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Acute oral toxicity of 4-dimethylaminophenol to the gastrointestinal tract, liver and kidney of the rat

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Abstract

Single oral doses up to 25 mg/kg body weight of the methaemoglobin-inducing cyanide antidote, 4-dimethylaminophenol (DMAP) did not result in any gross or histological abnormality in the gastrointestinal tract, liver and kidneys of rats killed up to 24 h after the dose. In animals kept for 7 days after the dose to abnormality was observed in the organs examined or in blood samples taken during the course of the experiment.

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Marrs, T.C., Bright, J.E. & Swanston, D.W. Acute oral toxicity of 4-dimethylaminophenol to the gastrointestinal tract, liver and kidney of the rat. Arch Toxicol 50, 89–92 (1982). https://doi.org/10.1007/BF00569241

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  • DOI: https://doi.org/10.1007/BF00569241

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