Abstract
200 stereotactic biopsies were evaluated. The validity of the intraoperative histopathological results were compared with the final diagnosis using conventional embedding and staining techniques. Further comparison between the histology of the biopsy and the post mortem or open operative findings were possible in 41 cases. Discrepancy was found in one case regarding the tumor detection, and in three cases regarding the tumor grading. The mortality in our patients was 1% and the morbidity 3%. Stereotactical biopsy had a low risk even in deep brain regions such as basal ganglia, mesencephalon, and pons. At the same time the high histologic validity makes the CT-guided stereotactical biopsy recomendable in all lesions not operated by an open resection before any conservative or palliative therapy is started.
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Anagnostopoulos J, M Kiessling, B Volk: Validität morphologischerh Diagnostik an stereotaktischen Hirntumorbiopsien. In: Bamberg M, H Sack (eds) Therapie primärer Hirntumoren. Zuckschwerdt Verlag München 1988
Apuzzo MLJ, PT Chandrasoma, D Cohen et al: Computed imaging stereotaxy: experience and perspective related to 500 procedures applied to brain masses. Neurosurgery 20 (1987) 930–937
Backlund EO: A new instrument for stereotactic brain tumor biopsy. Acta Chir Scand 137 (1971) 825–827
Birg W, F Mundinger: Direct target point determination for stereotactic brain operations from CT data and the calculation of setting parameters for polar coordinate stereotactic devices. Appl Neurophysiol 45 (1982) 387–395
Boetius J, M Bergström, T Greitz: Stereotaxic computerized tomography with a GE 8800 Scanner. J Neurosurg 52 (1980) 794–780
Bosch DA: Stereotactic techniques in clinical neurosurgery. Vienna Springerverlag 1986
Brown RA, T Roberts, AG Osborn: Simplified CT-guided stereotaxic biopsy. AJNR 2 (1981) 181–184
Cheek WR, JM Taveras: Thalamic tumors. J Neurosurg 24 (1966) 505–512
Colombo F, L Casentini, A Visona et al: Stereotactic biopsy-diagnostic problems: value of cytological and histological examinations. Zentralbl Neurochir 43 (1982) 309–313
Conway LW: Stereotaxic diagnosis and treatment of intracranial tumors including an initial experience with cryosurgery for pinealmas. J Neurosurg 38 (1973) 453–460
Daumas-Duport C, V Monsaingeon, JP N'Guyen et al: Some correlations between histological and CT aspects of cerebral gliomas contributing to the choise of significant trajectories for stereotactic biopsies. Acta Neurochir Suppl (Wien) 33 (1984) 185–194
Daumas-Duport C, G Szikla: Delimination et configuration spatiale des gliomes cerebraux. Donnees histologiques, incidences therapeutiques. Neurochirurgie 27 (1981) 273–284
De Divitiis E, R Spaziante, P Cappabianca et al: Reliability of stereotactic biopsy: a model to test the value of diagnoses obtained from small fragments of nervous system tumours. Appl Neurophysiol 46 (1983) 295–303
Edner E: Stereotaxic brain tumor biopsy — five year's experience. Proceedings of the 26th annual meeting. Acta Neurochir (Wien) 31 (1965) 261
Edner E: Stereotactic biopsy of intracranial space occupying lesions. Acta Neurochir (Wien) 57 (1981) 213–234
Friedman WA, DJ Sceats, BR Nestok et al: The incidence of unexpected pathological findings in a image-guided biopsy series. A review of 100 consecutive cases. Neurosurgery 25 (1989) 180–184
Gleason CA, B Wise, B Feinstein: Stereotactic localisation (with computerized tomographic scanning), biopsy, and radiofrequency treatment of deep brain lesions. Neurosurgery 2 (1978) 217–222
Hahn JF, WJ Levy, MJ Weinstein: Needle biopsy of intracranial lesions guided by computer tomography. Neurosurgery 5 (1979) 11–14
Hallac I, L Bakay: New instrument for brain biopsy. J Neurosurg 20 (1963) 529–530
Heath RG, S John, O Foss: Stereotaxic biopsy. A method for the study of discrete brain regions of animals and man. Arch Neurol 4 (1961) 291–300
Hitchcock E, F Sato: Treatment of malignant gliomata. J Neurosurg 21 (1964) 497–505
Hounsfield GN: Computerized transverse axial scanning (Tomography) part I. Description of system. Br J Radiol 46 (1973) 1016–1022
Housepian EM, JL Pool: The accuracy of human stereoencephalotomy as judged by histological confirmation of roentgenographic localization. J Nerv Ment Dis 130 (1960) 520–525
Housepian EM, JL Pool: Application of stereotaxic methods to histochemical electromicroscopic and electrophysiological studies of human subcortical structures. Confin Neurol 22 (1962) 171–177
