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Bromocriptine reduces the size of cells in prolactin-secreting pituitary adenomas

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Summary

The morphometric analysis of the size of adenomatous prolactin cells shows that bromocriptine-induced cell skrinkage halts if treatment with the drug is discontinued for more than 2 days. Different cell components (nucleus, cytoplasm, nucleolus) do not react to treatment to the same extent.

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References

  1. Flückiger, E., del Pozo, E., and Werder, K. von, Prolactin: Physiology, pharmacology, and clinical findings, p. 189. Springer, Berlin/Heidelberg/New York 1982.

    Google Scholar 

  2. Pawlikowski, M., Kunert-Radek, J., and Stepien, H., J. Endocr.79 (1978) 245.

    PubMed  Google Scholar 

  3. Quadri, S. K., Lu, K. H., and Meites, J., Science176 (1972) 417.

    PubMed  Google Scholar 

  4. Rengachari, S. S., Tomita, T., Jefferies, B. F., and Watanabe, I., Neurosurgery10 (1982) 242.

    PubMed  Google Scholar 

  5. Landolt, A. M., Neurosurgery11 (1982) 395.

    PubMed  Google Scholar 

  6. Landolt, A. M., Acta neurochir., suppl.25 (1975) 4.

    Google Scholar 

  7. Weibel, E. R., Kistler, G. S., and Scherle, F. W., J. Cell Biol.30 (1966) 23.

    PubMed  Google Scholar 

  8. Maurer, R. A., J. biol. Chem.255 (1980) 8092.

    PubMed  Google Scholar 

  9. Maurer, R. A., Nature294 (1981) 94.

    Article  PubMed  Google Scholar 

  10. Miller, Jr., O. L., Beatty, B. R., Hamkalo, B. A., and Thomas, Jr., C. A. Cold Spring Harb. Symp. quant. Biol.35 (1970) 505.

    Google Scholar 

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Authors and Affiliations

  1. Department of Neurosurgery, University Hospital, CH-8091, Zurich, Switzerland

    A. M. Landolt, H. Minder, V. Osterwalder & Th. A. Landolt

Authors
  1. A. M. Landolt
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  2. H. Minder
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  3. V. Osterwalder
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  4. Th. A. Landolt
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Additional information

Acknowledgments. We thank the EMDO Foundation, Zurich and the Sandoz-Foundation, Basel for financial support and Susan Eastwood-Berry, San Francisco for editorial assistance.

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Landolt, A.M., Minder, H., Osterwalder, V. et al. Bromocriptine reduces the size of cells in prolactin-secreting pituitary adenomas. Experientia 39, 625–626 (1983). https://doi.org/10.1007/BF01971131

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  • DOI: https://doi.org/10.1007/BF01971131

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