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Exercise training and depression and anxiety in musculoskeletal pain patients: a meta-analysis of randomized control trials

Bewegungstraining und Depressionen und Angstzustände bei Patienten mit muskuloskeletalen Schmerzen: eine Metaanalyse randomisierter Kontrollstudien

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Summary

Background

Depression and anxiety in patients with musculoskeletal pain harm health and exercise can be effective in improving the condition of these patients. This study was aimed at systematically reviewing and providing a meta-analysis of the effect of exercise training on improving depression and anxiety in patients with musculoskeletal pain.

Methods

The search was done in three databases including PubMed, the Cochrane Library, and Google Scholar up to August 2021. For each of the studies included in the meta-analysis, the mean, standard deviation, and sample size were extracted in the post-test, and the effect size was calculated. Publication bias and heterogeneity were assessed in studies at the end of the analysis.

Results

Nineteen randomized control trials were included in the meta-analysis. Exercise training has a positive effect on depression in patients with musculoskeletal pain, so exercise reduces depression and Hedges’ g was equal to −0.21, with confidence intervals of −0.40, −0.02. Exercise training has a positive effect on anxiety in patients with musculoskeletal pain, so exercise reduces anxiety and Hedges’ g was equal to −0.63, with confidence intervals of −1.08, −0.19.

Conclusions

It was found that exercise training is effective in improving depression and anxiety in patients with musculoskeletal pain and therefore this treatment should be given more attention from clinical specialists.

Zusammenfassung

Grundlagen

Depressionen und Angstzustände bei Patienten mit Schmerzen des muskuloskeletalen Systems beeinträchtigen die Gesundheit. Bewegung kann den Zustand dieser Patienten wirksam verbessern. Ziel dieser Studie war es, die Wirkung von Bewegungstraining auf die Verbesserung von Depressionen und Angstzuständen bei Patienten mit Schmerzen des Bewegungsapparats systematisch zu überprüfen und eine Metaanalyse zu erstellen.

Methodik

Die Suche erfolgte in drei Datenbanken (PubMed, Cochrane Library und Google Scholar) bis August 2021. Für jede der in die Metaanalyse eingeschlossenen Studien wurden im Posttest der Mittelwert, die Standardabweichung und die Stichprobengröße extrahiert sowie die Effektgröße berechnet. Am Ende der Analyse wurden Publikationsfehler und Heterogenität in den Studien bewertet.

Ergebnisse

In die Metaanalyse wurden 19 randomisierte Kontrollstudien einbezogen. Bewegungstraining hat einen positiven Effekt auf Depressionen bei Patienten mit muskuloskeletalen Schmerzen, d. h. Bewegung reduziert Depressionen (Hedgesʼ g = −0,21; Konfidenzintervall −0,40 bis −0,02). Bewegungstraining hat einen positiven Effekt auf die Angst von Patienten mit muskuloskeletalen Schmerzen, d. h. Bewegung reduziert die Angst (Hedgesʼ g = −0,63; Konfidenzintervall −1,08 bis −0,19).

Schlussfolgerungen

Es wurde festgestellt, dass Bewegungstraining Depressionen und Angstzustände bei Patienten mit muskuloskeletalen Schmerzen wirksam lindern kann, weshalb diese Behandlung von klinischen Spezialisten stärker berücksichtigt werden sollte.

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  1. Medicine, Quran and Hadith Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran

    Sohrab Amiri

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Amiri, S. Exercise training and depression and anxiety in musculoskeletal pain patients: a meta-analysis of randomized control trials. Neuropsychiatr 37, 88–100 (2023). https://doi.org/10.1007/s40211-022-00431-2

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