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High bladder cancer mortality in rural New England (United States): An etiologic study

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An interview study of next-of-kin of 325 persons who died of bladder cancer and 673 individuals who died of other causes in Vermont and New Hampshire (United States) was conducted to assess reasons for the persistent pattern of elevated bladder cancer mortality for both genders in rural New England. There was some evidence of elevated risks for both leather and textile workers that rose to over twofold for workers who also lived near these industries and for persons with French-Canadian ancestry. Occupational exposures in the textile and leather industry may explain at least a portion of the excess bladder cancer risk in rural New England.

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References

  1. Mason TJ, McKay FW. U.S. Cancer Mortality by County: 1950–1969. Washington, DC: US Government Printing Office, 1974; DHEW Pub. No. (NIH) 74–615.

    Google Scholar 

  2. Blot WJ, Fraumeni JFJr. Geographic pattern of bladder cancer in the United States. JNCI 1978; 61: 1017–23.

    Google Scholar 

  3. Hoar SK, Hoover R. Truck driving and bladder cancer mortality in rural New England. JNCI 1985; 74: 771–4.

    Google Scholar 

  4. Hirono I. Recent advances in research on bracken carcinogen and carcinogenicity of betel nut. J Environ Sci Health 1985; C 3(2): 145–87.

    Google Scholar 

  5. World Health Organization. International Classification of Diseases, Eighth Revision. Geneva, Switzerland: WHO, 1967.

    Google Scholar 

  6. World Health Organization. International Classification of Diseases, Ninth Revision. Geneva, Switzerland: WHO, 1977.

    Google Scholar 

  7. Office of Management and Budget. Standard Industrial Classification Manual. Washington, DC: US Government Printing Office, 1972.

    Google Scholar 

  8. US Department of Commerce. Standard Occupational Classification Manual. Washington, DC: USDC Office of Federal Statistical Policy and Standards., 1977.

    Google Scholar 

  9. Breslow NE, Day NE. Statistical Methods in Cancer Research. Vol I. Analysis of Case-Control Studies. Lyon, France; International Agency for Research in Cancer, 1980; IARC Sci. Pub. No. 32: 192–246.

    Google Scholar 

  10. Dixon WJ, Brown MB, Engelmen L, Jennrich RI, eds. BMDP Statistical Software Manual, Volume 2. Berkeley, CA (USA): University of California Press, 1990: 1013–45.

    Google Scholar 

  11. Whittemore AS: Estimating attributable risk from casecontrol studies. Am J Epidemiol 1983; 117: 76–85.

    Google Scholar 

  12. Boice JD, Lubin JH, Preston DL. Epidemiologic Analysis with a Personal Computer (EPITOME). Bethesda, MD (USA): National Institutes of Health, 1992: DHHS Pub. No. (NIH)91–3180.

    Google Scholar 

  13. Fraumeni JFJr. Etiologic insights from cancer mapping. In: Miller RW, Watanabe S, Fraumeni JFJr., et al, eds. Unusual Occurrences As Clues To Cancer Etiology. London, UK: Taylor & Francis Ltd., 1988: 13–25.

    Google Scholar 

  14. Pickle LW, Mason TJ, Howard N, Hoover R, Fraumeni JFJr. Atlas of U.S. Cancer Mortality Among Whites: 1950–1980. Washington, D.C.: US Government Printing Office, 1987; DHHS Pub. No. (NIH) 87–2900.

    Google Scholar 

  15. Blot WJ, Harrington M, Toledo A, Hoover R, Heath CWJr, Fraumeni JFJr. Lung cancer after employment in shipyards during World War II. N Engl J Med 1978; 299: 620–4.

    Google Scholar 

  16. Blot WJ, Morris LE, Stroube R, Tagnon I, Fraumeni JFJr. Lung and laryngeal cancers in relation to shipyard employment in coastal Virginia. JNCI 1980; 65: 571–5.

    Google Scholar 

  17. Blot WJ, Davies JE, Brown LM, et al Occupation and the high risk of lung cancer in northeast Florida. Cancer 1982; 50: 364–71.

    Google Scholar 

  18. Winn DM, Blot WJ, Shy CM, Pickle LW, Toledo A, Fraumeni JFJr. Snuff dipping and oral cancer among women in the southern United States. N Engl J Med 1981; 304: 745–9.

    Google Scholar 

  19. Silverman DT, Hartge P, Devesa SS. Epidemiology of bladder cancer. In: Devita VTJr, Hellman S, Rosenberg SA, eds. Cancer Prevention. Philadelphia, PA (USA): J.B. Lippincott Co., 1993.

    Google Scholar 

  20. Dublin T. Transforming Women's Work: New England Lives in the Industrial Revolution. Ithaca, NY (USA): Cornell University Press, 1994: 77, 119–25.

    Google Scholar 

  21. Silverman DT, Levin LI, Hoover RN. Occupational risks of bladder cancer among white women in the United States. Am J Epidemiol 1990; 132: 453–61.

    Google Scholar 

  22. Robinson CF, Waxweiler RJ, Fowler DP. Mortality among production workers in pulp and paper mills. Scand J Work Environ Health 1986; 12: 552–60.

    Google Scholar 

  23. Silverman DT, Hoover RN, Mason TJ, Swanson GM. Motor exhaust-related occupations and bladder cancer. Cancer Res 1986; 46: 2113–6.

    Google Scholar 

  24. McLaughlin JK, Blot WJ, Mehl E, Mandel JS. Problems in the use of dead controls in case-control studies. II. Effect of excluding certain causes of death. Am J Epidemiol 1985; 122: 485–94.

    Google Scholar 

  25. Nelson LM, Longstreth WT, Koepsell TD, van Belle G. Proxy respondents in epidemiologic research. Epidemiol Rev 1990; 12: 71–86.

    Google Scholar 

  26. Silverman DT, Levin LI, Hoover RN, Hartge P. Occupational risks of bladder cancer in the United States: I. White men. JNCI 1989; 81: 1472–80.

    Google Scholar 

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Brown, L.M., Zahm, S.H., Hoover, R.N. et al. High bladder cancer mortality in rural New England (United States): An etiologic study. Cancer Causes Control 6, 361–368 (1995). https://doi.org/10.1007/BF00051412

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