Skip to main content
Log in

Phytochemical constituents from the herba ofArtemisia apiacea

  • Research Articles
  • Articles
  • Published:
Archives of Pharmacal Research Aims and scope Submit manuscript

Abstract

Four compounds of a coumarin, a steroid and two flavonoids were isolated from the herba ofArtemisia apiacea by open column chromatography. Their structures were elucidated as artemicapin C, apigenin, daucosterol and cacticin by chemical and spectroscopic analysis. This is the first report of the isolation of these compounds from this plant.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Aquino, R., Morelli, S., Tomaino, A., Pellegrino, M., Saija, A., Grumetto, L., Puglia, C., Ventura, D., and Bonina, F., Antioxidant and photoprotective activity of a crude extract ofCulcitum reflexum H. B. K. leaves and their major flavonoids.J. Ethnopharmacol., 79, 183–191 (2002).

    Article  PubMed  CAS  Google Scholar 

  • Avallone, R., Zanoli, P., Puia, G., Kleinschnitz, M.,Schreier, P., and Baraldi, M., Pharmacological profile of apigenin, a flavonoid isolated fromMatricaria chamomilla. Biochem. Pharmacol., 59, 1387–1394 (2000).

    Article  CAS  Google Scholar 

  • Chang I. M., Yun-Choi, H. S., and Yamasaki, K., Revision ofp13C NMR assignment of p-sitosterol and β-sitosteryl-3-0-β-D- glucopyranoside isolated fromPlantago asiatica seed. Kor. J. Pharmacogn., 12, 12–24 (1981).

    CAS  Google Scholar 

  • Jang, M-H., Wu, T-S., and Su, J-D., Studies on antioxidative components fromArtemisia capillaris Thunb.Shipin Kexue, 23, 594–607 (1996).

    CAS  Google Scholar 

  • Kang, S. S., Um, B. H., Kim, J. S., and Ahn, B. T., Isolation of flavonoids from Evodiae fructus.Kor. J. Pharmacogn., 28, 9–14 (1997).

    CAS  Google Scholar 

  • Kim, K. S., Shim, S. H., Jang, J. M., Cheong, J. H., and Kim, B- K., A study on hair-growth activity ofArtemisia apiacea Hance.Yakhak Hoeji, 43, 798–801 (1999).

    CAS  Google Scholar 

  • Kim, O. C., and Jang, H. J., Volatile components ofArtemisia apiacea Herba.Hanguk Nonghwa Hakhoechi, 37, 37–42 (1994).

    CAS  Google Scholar 

  • Lee, H. B., Kwak, J. H., Zee, O. P., and Yoo, S. J., Flavonoids fromCircum rhinoceros. Arch. Pharm. Res., 17, 273–277 (1994).

    CAS  Google Scholar 

  • Lee, Y. H., Lee, I. R., Woo, W. S., and Park, C. H., Flavonoids ofElscholtzia cristata. Arch. Pharm. Res., 11, 247–249 (1988).

    Article  CAS  Google Scholar 

  • Markham, K. R., Techniques of flavonoid identification, Academic press, London, pp. 87–90, (1982).

    Google Scholar 

  • Shang-jiang, D., Gariboldi, P., and Jommi, G., Constituents of Shashen (Adenophora axilliflora).Planta Med., 49, 317–320 (1986).

    Google Scholar 

  • Shimomura, H., Sashida, Y., and Ohshima, Y., Coumarins fromArtemisia apiacea. Phytochemistry, 18, 1761–1762 (1979).

    Article  CAS  Google Scholar 

  • Shimomura, H., Sashida, Y., and Ohshima, Y., The chemical components ofArtemisia apiacea Hance, More coumarins from the flower heads.Chem. Pharm. Bull., 28, 347–348 (1980a).

    CAS  Google Scholar 

  • Shimomura, H., Sashida, Y., Oshima, Y., Azuma, T., and Saitoh, M., The chemical components ofArtemisia apiacea Hance, Components of stems and leaves.Yakugaku Zasshi, 100, 1164–1166 (1980b).

    CAS  Google Scholar 

  • Sugiyama, M. and Seki, J., In vivo application of lipoproteins as drug carriers: pharmacological evaluation of sterylglucoside- lipoprotein complexes.Targ. Diagn. Ther. 5, 315–350 (1991).

    CAS  Google Scholar 

  • Tan, R. X., Zheng, W. F., and Tang, H. Q., Biologically active substances from the genusArtemisia. Planta Med., 64, 295–302 (1998).

    Article  CAS  Google Scholar 

  • Wu, T. S., Tsang, Z. J., Wu, P. L., Lin, F. W., Li, C. Y., Teng, C. M., and Lee, K. H., New constituents and antiplatelet aggregation and anti-HIV principles ofArtemisia capillaris. Bioorg. Med. Chem., 9, 77–83 (2001).

    Article  CAS  Google Scholar 

  • Yano, K., Mono- and sesqui-terpenes of the essential oils fromArtemisia japonica andArtemisia apiacea. Flavour Ind., 1, 328–330 (1970).

    CAS  Google Scholar 

  • Yook, C., S., Coloured medicinal plants of Korea, p. 522, (1989).

  • Zanoli, P., Avallone, R., and Baraldi, M., Behavioral characterization of the flavonoids apigenin and chrysin.Fitoterapia, 71, S117-S123 (2000).

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Bak-Kwang Kim.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Lee, S., Kim, K.S., Jang, J.M. et al. Phytochemical constituents from the herba ofArtemisia apiacea . Arch Pharm Res 25, 285–288 (2002). https://doi.org/10.1007/BF02976627

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02976627

Key words

Navigation