Skip to main content
SpringerLink
Log in

Myocardial fatty acid homeostasis

  • Invited Paper
  • Published:
Molecular and Cellular Biochemistry Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Bing RJ, Siegel A, Ungar I, Gilbert M: Metabolism of the human heart II. Studies on fat, ketone and aminoacid metabolism. Am J Med 16: 504–515, 1954

    Google Scholar 

  2. Ballard FB, Danforth WH, Naegle S, Bing RJ: Myocardial metabolism of fatty cids. J Clin Invest 39: 717–723, 1960

    Google Scholar 

  3. Spector AA: Plasma lipid transport. Clin Physiol Biochem 2:123–134, 1984

    Google Scholar 

  4. Stam H, Hülsmann WC: Regulation of lipases involved in the supply of substrate fatty acids for the heart. Eur Heart J 6: 158–167, 1985

    Google Scholar 

  5. Stam H, Schoonderwoerd K, Breeman WAP, Hülsmann WC: Effect of hormones, fasting, diabetes on triglyceride lipase activities in rat heart and liver. Horm Metab Res 16: 293–297, 1984

    Google Scholar 

  6. Cryer A: The role of the endothelium in myocardial lipoprotein dynamics. Mol Cell Biochem, This issue

  7. Van der Vusse GJ, Little SE, Bassingthwaighte JB: Transendothelial transport of arachidonic and palmitic acid in the isolated rabbit heart. J Mol Cell Cardiol 19 (suppl III): 100, 1987

    Google Scholar 

  8. Bassingthwaighte, JB, Noodleman L, Van der Vusse GJ, Glatz JFC: Modeling of palmitate transport in the heart. Mol Cell Biochem, this issue

  9. Fujii S, Kawaguchi H, Yasuda H: Purification of high-affinity fatty acid receptors in rat myocardial sarcolemmal membranes. Lipids 22: 544–546, 1987

    Google Scholar 

  10. Stremmel W: Transmembrane transport of fatty acids in the heart. Mol Cell Biochem 88: 23–29, 1989

    Google Scholar 

  11. Glatz JFC, Van der Vusse GJ, Veerkamp JH: Fatty acid-binding proteins and their physiological significance. News Physiol Sci 3: 41–43, 1988

    Google Scholar 

  12. Fournier NC, Rahim M: Control of energy production in the heart: a new function of fatty acid binding protein. Biochemistry 24: 2387–2396, 1985

    Google Scholar 

  13. Murthy MSR, Pande SV: Malonyl-CoA binding site and the overt carnitine palmitoyltransferase activity reside on the opposite sides of the outer mitochondrial membrane. Proc Natl Acad Sci USA 84: 378–382, 1987

    Google Scholar 

  14. Shipp JC, Thomas JM, Crevasse L: Oxidation of carbon-14-labeled endogenous lipids by isolated perfused rat heart. Science 143: 371–373, 1964

    Google Scholar 

  15. Van Bilsen M, Engels W, Van der Vusse GJ, Reneman RS: Significance of myocardial eicosanoid production. Mol Cell Biochem, this issue

  16. De Chaffoy de Courcelles D: Is there evidence of a role of the phosphoinositol-cycle in the myocardium. Mot Cell Biochem, this issue

  17. Post JA, Langer GA, Op den Kamp JAF, Verkley AJ: Phospholipid asymmetry in cardiac sarcolemma. Analysis of intact cells and gas-dissected membranes. Biochim Biophys Acta 943: 256–266, 1988

    Google Scholar 

  18. Scherrer LA, Gross RW: Subcellular distribution, molecular dynamics and catabolism of plasmalogens in myocardium. Mol Cell Biochem, this issue

  19. Nalbone G, Hostetler KY: Subcellular localization of the phospholipase A of rat hearts. Evidence for a cytosolic phospholipase A1. J Lipid Res 26: 104–114, 1985

    Google Scholar 

  20. Weglicki WB, Low MG: Phospholipases of the myocardium. Basic Res Cardiol 82 (suppl 1): 107–112, 1987

    Google Scholar 

  21. Miyazaki Y, Gross RW, Sobel BE, Saffitz JE: Biochemical and subcellular distribution of arachidonic acid in rat myocardium. Am J Physiol 253: C846-C853, 1987

    Google Scholar 

  22. Van der Vusse GJ, Prinzen FW, Van Bilsen M, Engels W, Reneman RS: Accumulation of lipids and lipid-intermediates in the heart during ischaemia. Basic Res Cardiol 82 (suppl 1): 157–167, 1987

    Google Scholar 

  23. Rosamund TL, Abendschein DR, Sobel BE, Bergmann SR, Fox KAA: Metabolic fate of radiolabeled palmitate in ischemic canine myocardium: implications for positron emission tomography. J Nucl Med 28: 1322–1329, 1987

