Abstract
It has recently been suggested that quality-of-life investigations should be included in the evaluation of new medical and surgical regimens. We present the quality-of-life evaluations for the first 40 consecutive patients undergoing laparoscopic antireflux surgery at our department. Two well-established and validated questionnaires, the Psychological General Well Being (PGWB) Index, and the Gastrointestinal Symptom Rating Scale (GSRS), were used. The PGWB gives a general measure of patients' well-being while the GSRS concentrates on gastrointestinal complaints. In untreated reflux esophagitis patients, the PGWB score is very low. We found normal PBWB scores preoperatively during optimal medical treatment with potent acid inhibition. The average score became significantly better (than on medical treatment, P<0.05) 1 month postoperatively, after which it fell off to normal values 3 and 8–12 months after operation. The GSRS scores were good in all subgroups postoperatively, especially regarding reflux syndrome, where scores were significantly (P<0.05) better than on medical treatment.
In conclusion: After laparoscopic antireflux surgery, patients had good quality-of-life scores, better than untreated patients and as good as or better than on optimal medical treatment. Different treatment regimens could be discriminated by adding the patients' view of the treatment effect. We suggest that quality-of-life effects should be included when evaluating new regimens in laparoscopic surgery.
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References
Behar J, Sheahan DG, Bianciani P, Spiro HM, Storer EH (1975) Medical and surgical management of reflux esophagitis. A 38-month report of a prospective clinical trial. N Engl J Med 293: 263–268
Croog SH, Levine S, Testa MA, Brown D, Bulpitt CJ, Jenkins CD, Klerman GL, Williams GH (1986) The effects of antihypertensive therapy on the quality of life. N Engl J Med 314: 1657–1664
DeMeester TR, Bonavina L, Albertucci M (1986) Nissen fundoplication for gastroesophageal reflux disease, evaluation of primary repair in 100 consecutive patients. Ann Surg 204: 9–20
Dimenäs E (1993) Methodological aspects of evaluation of quality of life in upper Gastrointestinal diseases. Scand J Gastroenterol 28(Suppl 199): 18–21
Dimenäs E, Glise H, Hallerbäck B, Hernkvist H, Svedlund J, Wiklund I (1993) Quality of life in patients with upper gastrointestinal symptoms: an improved evaluation of treatment regimens. Scand J Gastroenterol 28: 681–687
Dupuy HJ (1984) The physiological general well-being (PGWB) index. In: Wegner NK, Mattson ME, Furberg CF, Elinson J (eds) Assessment of quality of life in clinical trials of cardiovascular therapies. New York, Le Jacq Publishing, USA, pp 170–183
Gallup Poll (1989) UK attitudes to heartburn and reflux. Gallup Limited, October 1989
Glise H (1993) Quality of life assessments in patients with peptic ulcer during treatment and follow up. Scand J Gastroenterol 28(Suppl 199): 34–35
Glise H (1989) Healing, relapse rates and prophylaxis of reflux esophagitis. Scand J Gastroenterol 24(Suppl 156): 57–64
Glise H, Hallerbäck B (1993) Quality of life in gastrointestinal disease—reports from working groups and conclusions. Scand J Gastroenterol 28(Suppl 199): 47–49
Hallerbäck, B (1993) Assessment of quality of life among patients with suspected duodenal ulcer. Scand J Gastroenterol 28(Suppl 199): 32–33
Hallerbäck B, Unge P, Carling L, Edwin B, Glise H, Havu N, Lyrenäs E, Lundberg K (1994) Efficacy and safety of omeprazole 20 mg and 10 mg o.d. and ranitidine 150 mg b.i.d. in the long term treatment of reflux esophagitis. Gastroenterology, accepted for publication
Hetzel DJ, Dent J, Reed WD, Narelvala FM, Mackinnon M, McCarthy HJ, Mitchell B, Beveridge BR, Laurence BH, Gibson GG, Grant AK, Shearman DJC, Whitehead R, Buckle PJ (1989) Healing and relapse of severe reflux esophagitis after treatment with omeprazole. Gastroenterology 95: 903–912
Joelsson B, Johnsson F (1989) Heartburn—the acid test. Gut 30: 1523–1525
Johnsen R, Bernersen B, Straume B, Forde OH, Bostad L, Burhol PG (1991) Prevalences of endoscopic and histological findings in subjects with and without dyspepsia. Br Med J 302: 749–752
Johansson KE, Tibbling L. (1986) Maintenance treatment with ranitidine compared with fundoplication in gastroesophageal reflux disease. Scand J Gastroenterol 21: 779–788
Johansson J, Johnsson F, Joelsson B, Florén CH, Walter B (1993) Outcome five years after 360° fundoplication for gastroesofageal reflux disease. Br J Surg 80: 46–49
Lundell LR, Myers JC, Jaimeson GG (1994) Delayed gastric emptying and its relationship to symptoms of gas float after antireflux surgery. Eur J Surg 160: 161–166
Nebel OT, Fornes MF, Castell DO (1976) Symptomatic gastroesophageal reflux incidence and precipitating factors. Am J Dig Dis 21: 953–956
Perissat J, Collet D, Belliard R, Desplantez J, Magne E (1990) Laparoscopic cholecystectomy: the state of the art. A report on 700 consecutive cases. World J Surg 16: 1074–1082
Schindlbeck NE, Klauser AG, Berghammer G, Londong W, Muller-Lissner SA (1992) Three year follow up of patients with gastroesophageal reflux disease. Gut 33: 1016–1019
Spechler S (1992) Comparison of medical and surgical therapy for complicated gastroesophageal reflux disease in veterans. N Engl J Med 326: 786–792
Swanstrom L, Wayne R (1994) Spectrum of gastrointestinal symptoms after laparoscopic fundoplication. Am J Surg 167: 538–541
Svedlund J, Sjödin I, Dotervall G (1988) GSRS—A clinical rating scale for gastrointestinal symptoms in patients with irritable bowel syndrome and peptic ulcer disease. Dig Dis Sci 33: 129–134
Clinton B. Health Security Act (1993) New pricing criteria. HR 3600/S 1757. SCRIPT No. 1880, Dec 10, p 13
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Glise, H., Hallerbäck, B. & Johansson, B. Quality-of-life assessments in evaluation of laparoscopic Rosetti fundoplication. Surg Endosc 9, 183–189 (1995). https://doi.org/10.1007/BF00191963
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DOI: https://doi.org/10.1007/BF00191963