Abstract
Four compounds of a coumarin, a steroid and two flavonoids were isolated from the herba ofArtemisia apiacea by open column chromatography. Their structures were elucidated as artemicapin C, apigenin, daucosterol and cacticin by chemical and spectroscopic analysis. This is the first report of the isolation of these compounds from this plant.
Similar content being viewed by others
References
Aquino, R., Morelli, S., Tomaino, A., Pellegrino, M., Saija, A., Grumetto, L., Puglia, C., Ventura, D., and Bonina, F., Antioxidant and photoprotective activity of a crude extract ofCulcitum reflexum H. B. K. leaves and their major flavonoids.J. Ethnopharmacol., 79, 183–191 (2002).
Avallone, R., Zanoli, P., Puia, G., Kleinschnitz, M.,Schreier, P., and Baraldi, M., Pharmacological profile of apigenin, a flavonoid isolated fromMatricaria chamomilla. Biochem. Pharmacol., 59, 1387–1394 (2000).
Chang I. M., Yun-Choi, H. S., and Yamasaki, K., Revision ofp13C NMR assignment of p-sitosterol and β-sitosteryl-3-0-β-D- glucopyranoside isolated fromPlantago asiatica seed. Kor. J. Pharmacogn., 12, 12–24 (1981).
Jang, M-H., Wu, T-S., and Su, J-D., Studies on antioxidative components fromArtemisia capillaris Thunb.Shipin Kexue, 23, 594–607 (1996).
Kang, S. S., Um, B. H., Kim, J. S., and Ahn, B. T., Isolation of flavonoids from Evodiae fructus.Kor. J. Pharmacogn., 28, 9–14 (1997).
Kim, K. S., Shim, S. H., Jang, J. M., Cheong, J. H., and Kim, B- K., A study on hair-growth activity ofArtemisia apiacea Hance.Yakhak Hoeji, 43, 798–801 (1999).
Kim, O. C., and Jang, H. J., Volatile components ofArtemisia apiacea Herba.Hanguk Nonghwa Hakhoechi, 37, 37–42 (1994).
Lee, H. B., Kwak, J. H., Zee, O. P., and Yoo, S. J., Flavonoids fromCircum rhinoceros. Arch. Pharm. Res., 17, 273–277 (1994).
Lee, Y. H., Lee, I. R., Woo, W. S., and Park, C. H., Flavonoids ofElscholtzia cristata. Arch. Pharm. Res., 11, 247–249 (1988).
Markham, K. R., Techniques of flavonoid identification, Academic press, London, pp. 87–90, (1982).
Shang-jiang, D., Gariboldi, P., and Jommi, G., Constituents of Shashen (Adenophora axilliflora).Planta Med., 49, 317–320 (1986).
Shimomura, H., Sashida, Y., and Ohshima, Y., Coumarins fromArtemisia apiacea. Phytochemistry, 18, 1761–1762 (1979).
Shimomura, H., Sashida, Y., and Ohshima, Y., The chemical components ofArtemisia apiacea Hance, More coumarins from the flower heads.Chem. Pharm. Bull., 28, 347–348 (1980a).
Shimomura, H., Sashida, Y., Oshima, Y., Azuma, T., and Saitoh, M., The chemical components ofArtemisia apiacea Hance, Components of stems and leaves.Yakugaku Zasshi, 100, 1164–1166 (1980b).
Sugiyama, M. and Seki, J., In vivo application of lipoproteins as drug carriers: pharmacological evaluation of sterylglucoside- lipoprotein complexes.Targ. Diagn. Ther. 5, 315–350 (1991).
Tan, R. X., Zheng, W. F., and Tang, H. Q., Biologically active substances from the genusArtemisia. Planta Med., 64, 295–302 (1998).
Wu, T. S., Tsang, Z. J., Wu, P. L., Lin, F. W., Li, C. Y., Teng, C. M., and Lee, K. H., New constituents and antiplatelet aggregation and anti-HIV principles ofArtemisia capillaris. Bioorg. Med. Chem., 9, 77–83 (2001).
Yano, K., Mono- and sesqui-terpenes of the essential oils fromArtemisia japonica andArtemisia apiacea. Flavour Ind., 1, 328–330 (1970).
Yook, C., S., Coloured medicinal plants of Korea, p. 522, (1989).
Zanoli, P., Avallone, R., and Baraldi, M., Behavioral characterization of the flavonoids apigenin and chrysin.Fitoterapia, 71, S117-S123 (2000).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Lee, S., Kim, K.S., Jang, J.M. et al. Phytochemical constituents from the herba ofArtemisia apiacea . Arch Pharm Res 25, 285–288 (2002). https://doi.org/10.1007/BF02976627
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF02976627