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Immunopathology of Tuberculosis

  • Chapter
Molecular Pathology of Lung Diseases

Part of the book series: Molecular Pathology Library ((MPLB,volume 1))

Abstract

Tuberculosis remains one of the world’s leading infectious causes of death. According to the World Health Organization, the disease is currently spreading at the rate of one person per second. Tuberculosis is a contagious bacterial disease primarily involving the lungs, which develops after inhalation of infected droplets released following a cough from someone infected with the Mycobacterium tuberculosis (M-TB) agent. One third of the world’s population is infected with M-TB, resulting annually in approximately 9 million new tuberculosis cases and approximately 2 million tuberculosis deaths. The virulence of the combination of tuberculosis and human immunodeficiency virus and the rise of multidrug-resistant organisms are ominous developments. In response to the challenge of resurgent disease, numerous investigators are using the best tools of modern science to combat the disease. Nevertheless, there are surprising gaps in our knowledge of tuberculosis, especially secondary tuberculosis, the form that produces most clinical illness and nearly all transmissions of infection.

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Author information

Authors and Affiliations

  1. Department of Pathology and Laboratory Medicine, University of Texas-Houston Medical School, Houston, TX, USA

    Jeffrey K. Actor PhD (Associate Professor), Robert L. Hunter Jr. MD, PhD (Professor and Chairman) & Chinnaswamy Jagannath PhD (Associate Professor)

Authors
  1. Jeffrey K. Actor PhD
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  2. Robert L. Hunter Jr. MD, PhD
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  3. Chinnaswamy Jagannath PhD
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Editor information

Editors and Affiliations

  1. Department of Pathology, Penn State Milton S. Hershey Medical Center, Hershey, PA, USA

    Dani S. Zander MD

  2. Institute of Pathology, Laboratories for Molecular Cytogenetics, Medical University of Graz, Graz, Austria

    Helmut H. Popper MD

  3. Department of Pathology, University of Texas Health Science Center, San Antonio, TX, USA

    Jaishree Jagirdar MD

  4. Weill Medical College of Cornell University, New York, NY

    Abida K. Haque MD

  5. Department of Pathology, San Jacinto Methodist Hospital, Baytown, TX, USA

    Abida K. Haque MD

  6. Pathology and Laboratory Medicine, Weill Medical College of Cornell University, New York, NY

    Philip T. Cagle MD  & Roberto Barrios MD  & 

  7. The Methodist Hospital, Houston, TX, USA

    Philip T. Cagle MD  & Roberto Barrios MD  & 

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Actor, J.K., Hunter, R.L., Jagannath, C. (2008). Immunopathology of Tuberculosis. In: Zander, D.S., Popper, H.H., Jagirdar, J., Haque, A.K., Cagle, P.T., Barrios, R. (eds) Molecular Pathology of Lung Diseases. Molecular Pathology Library, vol 1. Springer, New York, NY. https://doi.org/10.1007/978-0-387-72430-0_40

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  • DOI: https://doi.org/10.1007/978-0-387-72430-0_40

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