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Effect of Selenium Supplementation on Lipid Peroxidation, Antioxidant Enzymes, and Lactate Levels in Rats Immediately After Acute Swimming Exercise

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Abstract

The present study aims to evaluate the effect of selenium supplementation on lipid peroxidation and lactate levels in rats subjected to acute swimming exercise. Thirty-two adult male rats of Sprague–Dawley type were divided into four groups. Group 1, control; group 2, selenium-supplemented; group 3, swimming control; group 4, selenium-supplemented swimming group. The animals in groups 2 and 4 were supplemented with (i.p.) 6 mg/kg/day sodium selenite for 4 weeks. The blood samples taken from the animals by decapitation method were analyzed in terms of erythrocyte-reduced glutathione (GSH), serum glutathione peroxidase (GPx) and superoxide dismutase (SOD), and plasma malondialdehyde (MDA) and lactate using the colorimetric method, and serum selenium values using an atomic emission device. In the study, the highest MDA and lactate values were found in group 3, while the highest GSH, GPx and SOD values were obtained in group 4 (p < 0,001). Group 2 had the highest and group 3 had the lowest selenium levels (p < 0,001). Results of the study indicate that the increase in free radical production and lactate levels due to acute swimming exercise in rats might be offset by selenium supplementation. Selenium supplementation may be important in that it supports the antioxidant system in physical activity.

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Authors and Affiliations

  1. City Office of Youth Sport, 42040, Konya, Turkey

    Mustafa Akil

  2. School of Veterinary, Department of Food Hygene, Selcuk University, Konya, Turkey

    Umit Gurbuz

  3. School of Physical Education and Sports, Selçuk University, Konya, Turkey

    Mursel Bicer

  4. Selcuklu School of Medicine, Department of Biochemistry, Selçuk University, Konya, Turkey

    Abdullah Sivrikaya

  5. Meram School of Medicine, Department of Physiology, Selçuk University, Konya, Turkey

    Rasim Mogulkoc

  6. Selcuklu School of Medicine, Department of Physiology, Selçuk University, Konya, Turkey

    Abdulkerim Kasim Baltaci

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  1. Mustafa Akil
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  2. Umit Gurbuz
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  3. Mursel Bicer
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  4. Abdullah Sivrikaya
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  6. Abdulkerim Kasim Baltaci
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Correspondence to Mustafa Akil.

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Akil, M., Gurbuz, U., Bicer, M. et al. Effect of Selenium Supplementation on Lipid Peroxidation, Antioxidant Enzymes, and Lactate Levels in Rats Immediately After Acute Swimming Exercise. Biol Trace Elem Res 142, 651–659 (2011). https://doi.org/10.1007/s12011-010-8785-z

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  • DOI: https://doi.org/10.1007/s12011-010-8785-z

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