Summary
Over 10 years, 842 consecutive autopsies on patients dying from a malignant neoplasm were evaluated microscopically to determine the incidence of spinal and skeletal metastases. Vertebral wedging, sclerosis and areas of osteolysis were defined as features of spinal metastases. The incidence was 30.6%, 65% of which arose from lung, breast or lymphoma and myeloma. The frequency of extraspinal metastases was 9.8% with 66% arising from the lung, liver, lymphoma or myeloma; they were mainly situated in the ribs, skull and clavicle.
Résumé
Une révision de 842 autopsies de patients décédés par maladie cancéreuse sur une période de 10 ans est rapportée. L'étude microscopique a eu pour but de déterminer le taux de métastases vertébrales et de métastases osseuses extravertébrales. Un repérage macroscopique des lésions de tassements, de sclérose ou de géode, a permis l'étude histologique pour affirmer la métastase. L'incidence des métastases vertébrales est de 30,6% avec une tumeur primitive qui était dans 65% des cas localisée au poumon, au sein ou entrant dans le cadre d'une hémopathie maligne (lymphome et myélome). La fréquence des métastases osseuses extra-vertébrales était de 9,8% avec dans près de 66% des cas, une tumeur primitive localisée aupoumon, au foie ou entrant dans le cadre d'une hémopathie maligne. Les lésions étaient principalement au niveu des côtes, du crâne et de la clavicule.
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Ortiz Gómez, J.A. The incidence of vertebral body metastases. International Orthopaedics 19, 309–311 (1995). https://doi.org/10.1007/BF00181116
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DOI: https://doi.org/10.1007/BF00181116