    Google Scholar 

  24. Van der Vusse GJ, Roemen ThHM, Prinzen FW, Coumans WA, Reneman RS: Uptake and tissue content of fatty acids in dog myocardium under normoxic and ischemic conditions. Circ Res 50: 538–546, 1982

    Google Scholar 

  25. Chien KR, Han A, Sen A, Buja LM, Willerson JT: Accumulation of unesterified arachidonic acid in ischaemic canine myocardium. Circ Res 54: 313–322, 1984

    Google Scholar 

  26. Van Bilsen M, Engels W, Willemsen PHM, Coumans WA, Van der Vusse GJ, Reneman RS: Arachidonic acid accumulation and eicosanoid synthesis during ischaemia and reperfusion in isolated rat hearts. Prog Appl Microcirc 12: 236–243, 1987

    Google Scholar 

  27. Trach V, Buschmans-Denkel E, Schaper W: Relation between lipolysis and glycolysis during ischemia in the isolated rat heart. Basic Res Cardiol 81: 454–464, 1986

    Google Scholar 

  28. Van Bilsen M, Van der Vusse GJ, Willemsen PHM, Coumans WA, Roemen ThHM, Reneman RS: Lipid alterations in isolated, working rat hearts during ischemia and reperfusion: its relation to myocardial damage. Circ Res 64: 304–314, 1989

    Google Scholar 

  29. Schoonderwoerd K, Van der Kraaij T, Hulsmann WC, Stam H: Hormones and triacylglycerol metabolism under normoxic and ischemic conditions. Mol Cell Biochem, this issue

  30. Schoonderwoerd K, Broekhoven-Schokker, Hülsmann WC, Stam H: Involvement of lysosome-like particles in the metabolism of endogenous triglycerides in the normoxic and ischemic rat heart. Uptake and degradation of triglyceride by lysosomes isolated from rat hearts. Basic Res Cardiol, 1989, in press

  31. Van der Vusse GJ, Van Bilsen M, Reneman RS: Is phospholipid degradation a critical event in ischemia and reperfusion induced damage? News in Physiol Sci, 1989, in press

  32. Jennings RB, Reimer KA, Steenbergen C: Myocardial ischernia revisited: the osmolar load, membrane damage and reperfusion. J Mol Cell Cardiol 18: 769–780, 1986

    Google Scholar 

  33. Verkley A, Post JA: Physico-chemical properties and organization of lipids in membranes: their possible role in myocardial injury. Basic Res Cardiol 82 (suppl 1): 85–91, 1987

    Google Scholar 

  34. Huang XQ, Liedtke AJ: Alterations in fatty acid oxidation in ischemic and reperfused myocardium. Mol Cell Biochem, this issue

  35. Lopaschuk GD, McNeil GF, Mc Veigh JJ: Glucose oxidation is stimulated in reperfused ischemic hearts with the carnitine palmitoyl transferase 1 inhibitor, Etoxomir. Mol Cell Biochem, this issue

  36. Liedtke AJ, Demaison L, Nellis SH: Effects of L-propionylcarnitine on mechanical recovery during reflow in intact hearts. Am J Physiol 255: 169–176, 1988

    Google Scholar 

  37. Bergmann SR: Clinical applications of assessments of substrate utilization with positron emission tomography. Mol Cell Biochem, this issue

  38. Schelbert HR, Henze E, Schon HR, Keen R, Hansen H, Selin C, Huang S-C, Barrio JR, Phelps ME: C-11 palmitate for noninvasive evaluation of regional myocardial fatty acid metabolism with positron computed tomography III. Am Heart J 105: 492–504, 1983

    Google Scholar 

  39. Visser FC, Van Eenige MJ, Westera G, Den Hollander W, Duwel CMB, Van der Wall EE, Heidendal GAK, Roos JP: Metabolic fate of radioiodinated heptadecanoic acid in the normal canine heart. Circulation 72: 565–572, 1985

    Google Scholar 

  40. Van der Vusse GJ, Reneman RS: The myocardial non-esterified fatty acid controversy. J Mol Cell Cardiol 16: 677–682, 1984

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Dept. of Physiology, University of Limburg, Maastricht, The Netherlands

    Ger J. van der Vusse & Jan F. C. Glatz

  2. Dept. of Biochemistry I, Erasmus University, Rotterdam, The Netherlands

    Hans C. G. Stam

Authors
  1. Ger J. van der Vusse
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Jan F. C. Glatz
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Hans C. G. Stam
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

van der Vusse, G.J., Glatz, J.F.C. & Stam, H.C.G. Myocardial fatty acid homeostasis. Mol Cell Biochem 88, 1–6 (1989). https://doi.org/10.1007/BF00223416

Download citation

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00223416

Key words

Search

Navigation