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Mechanisms in the Pathogenesis of Congenital Cardiac Malformations

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The Genetics of Cardiovascular Disease

Abstract

Human congenital cardiac malformations are traditionally classified by their anatomic characteristics. Ventricular septal defect, pulmonary valve stenosis, and atrial septal defect are all described according to the location of the abnormalities in the heart. While such a listing is important for physicians and surgeons who treat children with these malformations, a solely anatomic classification may obscure physiologic relationships important for identification of pathogenesis or etiology.

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Authors
  1. Edward B. Clark
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Editors and Affiliations

  1. Department of Pediatrics Institute of Human Genetics, University of Minnesota Hospital and Variety Club Children’s Hospital, Box 94, 420 Delaware Street, S.E., Minneapolis, MN, 55455, USA

    Mary Ella Mascia Pierpont M.D., Ph.D. (Assistant Professor of Pediatrics and Genetics) (Assistant Professor of Pediatrics and Genetics)

  2. Department of Pediatrics, University of Minnesota Hospital and Variety Club Children’s Hospital, Box 288, 420 Delaware Street, S.E., Minneapolis, MN, 55455, USA

    James H. Moller M.D. (Professor of Pediatrics, Dwan Professor in Education in Pediatric Cardiology) (Professor of Pediatrics, Dwan Professor in Education in Pediatric Cardiology)

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© 1987 Martinus Nijhoff Publishing, Boston

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Clark, E.B. (1987). Mechanisms in the Pathogenesis of Congenital Cardiac Malformations. In: Pierpont, M.E.M., Moller, J.H. (eds) The Genetics of Cardiovascular Disease. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2305-1_1

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  • DOI: https://doi.org/10.1007/978-1-4613-2305-1_1

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9419-1

  • Online ISBN: 978-1-4613-2305-1

  • eBook Packages: Springer Book Archive

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