Summary
Two contrasting cases of cervical intramedullary cavernous angioma in young female patients are reported. One patient had a 3-year course of step-wise progressive tetraparesis; at each of the five events intramedullary bleeding from a cryptic vascular malformation at C6–7 level was diagnosed by MRI. The other patient presented with one episode which led to MRI diagnosis of a vascular malformation at the C2 level. Both patients eventually underwent complete surgical excision of the angioma with subsequent steady improvement of the neurological deficit.
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Ansari F (1965) Hämatomyelie bei arteriovenösem Angiom des Rückenmarks. Ein Beitrag zur Pathogenese der Foix-Alajouanine'schen Krankheit. Beitr Pathol Anat 131:137–161
Barnwell SL, Dowd CF, Davis RL, Edwards MSB, Gutin PH, Wilson CB (1990) Cryptic vascular malformations of the spinal cord: diagnosis by magnetic resonance imaging and outcomne after surgery. J Neurosurg 72:403–407
Bergstrand A, Höök O, Lidvall H (1964) Vascular malformations of the spinal cord. Acta Neurol Scand 40:169–183
Bicknell JM, Carlow TJ, Kornfeld M, Stovring J, Turner P (1978) Familial cavernous angiomas. Arch Neurol 35:746–749
Cosgrove GR, Bertrand G, Fontaine S, Robitaille Y, Melanson D (1988) Cavernous angiomas of the spinal cord. J Neurosurg 68:31–36
Fahlbusch R, Strauss C, Huk W, Röckelein G, Kömpf D, Ruprecht KW (1990) Surgical removal of pontomesencephalic cavernous hemangiomas. Neurosurgery 26:449–457
Foix C, Alajouanine T (1926) La myélite nécrotique subaigue. Rev Neurol (Paris) II:1–42
Giombini S, Morello G (1978) Cavernous angiomas of the brain: account of fourteen personal cases and review of the literature. Acta Neurochir (Wien) 40:61–82
Goran A, Carlson DJ, Fisher FG (1964) Successful treatment of intramedullary angioma of the cord. J Neurosurg 21:311–314
Hadlich R (1903) Ein Fall von Tumor cavernosus des Rückenmarks mit besonderer Berücksichtigung der neueren Theorien über die Genese des Cavernoms. Virchows Arch [A] 172:429–441
Heimberger K, Schnabert G, Koos W, Pendl G, Auff E (1982) Spinal cavernous haemangioma (intradural-extramedullary) underlying repeated subarachnoid haemorrhage. J Neurol 226:289–293
Imakita S, Nishimura T, Yamada N, Naito HG, Takamiya M, Yamada Y, Kikuchi H, Yonekawa Y, Sawada T, Yamaguchi T (1989) Cerebral vascular malformations: applications of magnetic resonance imaging to differential diagnosis. Neuroradiology 31:320–325
Kitahara T, Miyasaka Y, Ohwada T, Yada K, Mera H (1982) An operated case of cervical spontaneous hematomyelia. Neurol Surg 10:675–679
Krayenbühl H, Yasargil MG (1963) Die Varikosis spinalis und ihre Bedeutung. Schweiz Arch Neurol Psychiatr 92:74–92
Lemme-Plaghos L, Kucharzcyck W, Brandt-Zawatzki M, Uske A, Edwards M, Norman D, Newton TH (1986) MR imaging of angiographically occult vascular malformations. AJNR 7:217–222
Lindboe CF, Nordal HJ (1985) Multiple neurilemmoma of the cauda equina, cavernous hemangioma of the spinal cord and degeneration of the lateral corticospinal tracts in a man with the clinical diagnosis of multiple sclerosis. Clin Neuropathol 4:260–264
Lobato RD, Perez C, Rivas JJ, Cordobes F (1988) Clinical, radiological and pathological spectrum of angiographically occult intracranial vascular malformations. Analysis of 21 cases and review of the literature. J Neurosurg 68:518–531
McCormick WF, Nofzinger JD (1966) “Cryptic” vascular malformations of the central nervous system. J Neurosurg 24:865–875
