Abstract
Cancer clinical trials focus upon the evaluation of such biomedical outcomes as duration of survival, retardation of the disease process and control of major physical symptoms (Buyse et al. 1984; Friedman et al. 1985). In recent years, however, these clinical end points have been criticized for a lack of comprehensiveness (Greer 1984; Greer and Silberfarb 1982). Following the lead of the WHO in defining health as complete physical, mental and social well-being, the scope of investigation has been extended to include assessment of a range of psychosocial variables that can be subsumed under the heading “quality of life.”
The research described in this paper is a project of the EORTC Study Group on Quality of Life (protocol 15861). The study coordinator is N. K. Aaronson. The national coordinators are: P.B.C.Rofe (Australia), B.Pfausler (Austria), D.Razavi (Belgium), D.Osoba (Canada), M. Bullinger (Federal Republic of Germany), S. Schraub (France), S. Ahmedzai (United Kingdom), A.Filiberti (Italy), F.Takeda (Japan), J.C.J.M. de Haes (the Netherlands), S. Kaasa (Norway), J. Estape (Spain), M. Sullivan (Sweden), J. Bernhard (Switzerland), and M.Mastilica (Yugoslavia). O.Dalesio and D.Crabeels are, respectively, the EORTC Data Center statistician and data manager associated with the project.
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Aaronson, N.K., Bullinger, M., Ahmedzai, S. (1988). A Modular Approach to Quality-of-Life Assessment in Cancer Clinical Trials. In: Scheurlen, H., Kay, R., Baum, M. (eds) Cancer Clinical Trials. Recent Results in Cancer Research, vol 111. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83419-6_27
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DOI: https://doi.org/10.1007/978-3-642-83419-6_27
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