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Clinical evaluation of a multiparameter intra-arterial blood-gas sensor

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Abstract

Objective

To evaluate the in vivo performance of a continuous, intra-arterial, multiparameter blood-gas sensor containing a thermocouple, miniaturized polarographic oxygen electrode, as well as fiberoptic pH andpCO2 sensors.

Design

Prospective, multicenter study comparing pH, PaCO2, and PaO2 measurements from the intraarterial sensor with those obtained from a conventional, laboratory blood-gas monitor.

Setting

Intensive care units in three academic medical centers.Patients: Adult ICU patients (n=26) with a clinical need for a radial artery catheter and frequent monitoring of arterial blood gases for ≥3 days.

Interventions

All patientys had the multiparameter intra-arterial sensor placed through a 20-gauge catheter into the radial artery. Every 4 h, or more frequently if clinically indicated, a blood-gas sample was withdrawn from the radial artery catheter and sent to the laboratory for analysis using a conventional laboratory bloodgas analyzer. Immediately pior to withdrawal of the arterial blood, values for pH, PaCO2, and PaO2 from the multiparameter intra-arterial sensor were recorded.

Measrements and main results

The multiparameter sensor was placed into 26 patients. In 7 of the patients, premature discontinuation of monitoring was necessary because of dampening of the pressure tracing, difficulty in withdrawing blood from the arterial catheter, or bending of the extra-arterial fiberoptic channel owing to the cable being inadequately secured (mean monitoring time in these 7 patients: 40.6±25.7 h). In the other 19 patients, monitoring was continued until no longer clinically indicated. In these patients, a total or 341 data sets was collected, with the average length of monitoring being 69.9±37.9 h (range 22.0 to 57.9 h). Comparison of the sensor values with those from the bloodgas analyzer showed bias and precision values of 0.006 and 0.026 for arterial pH−1.19% and 12.54% for PaO2, and 1.28 mmHg and 2.48 mmHg for PaCO2, respectively. No complications were associated with the intra-arterial sensor.

Conclusions

Clinical performance of this intra-arterial, multiparameter blood-gas sensor demonstrated stability, consistency, and accuracy comparable to laboratory blood-gas analyzers. The present multiparameter, intravascular

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Authors and Affiliations

  1. Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Health Sciences Center, 4200 E. Ninth Avenue, Box C272, 80262, Denver, CO, USA

    E. Abraham

  2. Department of Anesthesiology, University of Florida School of Medicine, Gainesville, Florida, USA

    T. J. Gallagher

  3. Bionedical Sensors/Pfizer, Malvern, Pennsylvania, USA

    S. Fink

Authors
  1. E. Abraham
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  2. T. J. Gallagher
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  3. S. Fink
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Abraham, E., Gallagher, T.J. & Fink, S. Clinical evaluation of a multiparameter intra-arterial blood-gas sensor. Intensive Care Med 22, 507–513 (1996). https://doi.org/10.1007/BF01712177

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  • DOI: https://doi.org/10.1007/BF01712177

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