McCormick PC, Michelsen WJ, Post KD, Carmel PW, Stein BM (1988) Cavernous malformations of the spinal cord. Neurosurgery 23:459–463
Ondra SL, Doty JR, Mahla ME (1988) Surgical excision of a cavernous hemangioma of the rostral brain stem. Case report. Neurosurgery 23:490–493
Ortner WD, Kubin H, Pilz P (1973) Ein zervikales kavernöses Angiom. Fortschr Roentgenstr 118:475–476
Pia HW, Djindjian R (eds) (1978) Spinal angiomas: advances in diagnosis and therapy. Springer, New York Berlin Heidelberg
Pozzati E, Giuliani G, Nuzzo G, Poppi M (1989) The growth of cerebral cavernous angiomas. Neurosurgery 25:92–96
Ramos F Jr, Toffol B de, Jan M (1990) Hydrocephalus and cavernoma of the cauda equina. Neurosurgery 27:139–142
Rigamonti D, Drayer B, Johnson PC, Hadley MN, Zabramski J, Spetzler RF (1987) The MRI appearance of cavernous malformations (angiomas). J Neurosurg 67:518–524
Rigamonti D, Hadley MN, Drayer BP, Johnson PC, Hoenig-Rigamonti K, Knight JT, Spetzler RF (1988) Cerebral cavernous malformations: incidence and familial occurrence. N Engl J Med 319:343–347
Rutka JT, Brant-Zawatzki M, Wilson CB (1988) Familial cavernous malformations. Diagnostic potential of magnetic resonance imaging. Surg Neurol 29:467–474
Saito N, Yamakawa K, Sasaki T, Saito I, Takakura K (1989) Intramedullary cavernous angioma with trigeminal neuralgia: a case report and review of the literature. Neurosurgery 25:97–101
Schröder JM, Brunngraber CV (1964) Über ein intramedulläres cavernöses Angiom. Acta Neurochir (Wien) 12:632–641
Schultze F (1912) Weiterer Beitrag zur Diagnose und operativen Behandlung von Geschwülsten der Rückenmarkshäute und des Rückenmarks. Erfolgreiche Operation eines intramedullären Tumors. Dtsch Med Wochenschr 36:1676–1679
Simard JM, Garcia-Bengochea F, Ballinger WE, Mickle JP, Quisling RG (1986) Cavernous angioma: a review of 126 collected and 12 new clinical cases. Neurosurgery 18:162–172
Turner OA, Kernohan JW (1949) Vascular malformations and vascular tumors involving the spinal cord. A pathological study of 46 cases. Arch Neurol Psychiatr 46:444–463
Tyndel FJ, Bilboa JM, Hudson AR, Colapinto EV (1985) Hemangioma calcificans of the spinal cord. Can J Neurol Sci 12:321–323
Ueda S, Saito AA, Inomori S, Kim I (1987) Cavernous angioma of the cauda equina producing subarachnoid hemorrhage: case report. J Neurosurg 66:134–136
Vaquero J, Martinez R, Martinez P (1988) Cavernomas of the spinal cord: report of two cases. Neurosurgery 22:143–144
Vaquero J, Salazar J, Martinez R, Martinez P, Bravo G (1987) Cavernomas of the central nervous system: clinical syndromes, CT-diagnosis and prognosis after surgical treatment in 25 cases. Acta Neurochir (Wien) 85:29–33
Villani RM, Arienta C, Caroli M (1989) Cavernous angiomas of the central nervous system. J Neurol Sci 33:229–252
Vraa Jensen G (1949) Angioma of the spinal cord. Acta Psychiatr Neurol Scand 24:709–721
Wood MW, White RJ, Kernohan JW (1957) Cavernous hemangiomatosis involving the brain, spinal cord, heart, skin and kidney: report of case. Proc Staff Meet Mayo Clin 32:249–254
Yoshimoto T, Suzuki J (1986) Radical surgery on cavernous angiomas of the brainstem. Surg Neurol 26:72–78
Zentner J, Hassler W, Gawehn J, Schroth G (1989) Intramedullary cavernous angiomas. Surg Neurol 31:64–68
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Mehdorn, H.M., Stolke, D. Cervical intramedullary cavernous angioma with MRI-proven haemorrhages. J Neurol 238, 420–426 (1991). https://doi.org/10.1007/BF00314647
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DOI: https://doi.org/10.1007/BF00314647