Zusammenfassung
Fragestellung
Die derzeitige Standardtherapie zur Behandlung der obstruktiven Schlafapnoe ist die CPAP-Therapie. Um einen Überblick über das Nutzungsverhalten der Patienten zu erhalten, wurden in Deutschland flächendeckend Therapiedaten aus dem CPAP-Gerät S8 (Fa. ResMed, Sydney, Australien) ausgelesen und ausgewertet.
Patienten und Methoden
Folgende Daten wurden retrospektiv von 4281 Patienten (Alter: 58,4±11,2 Jahre; 17,6% w., 82,4% m.) erhoben: Apnoe-Hypopnoe-Index (AHI), mittlerer Maskendruck, Maskendruck 95. Perzentil, mittlere Leckage, Leckage 95. Perzentil, Nutzungsdauer, Nutzungseffizienz (Nutzungstage/Gesamttage). Die Daten der letzten 156,7±25,0 Tage (Spanne: 30–180 Tage) wurden über eine Datenkarte aus dem CPAP-Gerät ausgelesen. Informationen über Maskentyp und Therapiedauer wurden ebenfalls ermittelt.
Ergebnisse
Die Therapiedauer betrug 3,5±3,6 Jahre, die maximale Therapiedauer lag bei 15,8 Jahren. Die Patienten nutzten das CPAP-Gerät an 6,4±1,4 Tagen/Woche. Die Anwendungszeit/Nacht betrug 6h 16 min ±1 h 34min. Die Adhärenz lag bei den Schwellenwerten 3 h/Nacht, 4 h/Nacht und 5 h/Nacht jeweils bei 97,0%, 91,8% und 79,9%. Der AHI lag bei 6,2±4,8/h, der mittlere Maskendruck bei 8,7±2,0 cmH2O und die mittlere Leckage bei 0,13±0,16 l/s. Das S8 wurde in 71,6% der Fälle im CPAP-Modus betrieben und in 28,4% im APAP-Modus.
Fazit
Im untersuchten Patientenkollektiv war die Therapieadhärenz sowohl im CPAP- als auch im APAP-Modus hoch und die Therapieeffektivität in beiden Modi gut.
Abstract
Aim of the study
CPAP (continuous positive airway pressure) is the therapy of choice for obstructive sleep apnea (OSA). In order to obtain an overview on CPAP adherence, therapy data from the CPAP device S8 (ResMed, Sydney, Australia) were obtained and evaluated.
Patients and Methods
The data of 4281patients (age 58.4±11.2 years; 17.6% female, 82.4% male) were retrospectively collected: apnea hypopnea index (AHI), mean mask pressure, mask pressure 95th percentile, mean leakage, leakage 95th percentile, duration of use, efficiency (days of use/total days). Data from the last 156.7±25.0 days (range 30–180 days) were obtained from the data card included in the CPAP device. Information on mask type and therapy duration were also determined.
Results
Therapy duration was 3.5±3.6 years, maximum therapy duration was 15.8 years. The patients used the CPAP device 6.4±1.4 days/week. Use/night was 6 h 16 min±1 h 34 min. Adherence was 97.0%, 91.8%, and 79.9% regarding the thresholds 3 h/night, 4 h/night and 5 h/night. The apnea−hypopnea index (AHI) was 6.2±4.8/h. Mean mask pressure was 8.7±2.0 cmH2O and mean leakage 0.13±0.16 l/s. The S8 was used in 71.6% of the cases in the CPAP mode and in 28.4% in the APAP mode.
Conclusion
Therapy adherence was high in both the APAP and CPAP modes. Furthermore, therapy efficiency was good.
