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Alternative splicing and gene polymorphism of the human TAP3/SEC14L4 gene

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Abstract

Three closely related human SEC14p-like proteins (hTAP1, hTAP2, hTAP3, or SEC14L2, SEC14L3, SEC14L4, respectively) have been described that are related to the Saccharomyces cerevisiae SEC14 protein. These proteins may participate in intracellular lipid transport and influence regulatory lipid-dependent events. Here we report the isolation of an alternatively spliced hTAP3 cDNA and a polymorphism within the coding region of the hTAP3/SEC14L4 gene.

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Acknowledgments

This work was supported by the Swiss National Science Foundation.

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Author notes

  1. Jean-Marc Zingg

    Present address: Vascular Biology Laboratory, Office 621, JM USDA-Human Nutr. Res. Ctr. On Aging, Tufts University, 711 Washington St, Boston, MA, 02111, USA

Authors and Affiliations

  1. Department of Pediatric Endocrinology and Diabetology, University Children’s Hospital, Bern, Switzerland

    Petra Kempna

  2. Department of Experimental Medicine, University of Genoa, Genoa, Italy

    Roberta Ricciarelli

  3. Institute of Biochemistry and Molecular Medicine, Universität Bern University of Bern, Bühlstrasse 28, 3012, Bern, Switzerland

    Angelo Azzi & Jean-Marc Zingg

Authors
  1. Petra Kempna
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  2. Roberta Ricciarelli
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  3. Angelo Azzi
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  4. Jean-Marc Zingg
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Correspondence to Jean-Marc Zingg.

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Kempna, P., Ricciarelli, R., Azzi, A. et al. Alternative splicing and gene polymorphism of the human TAP3/SEC14L4 gene. Mol Biol Rep 37, 3503–3508 (2010). https://doi.org/10.1007/s11033-009-9943-2

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  • DOI: https://doi.org/10.1007/s11033-009-9943-2

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