Skip to main content
Log in

CT- und MRT-Befunde an isolierten Leichenherzen

Vergleich der radiologischen mit den pathologisch-anatomischen Befunden

Computed tomography and magnetic resonance imaging compared to pathoanatomic findings in isolated human autopsy hearts

  • Originalarbeit
  • Published:
Rechtsmedizin Aims and scope Submit manuscript

Zusammenfassung

An 34 isolierten Leichenherzen wurden Computertomographie- (CT-) und Magnetresonanztomographie- (MRT-) Befunde mit pathologisch-anatomischen Befunden und postmortalen Veränderungen verglichen. Innere Totenflecke und postmortale Gerinnselbildungen waren in der MRT, beginnende Fäulnis durch die Darstellung kleiner Gasblasen in der CT gut zu diagnostizieren. Kardiale Verkalkungen der Klappen, der Koronarien und der Papillarmuskeln konnten computertomographisch in ihrem Befallsmuster exakt lokalisiert werden. Ein Septuminfarkt zeigte sich sehr deutlich im T2-gewichteten MR-Bild. Die kollagenen Myokardnarbenareale konnten durch die von ihrer Zusammensetzung abhängigen Kontrastierungen in der T2-Wichtung veranschaulicht werden. Morphologische Veränderungen, wie Hypertrophie und Dilatation, waren sehr deutlich in ihrem Ausmaß auch in der postmortalen Bildgebung zu beurteilen. Die virtuell und real gemessenen Kammerwandstärken stimmten überein. Ein verkalkter Venenbypass mit Thrombosierung war erkennbar. Lediglich eine agonale intramurale Blutung fiel in der primären postmortalen radiologischen Diagnostik aufgrund nur sehr dezenter Kontraste nicht auf. Insgesamt zeigte sich eine sehr gute Übereinstimmung der radiologischen Befunde mit den histologisch bestätigten Sektionsdiagnosen.

Abstract

Computed tomography (CT) and magnetic resonance imaging (MRI) findings obtained from 34 isolated autopsy hearts were compared to pathoanatomic findings and postmortem changes. MRI clearly revealed internal postmortem lividity and postmortem blood clot formation, whereas small gas bubbles demonstrated by CT referred to beginning putrefaction. The pattern of cardiac calcification of the valves, the coronary vessels and papillary muscles could be exactly located by employing CT. The T2-weighted MR image clearly showed a septal infarction. Due to their composition-based contrast, collagenic myocardial scar areas could be demonstrated in T2 weighted images. Morphological changes, such as hypertrophy and dilatation, could be evaluated for both extent and postmortem pattern. The actual ventricular wall thicknesses were identical with those measured. A calcified venous bypass with thromboses was detected. Primary postmortem radiological diagnosis only failed in a case of agonal intramural bleeding which was not detectable due to highly discreet contrast. In general, the radiological findings obtained were in very good correspondence with the histologically confirmed autopsy diagnoses.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Abb. 1
Abb. 2
Abb. 3
Abb. 4
Abb. 5
Abb. 6
Abb. 7
Abb. 8

Literatur

  1. Achenbach S, Ropers D, Regenfus M, Pohle K, Giesler T, Moshage W, Daniel WG (2001) Noninvasive coronary angiography by magnetic resonance imaging, electron-beam computed tomography, and multislice computed tomography. Am J Cardiol 88:70E–73E

    Article  CAS  PubMed  Google Scholar 

  2. Ackermann MJ, Yoo T, Jenkins D (2001) From data to knowledge—The Visible Human Project continues. Medinfo 10:887–890

    PubMed  Google Scholar 

  3. Bisset R (1998) Magnetic resonance imaging may be alternative to necropsy. BMJ 317:1450

    CAS  Google Scholar 

  4. Bisset R, Thomas N, Turnbull I, Lee S (2002) Postmortem examinations using magnetic resonance imaging: four year review of a working service. BMJ 324:1423–1424

    Article  CAS  PubMed  Google Scholar 

  5. Choudhury L, Mahrholdt H, Wagner A et al. (2002) Myocardial scarring in asymptomatic or mildly symptomatic patients with hypertrophic cardiomyopathy. J Am Coll Cardiol 40:2156–2164

    Article  PubMed  Google Scholar 

  6. Heinrichs T, Beuing O, Jachau K et al. (2003). Supplementband zum 84. Deutschen Röntgenkongress Wiesbaden: PO 148

  7. Hsu J, Johnson G, Smith W, Reimer K, Ideker R (1994) Magnetic resonance imaging of chronic myocardial infarcts in formalin-fixed human autopsy hearts. Circulation 89:2133–2140

    CAS  PubMed  Google Scholar 

  8. Keelan P, Bielak L, Ashai K et al. (2001) Long-term prognostic value of coronary calcification detected by electron-beam computed tomography in patients undergoing coronary angiography. Circulation 104:412–417

