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Extensive lymphadenectomy for thoracic esophageal carcinoma: A two-stage operation for high-risk patients

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Abstract

Extensive lymphadenectomy (ELA) for esophageal carcinoma has always been limited to low-risk patients; however, we have developed a two-stage operation which extends the indications for ELA to include certain high-risk patients. Of 70 patients who underwent transthoracic subtotal esophagectomy for thoracic esophageal carcinoma between 1986 and 1991, 48 qualified for ELA which was performed on 45, including 27 low-risk patients (group A) whom underwent the traditional one-stage operation, while 18 high-risk patients underwent the two-stage operation (group B). The number of hospital deaths and postoperative complications was similar between the two groups. The median survival was 26 months in group B and 17 months in group A. The 40-day delay in resection of the neck and abdominal nodes in the two-stage operation did not significantly affect lymph node metastases, postoperative recurrence, or long-term survival. Thus, the two-stage operation is an oncologically meaningful approach to the treatment of high-risk patients who present with thoracic esophageal carcinoma.

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Saito, T., Shimoda, K., Shigemitsu, Y. et al. Extensive lymphadenectomy for thoracic esophageal carcinoma: A two-stage operation for high-risk patients. Surg Today 24, 610–615 (1994). https://doi.org/10.1007/BF01833725

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