Abstract
We present a 1-month-old girl with a congenital nephrotic syndrome and unusual histological findings. Immunofluorescence microscopy demonstrated granular mesangial deposition of C1q and electron microscopy revealed electron-dense mesangial deposits. Her heavy proteinuria gradually decreased and the steroid therapy did not have a significant effect. Her renal function was normal throughout the entire period of observation. The clinical evidence and histopathological features of this patient were compatible with C1q nephropathy.
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Kuwano, M., Ito, Y., Amamoto, Y. et al. A case of congenital nephrotic syndrome associated with positive C1q immunofluorescence. Pediatr Nephrol 7, 452–454 (1993). https://doi.org/10.1007/BF00857571
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DOI: https://doi.org/10.1007/BF00857571