Skip to main content
Log in

A flexible system for closed-loop ventilator development

  • Articles
  • Published:
Journal of Medical Systems Aims and scope Submit manuscript

Abstract

The feasibility of using a microcomputer to regulate the delivery of artificial ventilation was investigated experimentally. To carry out this study, a sampled-data proportional, integral, derivative feedback controller was implemented on a commercial microcomputer and interfaced with a digital/analogue model of a prototype ventilator and two-compartment patient. The microcomputer sampled end-tidal CO2 and calculated a new frequency of ventilation from the difference of end-tidal CO2 and a desired set point value. Use of a microcomputer programmable in BASIC allowed easy manipulation of feedback structure. With the proper choice of feedback constants, the microcomputer was able to maintain end-tidal CO2 at a desired set point.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. A Review and Analysis of Pulmonary Device Needs and Priorities, distributed by Division of Lung Diseases and Division of Technological Applications, National Heart and Lung Institute, Nov. 1, 1972.

  2. Mitamura, Y., Mikami, T., Sugawara, H., and Yoshimoto, C., An optimally controlled respirator.IEEE Trans. Biomed. Eng. BME-18: 330–338, 1971.

    Google Scholar 

  3. Hilberman, M., Schill, J.P., and Peters, R.M., On-line digital analysis of respiratory mechanics and the automation of respirator control.J. Thorac. Cardiovasc. Surg. 58: 821–828, 1960.

    Google Scholar 

  4. Mitamura, Y., Mikami, T., and Yamamoto, K., A dual control system for assisting respiration.Med. Biol. Eng. 13: 846–853, 1975.

    Google Scholar 

  5. Simes, J., Asche, D., Cook, A., Hathaway, J., and Zumstein, R., Microprocessors used in the monitoring and control of artificial ventilation of the human lung.Proceedings of the 1976 Joint Automatic Control Conference, Purdue University, 1976.

  6. Engelman, F.A., and Cook, A.M., Digital control of automatic ventilators.IEEE Trans. Biomed. Eng. BME-24: 188–190, 1977.

    Google Scholar 

  7. Milhorn, H.T.,The Application of Control Theory to Physiological Systems W.B. Saunders, Philadelphia, 1966.

    Google Scholar 

  8. Training Test Lung USER's MANUAL. Michigan Instruments, Grand Rapids, Michigan, 1977.

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Marsh, W.I., Smith, W.D. A flexible system for closed-loop ventilator development. J Med Syst 6, 53–59 (1982). https://doi.org/10.1007/BF00994120

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00994120

Keywords

Navigation