Skip to main content
SpringerLink
Log in

Abortive Adenovirus Infection and Host Range Determinants

  • Chapter
The Molecular Repertoire of Adenoviruses I

Part of the book series: Current Topics in 199/I Microbiology and Immunology ((CT MICROBIOLOGY,volume 199/1))

Abstract

The host range of a virus constitutes at one level the distribution of host organisms that it infects and at another level the tissues in that host that are targeted by the virus. Host range is determined by properties of both the virus and the potential host cell, due to the obligate parasitic nature of viruses. The expression of cell surface receptors for virus strongly correlates with susceptibility of the cell to infection, and cells that do not allow virus to bind are necessarily resistant. Thus host range is initially determined by the presence or absence of the appropriate interaction between extracellular host range determinants that are the virus attachment protein and the host receptor. