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MR imaging of deferoxamine-induced bone dysplasia in an 8-year-old female with thalassemia major

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Abstract

Bone changes in thalassemic patients receiving deferoxamine therapy for iron chelation include metaphyseal and growth plate irregularities. We present a case of an 8-year-old female with thalassemia major, who had magnetic resonance imaging after plain radiographs had shown metaphyseal changes in the distal femur. The signal characteristics of these abnormalities were consistent with hyaline cartilage; the surrounding marrow showed no evidence of iorn overload.

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Authors and Affiliations

  1. Department of Radiology and Nuclear Medicine, The Hospital for Special Surgery, New York, NY, USA

    T. T. Miller & J. J. Kaye

  2. Department of Orthopedic Surgery, The Hospital for Special Surgery, New York, NY, USA

    G. Caldwell & S. Burke

  3. Department of Pediatrics, The Mount Sinai Medical Center, New York, NY, USA

    S. Arkin

  4. Department of Radiology, The New York Hospital, Cornell University Medical Center, New York, NY, USA

    P. W. Brill

Authors
  1. T. T. Miller
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  2. G. Caldwell
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  3. J. J. Kaye
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  4. S. Arkin
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  5. S. Burke
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  6. P. W. Brill
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Miller, T.T., Caldwell, G., Kaye, J.J. et al. MR imaging of deferoxamine-induced bone dysplasia in an 8-year-old female with thalassemia major. Pediatr Radiol 23, 523–524 (1993). https://doi.org/10.1007/BF02012138

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  • DOI: https://doi.org/10.1007/BF02012138

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