Abstract
Although colour vision defects are quite common in optic neuritis and multiple sclerosis, there is a lack of general agreement as to the nature of the colour vision defect associated with demyelinating diseases. We investigated whether there is selective involvement of particular channels in demyelinating disease by recording visually evoked cortical potentials (VEPs) elicited by grating patterns that selectively stimulate the chromatic pathways. This paper contains preliminary results on a small number of patients who have essentially recovered from or have suffered no spatial vision loss. None of these patients showed S cone pathway deficits; all deficits involved pathways with L or M cone input.
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Crognale M.A., Switkes E., Rabin J., Schneck M.E., Haegerstrom-Portnoy G. and Adams A.J. (1993). Application of the spatio-chromatic visual evoked potential to detection of congenital and acquired colour-vision deficiencies. J. Opt. Soc. Am. Am. 10:1818–1825
Dain S.J., Rammohan K.W., Benes S.C. and King-Smith RE. (1990). Chromatic, spatial, and temporal losses of sensitivity in multiple sclerosis. Invest. Ophthalmol. Vis. Sci. 31:548–558
Fallowfield L. and Krauskopf J. (1984). Selective loss of chromatic sensitivity in demyelinating disease. Invest. Ophthalmol. Vis. Sci. 25:771–773
Fleishman J.A., Beck R.W., Linares O.A. and Klein J.W. (1987). Deficits in visual function after resolution of optic neuritis. Ophthalmology 94:1029–1035
François J. and Verriest G. (1957). Les dyschromatopsies acquises. Ann. Oculist (Paris) 190:713–746
Franois J. and Verriest G. (1968). Nouvelles observations de deficincies acquises de la discrimination chromatique. Ann. Oculist (Paris) 201:1097–1114
Griffin J.F. and Wray S.H. (1978). Acquired colour vision defects in retrobulbar neuritis. Am. J. Ophthalmol. 86:193–201
Harrison A.C., Becker W.J. and Stell W.K. (1987). Colour vision abnormalities in multiple sclerosis. Can. J. Neurol. Sci. 14:279–285
Krauskopf J., Williams D.R. and Heeley D.W. (1982). Cardinal directions of colour space. Vision Res. 22:1123–1131
MacLeod D.I.A. and Boynton R.M. (1978). Chromaticity diagram showing cone excitation by stimuli of equal luminance. J. Opt. Soc. Am. 69:1183–1186
Marré M. (1970). Die Darstellung von drei Farbseh-Mechanismen bei erworbenen Farbenseh-störungen. Colour 69, 97–104
Mullen K.T. and Plant G.T. (1986). Colour and luminance vision in human optic neuritis. Brain. 109:1–13
Ohta Y. (1970). Studies on acquired anomalous colour vision. Colour vision anomalies in patients with lesions of the retina, optic chiasma and post-occipital centre. Colour 69:88–96
Optic Neuritis Study Group (1991). The clinical profile of optic neuritis. Arch. Ophthalmol. 109: 1673–1678
Rabin J., Switkes E., Crognale M., Schneck M.E. and Adams A.J. (1994). Visual evoked potentials in three-dimensional colour space: correlates of spatio-chromatic processing. Vision Res. 34:2657–2671
Russell M.H.A., Murray I.J., Metcalfe R.A. and Kulikowski J.J. (1991). The visual defect in multiple sclerosis and optic neuritis. A combined psychophysical and electrophysiological investigation. Brain 114: 2419–2435
Schneck M.E., Haegerstrom-Portnoy G., Katz B., Brabyn J.A., Fusaro R. and Beck R. (1994). Color vision in optic neuritis: Findings in ONTT participants. Invest. Ophthalmol. Vis. Sci. (Suppl.) 35: 1754
Travis D. and Thompson P. (1989). Spatiotemporal contrast sensitivity and colour vision in multiple sclerosis. Brain 112: 283–303
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© 1997 Springer Science+Business Media Dordrecht
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Schneck, M.E., Lee, E., Fortune, B., Crognale, M., Adams, A.J., Switkes, E.W. (1997). Spatio-chromatic VEPS in recovered optic neuritis and multiple sclerosis. In: Cavonius, C.R. (eds) Colour Vision Deficiencies XIII. Documenta Ophthalmologica Proceedings Series, vol 59. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-5408-6_18
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DOI: https://doi.org/10.1007/978-94-011-5408-6_18
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