Summary
Lysozyme, a1-Antichymotrypsin and a1-Antitrypsin were demonstrated by an immunoperoxidase technique (PAP) in malignant cells of adenocarcinomas of the stomach but not of the large intestine. Lymph-node metastases showed identical immunoreactivity to that of the primary tumour. Neoplasms arising from the cardia, the body and the pyloric antrum of the stomach showed different immunostaining reactions: It seems that these differences partly reflect the distribution of lysozyme, a1-Antichymotrypsin and a1-Antitrypsin in the normal gastric mucosa. The usefulness of our findings in the identification of the primary tumour in cases of lymph node metastases of unknown origin, is also discussed.
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Kittas, C., Aroni, K., Kotsis, L. et al. Distribution of lysozyme, a1-Antichymotrypsin and a1-Antitrypsin in adenocarcinomas of the stomach and large intestine. Vichows Archiv A Pathol Anat 398, 139–147 (1982). https://doi.org/10.1007/BF00618865
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DOI: https://doi.org/10.1007/BF00618865