Abstract
The feasibility of using a microcomputer to regulate the delivery of artificial ventilation was investigated experimentally. To carry out this study, a sampled-data proportional, integral, derivative feedback controller was implemented on a commercial microcomputer and interfaced with a digital/analogue model of a prototype ventilator and two-compartment patient. The microcomputer sampled end-tidal CO2 and calculated a new frequency of ventilation from the difference of end-tidal CO2 and a desired set point value. Use of a microcomputer programmable in BASIC allowed easy manipulation of feedback structure. With the proper choice of feedback constants, the microcomputer was able to maintain end-tidal CO2 at a desired set point.
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References
A Review and Analysis of Pulmonary Device Needs and Priorities, distributed by Division of Lung Diseases and Division of Technological Applications, National Heart and Lung Institute, Nov. 1, 1972.
Mitamura, Y., Mikami, T., Sugawara, H., and Yoshimoto, C., An optimally controlled respirator.IEEE Trans. Biomed. Eng. BME-18: 330–338, 1971.
Hilberman, M., Schill, J.P., and Peters, R.M., On-line digital analysis of respiratory mechanics and the automation of respirator control.J. Thorac. Cardiovasc. Surg. 58: 821–828, 1960.
Mitamura, Y., Mikami, T., and Yamamoto, K., A dual control system for assisting respiration.Med. Biol. Eng. 13: 846–853, 1975.
Simes, J., Asche, D., Cook, A., Hathaway, J., and Zumstein, R., Microprocessors used in the monitoring and control of artificial ventilation of the human lung.Proceedings of the 1976 Joint Automatic Control Conference, Purdue University, 1976.
Engelman, F.A., and Cook, A.M., Digital control of automatic ventilators.IEEE Trans. Biomed. Eng. BME-24: 188–190, 1977.
Milhorn, H.T.,The Application of Control Theory to Physiological Systems W.B. Saunders, Philadelphia, 1966.
Training Test Lung USER's MANUAL. Michigan Instruments, Grand Rapids, Michigan, 1977.
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Marsh, W.I., Smith, W.D. A flexible system for closed-loop ventilator development. J Med Syst 6, 53–59 (1982). https://doi.org/10.1007/BF00994120
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DOI: https://doi.org/10.1007/BF00994120