    CAS  PubMed  Google Scholar 

  9. Kuchheuser W, Heinrichs T, Reck J, Beck N, Jachau K, Schöning R, Krause D (2003) Postmortale CT- und MRT-Untersuchungen isolierter menschlicher Organe am Beispiel von Leber und Nieren. Rechtsmedizin 13:256

    Google Scholar 

  10. Myers JC, Okoye MI, Kiple D, Kimmerle EH, Reinhard KJ (1999) Three-dimensional (3-D) imaging in post-mortem examinations: elucidation and identification of cranial and facial fractures in victims of homicide utilizing 3-D computerized imaging reconstruction techniques. Int J Legal Med 113:33–37

    CAS  PubMed  Google Scholar 

  11. Nieman K, Oudkerk M, Rensing BJ, Ooijen P van, Munne A, Geuns RJ van, Feyter PJ de (2001) Coronary angiography with multi-slice computed tomography. Lancet 357:599–603

    CAS  PubMed  Google Scholar 

  12. Oehmichen M, Gehl HB, Meissner C, Petersen D, Hoche W, Gerling I, König HG (2003) Forensic pathological aspects of postmortem imaging of gunshot injury to the head: documentation and biometric data. Acta Neuropathol 105:570–580

    CAS  PubMed  Google Scholar 

  13. Patriquin L, Kassarjian A, O’Brien M, Andry C, Eustace S (2001) Postmortem whole-body magnetic resonance imaging as an adjunct to autopsy: preliminay clinical experience. J Magn Reson Imaging 13:277–287

    Article  CAS  PubMed  Google Scholar 

  14. Rah BR, Katz RJ, Wassermann AG, Reiner JS (2001) Post-mortem three-dimensional reconstruction of the entire coronary arterial circulation using electron-beam computed tomography. Circulation 104:3168

    CAS  PubMed  Google Scholar 

  15. Rodrigez E, Soler R, Juffe A, Salgado L (2001) CT and MR findings in a calcified myocardial tuberculoma of the left ventricle. J Comput Assist Tomogr 25:577–579

    Article  PubMed  Google Scholar 

  16. Schulthess GK, Schwitter J (2001) Cardiac MR imaging: facts and fiction. Radiology 218:326–328

    PubMed  Google Scholar 

  17. Schweitzer W, Robertson S, Stella D, Czucman F, Schaepman M, Dangel S, Dirnhofer R (1999) Comparison of magnetic resonance imaging and cardiac pathology in 50 native human autopsy hearts. Proceedings of the International Association of Forensic Sciences, 15th Triennial Meeting, Los Angeles

  18. Smith DR, Limbird KG, Hoffman JM (2002) Identification of human skeletal remains by comparison of bony details of the cranium using computerized tomographic (CT) scans. J Forensic Sci 47:937–939

    PubMed  Google Scholar 

  19. Stanford W (1999) Coronary artery calcification as an indicator of preclinical coronary artery diease. Radiographics 19:1409–1419

    CAS  PubMed  Google Scholar 

  20. Stein KM, Ruf R, Matejic D, Mattern R (2003) Methodenentwicklung zur Darstellung subduraler Blutungsquellen mit der postmortalen Computertomographie. Rechtsmedizin 13:228

    Google Scholar 

  21. Thali MJ, Schwab CM, Tairi K, Dirnhofer R, Vock P (2002) Forensic radiology with cross-section modalities: spiral CT evaluation of a knife wound to the aorta. J Forensic Sci 47:1041–1045

    PubMed  Google Scholar 

  22. Thali MJ, Yen K, Plattner T, Schweizer W, Vock P, Ozdoba C, Dirnhofer R (2002) Charred body: virtual autopsy with multi-slice tomography and magnetic resonance imaging. J Forensic Sci 47:1326–1331

    PubMed  Google Scholar 

  23. Thali MJ, Yen K, Schweizer W et al. (2003) Virtopsy, a new imaging horizon in forensic pathology: virtual autopsy by postmortem multislice computed tomography (MSCT) and magnetic resonance imaging (MRI)—A feasibility study. J Forensic Sci 48:386–403

    PubMed  Google Scholar 

  24. Uchigasaki S, Osterhelweg L, Sperhake JP, Püschel K, Oshida S (2003) Herzbeuteltamponade—Diagnose durch Ultraschall vor der Obduktion. 12. Frühjahrstagung, Kiel, V3

Download references

Interessenkonflikt:

Der korrespondierende Autor versichert, dass keine Verbindungen mit einer Firma, deren Produkt in dem Artikel genannt ist, oder einer Firma, die ein Konkurrenzprodukt vertreibt, bestehen.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to K. Jachau.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Jachau, K., Heinrichs, T., Kuchheuser, W. et al. CT- und MRT-Befunde an isolierten Leichenherzen. Rechtsmedizin 14, 109–116 (2004). https://doi.org/10.1007/s00194-004-0252-8

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00194-004-0252-8

Schlüsselwörter

Keywords

Navigation