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Genetics and Molecular Signature of Gastric Cancer

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Personalized Management of Gastric Cancer

Abstract

Gastric cancer (GC) is a major contributor to the global cancer burden. According to GLOBOCAN 2012, approximately 952,000 new cases of gastric cancer were diagnosed globally in 2012 (representing 6.8% of total cancer diagnoses), and 723,000 patients died as a result of gastric cancer (representing 8.8% of all cancer-related deaths) [1]. These statistics make gastric cancer the fifth most common malignant tumor in the world, behind cancers of the lung, breast, colon, rectum, and prostate. Of these cases, more than 70% occurred in developing countries, and half the total were diagnosed in Eastern Asia (with China reporting approximately 43%) [1]. Encouragingly, numerous studies have demonstrated a decrease in the incidence of gastric cancer over the past few decades [2–4]. Nevertheless, the total number of new gastric cancer cases has risen in recent years as a result of population growth and changing demographics.

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Authors and Affiliations

  1. Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, 211166, China

    Meng Zhu & Guangfu Jin

  2. Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Medicine, Nanjing Medical University, Nanjing, 211166, China

    Meng Zhu & Guangfu Jin

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  1. Meng Zhu
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  2. Guangfu Jin
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Correspondence to Guangfu Jin .

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Editors and Affiliations

  1. The Comprehensive Cancer Center Drum Tower Hospital, Medical School of Nanjing University, Nanjing, Jiangsu, China

    Jia Wei

  2. The Comprehensive Cancer Center Drum Tower Hospital, Medical School of Nanjing University, Nanjing, Jiangsu, China

    Baorui Liu

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© 2017 Springer Nature Singapore Pte Ltd.

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Zhu, M., Jin, G. (2017). Genetics and Molecular Signature of Gastric Cancer. In: Wei, J., Liu, B. (eds) Personalized Management of Gastric Cancer. Springer, Singapore. https://doi.org/10.1007/978-981-10-3978-2_2

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  • DOI: https://doi.org/10.1007/978-981-10-3978-2_2

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