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Lithiumintoxikation imitiert Alzheimer-Demenz in PET und klinischem Befund

Lithium intoxication mimics Alzheimer’s disease in PET and clinical findings

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Zusammenfassung

Bei der Diagnostik der Alzheimer-Demenz (AD) werden neben klinischen Gesichtspunkten zunehmend auch funktionsmorphologische Untersuchungen herangezogen. Mit der hier vorgelegten Kasuistik einer Patientin, die bei einer Lithiumintoxikation klinisch und im 18-FDG-PET das Bild einer AD zeigte, wollen wir aufzeigen, dass auch bei klinisch und funktionsmorphologischem Bild einer AD differenzialdiagnostische Erwägungen sorgfältig geprüft werden müssen, und auf einen der möglichen Fallstricke aufmerksam machen.

Summary

To improve specificity and sensitivity in the diagnosis of Alzheimer’s disease, neuropsychological tests and fluorine-18-FDG-PET are increasingly used. Here we present a patient whose lithium intoxication mimicked Alzheimer’s disease both clinically and in 18-FDG-PET. This case serves as a reminder of the importance of the differential diagnosis of dementias and is intended to highlight one potential pitfall.

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Authors and Affiliations

  1. Klinik für Psychiatrie der Johannes-Gutenberg-Universität, Mainz

    Peter Tonn & Norbert Dahmen

  2. Klinik für Nuklearmedizin der Johannes-Gutenberg-Universität, Mainz

    Peter Bartenstein

  3. Klinik für Psychiatrie der Johannes-Gutenberg-Universität, Untere Zahlbacher Straße 8, 55131, Mainz

    Peter Tonn

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  1. Peter Tonn
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  2. Peter Bartenstein
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  3. Norbert Dahmen
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Correspondence to Peter Tonn.

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Tonn, P., Bartenstein, P. & Dahmen, N. Lithiumintoxikation imitiert Alzheimer-Demenz in PET und klinischem Befund . Nervenarzt 76, 613–616 (2005). https://doi.org/10.1007/s00115-004-1758-8

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  • DOI: https://doi.org/10.1007/s00115-004-1758-8

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