, J.B. et al. Severe renal failure following high-dose ifosfamide and mesna. Cancer Chemother. Pharmacol. 23, 329–330 (1989). https://doi.org/10.1007/BF00292414
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DOI: https://doi.org/10.1007/BF00292414