Literatur
Hoffstein V (2007) Review of oral appliances for treatment of sleep-disordered breathing. Sleep Breath 11(1):1–20
Shahar E, Whitney CW, Redline S et al (2001) Sleep-disordered breathing and cardiovascular disease: cross-sectional results of the sleep heart health study. Am J Respir Crit Care Med 163(1):19–25
Mooe T, Franklin KA, Holmström K et al (2001) Sleep-disordered breathing and coronary artery disease: long-term prognosis. Am J Respir Crit Care Med 164(10 Pt 1):1910–1913
Engleman HM, Kingshott RN, Wraith PK et al (1999) Randomized placebo-controlled crossover trial of continuous positive airway pressure for mild sleep Apnea/Hypopnea syndrome. Am J Respir Crit Care Med 159(2):461–467
Massie CA, McArdle N, Hart RW et al (2003) Comparison between automatic and fixed positive airway pressure therapy in the home. Am J Respir Crit Care Med 167(1):20–23
Becker HF, Jerrentrup A, Ploch T et al (2003) Effect of nasal continuous positive airway pressure treatment on blood pressure in patients with obstructive sleep apnea. Circulation 107:68–73
Pepperell JC, Ramdassingh-Dow S, Crosthwaite N et al (2002) Ambulatory blood pressure after therapeutic and subtherapeutic nasal continuous positive airway pressure for obstructive sleep apnoea: a randomised parallel trial. Lancet 359:204–210
Orth M, Duchna HW, Kotterba S et al (2008) Langzeit-Compliance der CPAP-Therapie bei obstruktivem Schlafapnoe-Syndrom. Somnologie 12:258–269
Pepin JL, Leger P, Veale D et al (1995) Side effects of nasal continuous positive airway pressure in sleep apnea syndrome. Study of 193 patients in two French sleep centers. Chest 107:375–381
Krieger J, Kurtz D, Petiau C et al (1996) Long-term compliance with CPAP therapy in obstructive sleep apnea patients and in snorers. Sleep 19:136–143
Krieger J, Sforza E, Petiau C, Weiss T (1998) Simplified diagnostic procedure for obstructive sleep apnoea syndrome: lower subsequent compliance with CPAP. Eur Respir J 12:776–779
Mc Ardle N, Devereux G, Heidarnejad H et al (1999) Long-term use of CPAP therapy for sleep apnea / hypopnea syndrome. Am J Respir Crit Care Med 159:1108–1114
Wolkove N, Baltzan M, Kamel H et al (2008) Long-term compliance with continuous positive airway pressure in patients with obstructive sleep apnea. Can Respir J 15(7):365–369
Richard W, Venker J, Herder C den et al (2007) Acceptance and long-term compliance of nCPAP in obstructive sleep apnea. Eur Arch Otorhinolaryngol 264:1081–1086
Russo-Magno P, O’Brien A, Panciera T, Rounds S (2001) Compliance with CPAP therapy in older men with obstructive sleep apnea. JAGS 49:1205–1211
Sanders MH, Gruendl CA, Rogers RM (1986) Patient compliance with nasal CPAP therapy for sleep apnea. Chest 90:330–333
Sin DD, Mayers I, Man GCW, Pawluk L (2002) Long-term compliance rates to continuous positive airway pressure in obstructive sleep apnea: a populationbased study. Chest 121:430–435
Weaver TE, Grunstein RR (2008) Adherence to continuous positive airway pressure therapy: the challenge to effective treatment. Proc Am Thorac Soc 5(2):173–178
Noseda A, Jann E, Hoffmann G et al (2000) Compliance with nasal continuous positive airway pressure assessed with a pressure monitor: pattern of use and influence of sleep habits. Respir Med 94:76–81
Interessenkonflikt
Der korrespondierende Autor weist auf folgende Beziehung(en) hin: G. Weinreich ist sowohl Angestellter der Ruhrlandklinik als auch der Fa. ResMed. A. Graml und H. Woehrle sind Angestellte der Fa. ResMed.
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Woehrle, H., Graml, A. & Weinreich, G. Therapieadhärenz bei CPAP-Patienten. Somnologie 14, 135–139 (2010). https://doi.org/10.1007/s11818-010-0470-0
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DOI: https://doi.org/10.1007/s11818-010-0470-0