Kalyanaraman S, FJ Gillingham: Stereotaxic biopsy. J Neurosurg 21 (1964) 854–858
Kelly PJ: Tumor stereotaxis. WB Saunders Company, Philadelphia 1991
Kleihues P, B Volk, J Anagnostoloulos et al: Morphologic evaluation of stereotactic brain tumour biopsies. Acta Neurochir Suppl (Wien) 33 (1984) 171–181
Leksell L, B Jernberg: Stereotaxis and tomography. A technical note. Acta Neurochir (Wien) 52 (1980) 1–7
Lobato RD, JJ Rivas: Applications of CT-adapted stereotaxis for the diagnosis and treatment of intracranial lesions. Acta Neurochir (Wien) 87 (1987) 14–21
Lunsford LD, AJ Martinez: Stereotactic exploration of the brain in the era of computed tomography. Surg Neurol 22 (1984) 222–230
Maroon JC, WO Bank, BP Drayer et al: Intracranial biopsy assisted by computed tomography. J Neurosurg 46 (1977) 740–744
Marshall LF, H Adams, D Doyle et al: The histological accuracy of the smear technique for neurosurgical biopsies. J Neurosurg 39 (1973) 82–88
Monsaingeon V, C Daumas-Duport, M Mann et al: Stereotactic sampling biopsies in a series of 268 consecutive cases — validity and technical aspects. Acta Neurochir Suppl (Wien) 33 (1984) 195–200
Ostertag CB, HD Mennel, M Kiessling: Stereotactic biopsy of brain tumors. Surg Neurol 14 (1980) 275–283
Ostertag CB: Reliability of stereotactin brain tumor biopsy. In: Lunsford LD (ed): Modern stereotactic neurosurgery. Martinus Nijhoff Boston-Dordrecht, Lancaster 1988
Pecker J, JM Scarabin, B Vallee et al: Treatment in tumours of the pineal region: Value of stereotaxic biopsy. Aurg Neurol 12 (1979) 341–348
Pecker J, J Simon, JM Scarabin et al: Application des methodes stereotaxiques au diagnostic neuroradiologiques. Neurochirurgie 20 (1973) 5–20
Penn RD, WW Whisler, CA Smith et al: Stereotactic surgery with image processing of computerized tomographic scanns. Neurosurgery 3 (1978) 157–163
Piscun WA, EA Stevens, JR LaMorgese et al: A simplified method of CT assisted localization and biopsy of intracranial lesions. Surg Neurol 11 (1979) 413–417
Pool JL, RP Kamrin: The treatment of intracranial gliomas by surgery and radiation. Progr Neurol Surg Vol 1. Karger, Basel-New York 1966
Rand RW, G Heuser, A Dashe et al: Stereotactic transsphenoidal biopsy and cryosurgery of pitutitary tumors. AJR 105 (1969) 273–286
Riechert T, MA Gisinger, E Mölbert: Biopsien während stereotaktischer Operationen beim Parkinsonsyndrom. Neurochirurgia 10 (1967) 106–118
Rushworth RG: Stereotactic guided biopsy in the computerized tomographic scanner. Surg Neurol 14 (1980) 451–454
Scarabin JM, J Pecker, JM Brucher et al: Stereotaxic exploration in 200 supratentorial brain tumors: Its value in addition to computerized tomography. Neuroradiol 16 (1978) 591–593
Scarabin JM, J Pecker, B Vallee et al: Stereotaxic exploration and biopsy of tumors in the region of the tentorial hiatus. J Neuroradiol 5 (1978) 57–68
Scerrati M, GF Rossi: The reliability of stereotactic biopsy. Acta Neurochir Suppl (Wien) 33 (1984) 201–205
Sedan R, JC Peragut, P Villicioni: Presentation d'un appareillage original pour biopsie cerebrale et tumorale en condition stereotactique. Communication a la societe de neurochirurgie de lange francaise 1975
Shetter AG, TV Bertuccini, HW Pittmann: Closed needle biopsy in the diagnosis of intracranial mass lesions. Surg Neurol 8 (1977) 341–345
Thomas DGT, RM Nouby: Experience in 300 cases of CT-directed stereotactic surgery for lesion biopsy and aspiration of haematoma. Br J Neurosurg 3 (1989) 321–326
Ungersböck K, A Budka, M Scmidbauer et al: Stereotactische Biopsie intracranieller Prozesse: Validität der histologischen Diagnostik. Wiener Klin Wschr 101 (1989) 376–380
Ungersböck K, P Gruner, J Bohl, W Müller-Forell et al: CT-guided stereotactic biopsy aided by doppler ultrasonic vascular monitoring. Acta Neurochirurgica 115 (1992) 152–155
Waltregny A, V Petrov, J Brotchi: Serial stereotaxic biopsies. Acta Neurochir Suppl (Wien) 21 (1974) 221–226
Wester K, O Sortland, E Hauglie-Hansen: A simple and inexpensive method for CT-guided stereotaxy. Neuroradiol 20 (1981) 255–256
Willems JGNS, JM Alva-Willems: Accuracy of cytologic diagnostic of central nervous system neoplasms in stereotactic biopsies. Acta Cytol (Baltimore) 28 (1984) 243–248
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Grunert, P., Ungersböck, K., Bohl, J. et al. Results of 200 intracranial stereotactic biopsies. Neurosurg. Rev. 17, 59–66 (1994). https://doi.org/10.1007/BF00309989
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DOI: https://doi.org/10.1007/BF00309989