Abstract
Why use radiation in the liver at all since it is known to be much more sensitive to radiation damage than the tumors growing in it? This is an excellent and oft-stated question by many in oncology. With the development of internal brachytherapy, the delivery of tumoricidal doses of radiation to tumors of all origins and in all segments of the liver became a reality. Recent advances in medical oncology (anti-angiogenic agents, new systemic chemotherapy agents) have produced encouraging response rates and increased median survivals for many solid tumors. However, despite clearance of disease elsewhere in the body, the liver is usually the site of tumor resistance and ultimately the patient’s death. Moreover, with increased skill and more sophisticated and specialized catheters, today’s interventional radiologists are able to help oncology patients more than ever before. Precise access to the particular artery feeding a chemoinsensitive or unresectable tumor is now a widely available service in most medical centers that treat cancer patients.
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Kennedy, A.S., Dezarn, W.A., McNeillie, P. (2008). 90Y Microspheres: Concepts and Principles. In: Bilbao, J.I., Reiser, M.F. (eds) Liver Radioembolization with 90Y Microspheres. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-35423-9_1
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DOI: https://doi.org/10.1007/978-3-540-35423-9_1
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