Abstract
An unusually high prevalence (10%) of scoliosis is described in a series of 151 patients aged four years and older with cystic fibrosis. The scolioses were of the late onset (juvenile and adolescent) type, being typically thoracic with the curve convex to the right, although there was no significant preference for either sex. No direct relationship was found between the spinal curvature and the severity or distribution of the lung disease, although the worse scolioses tended to occur in patients with relatively severe pulmonary involvement. There was no evidence of metabolic bone disease as a predisposing cause. Some indication of a familial tendency towards scoliosis was apparent, and a genetic or constitutional basis is postulated with an unknown precipitating factor.
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References
Cobb JR (1948) Outline for study of scoliosis. Am Acad Orthop Surg 5:261
DiSant'Agnese PA, Davis PB (1976) Research in cystic fibrosis (first of three parts). N Engl J Med 295:481
DiSant'Agnese PA, Davis PB (1976) Research in cystic fibrosis (third of three parts). N Engl J Med 295:597
Erkkila JC, Warwick WJ, Bradford DS (1978) Spine deformities and cystic fibrosis. Clin Orthop 131:146
Harrington PR (1977) The etiology of idiopathic scoliosis. Clin Orthop 126:17
James JIP (1976) Scoliosis. Churchill Livingstone, Edinburgh London New York p 38
Kane WJ (1977) Scoliosis prevalence. A call for a statement of terms. Clin Orthop 126:43
Lonstein JE (1977) Screening for spinal deformities in Minnesota schools. Clin Orthop 126:33
Riseborough EJ, Wynne-Davies R (1973) A genetic survey of idiopathic scoliosis in Boston, Massachusetts. J Bone Joint Surg [Am] 55:974
Scott J, Elias E, Moult PJA, Barnes S, Wills MR (1977) Rickets in cystic fibrosis with myopathy, pancreatic insufficiency and proximal renal tubular dysfunction. Am J Med 63:488
Shands AR Jr, Eisberg HB (1955) The incidence of scoliosis in the state of Delaware. A study of 50,000 minifilms of the chest made during a survey for tuberculosis. J Bone Joint Surg [Am] 37:1243
Wynne-Davies R (1968) Familial (idiopathic) scoliosis. J Bone Joint Surg [Br] 50:24
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Paling, M.R., Spasovsky-Chernick, M. Scoliosis in cystic fibrosis — An appraisal. Skeletal Radiol 8, 63–66 (1982). https://doi.org/10.1007/BF00361373
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DOI: https://doi.org/10.1007/BF00361373