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Side effects of positive pressure ventilation on hepatic function and splanchnic circulation

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International journal of clinical monitoring and computing

Summary

Positive pressure ventilation is associated with a reduction and redistribution of cardiac output. Splanchnic blood flow is decreased. Blood supply of the liver is reduced exceeding the fall in cardiac output. As a result oxygen transport to the mesenteric bed and liver is curtailed. There is a concomitant impairment of hepatic venous outflow. These hemodynamic changes may cause functional, structural and metabolic disturbances in organs whose blood supply arises from splanchnic circulation.

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Authors and Affiliations

  1. Institute of Anaesthesiology, Faculty of Clinical Medicine Mannheim, University of Heidelberg, FRG

    K. Geiger, M. Georgieff & H. Lutz

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  1. K. Geiger
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  2. M. Georgieff
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  3. H. Lutz
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Geiger, K., Georgieff, M. & Lutz, H. Side effects of positive pressure ventilation on hepatic function and splanchnic circulation. International Journal of Clinical Monitoring and Computing 3, 103–106 (1986). https://doi.org/10.1007/BF01880762

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