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Neuromonitoring in der Intensivmedizin mit S-100 Protein

Neuromonitoring with S-100 protein in the intensive care unit

  • Intensivmedizin
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Zusammenfassung

Der Einsatz von neurobiochemischen Markern, wie S-100 Protein, zur Diagnose und Prognose von akuten neurologischen Krankheitsbildern ist in den letzten Jahren Gegenstand intensiver experimenteller und klinischer Untersuchungen gewesen. Der vorliegende Artikel gibt einen Überblick über den aktuellen Stand der Forschung, die biochemischen Eigenschaften, die klinischen Einsatzmöglichkeiten und die Limitationen von S-100 Protein in Bezug auf die akuten neurologischen Erkrankungen, die dem Intensivmediziner am häufigsten begegnen.

Abstract

During the last years biochemical neuromonitoring with various molecules such as S-100 protein has become popular. A huge number of investigations both experimental and clinical have been undertaken to determine diagnosis and prognosis of patients with acute neurologic diseases. This article gives a review on the current knowledge, indications and limitations on the use of S-100 protein with regard to most of the acute neurological diseases an intensivist is confronted with in everyday practice.

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Authors and Affiliations

  1. Klinik für Anästhesiologie, Universitätsklinikum Aachen

    M. Fries, J. Bickenbach, S. Beckers, D. Henzler, R. Rossaint & R. Kuhlen

  2. Klinik für Anästhesiologie, Universitätsklinikum Aachen, Pauwelsstr. 30, 52074, Aachen

    M. Fries

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  1. M. Fries
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  2. J. Bickenbach
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  3. S. Beckers
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Correspondence to M. Fries.

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Fries, M., Bickenbach, J., Beckers, S. et al. Neuromonitoring in der Intensivmedizin mit S-100 Protein. Anaesthesist 53, 959–964 (2004). https://doi.org/10.1007/s00101-004-0743-8

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