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Phylogenetic and recombination analysis of genomic sequences of PCV2 isolated in Korea

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Abstract

The complete genomic sequences of 13 PCV2 viruses obtained between 2005 and 2007 were analyzed in order to determine their phylogenetic relationship and identify possible recombination events between PCV2a and PCV2b. Twelve PCV2b viruses and one PCV2a virus were identified by phylogenetic analysis. Notably, two PCV2b viruses (PF163 and C7201-1) were shown to belong to the 1B subgroup of PCV2b, which had not been previously reported in Korea. Theses two viruses were also predicted to be possible recombinants between PCV2a (the minor parent) and PCV2b (the major parent) by the RDP program (P < 0.01). A recombination site was predicted to exist in ORF1 of both viruses. This additional evidence of PCV2 recombination in Korea further supports the important role of recombination in genetic evolution.

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Acknowledgment

This work was supported by a grant (Code# 20070401034009) from BioGreen 21 Program, Rural Development Administration, and by the Research Institute for Veterinary Science, Republic of Korea.

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Authors and Affiliations

  1. Department of Veterinary Virology, College of Veterinary Medicine and BK21 Program for Veterinary Science, Seoul National University, Seoul, 151-742, Korea

    Hye Kwon Kim, Yuzi Luo, Hyung Joon Moon, Seong Jun Park, Hyun Ok Keum, Semi Rho & Bong Kyun Park

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  1. Hye Kwon Kim
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  2. Yuzi Luo
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  3. Hyung Joon Moon
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  4. Seong Jun Park
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  5. Hyun Ok Keum
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  7. Bong Kyun Park
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Correspondence to Bong Kyun Park.

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Hye Kwon Kim and Yuzi Luo contributed equally to this work.

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Kim, H.K., Luo, Y., Moon, H.J. et al. Phylogenetic and recombination analysis of genomic sequences of PCV2 isolated in Korea. Virus Genes 39, 352–358 (2009). https://doi.org/10.1007/s11262-009-0395-5

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  • DOI: https://doi.org/10.1007/s11262-009-0395-5

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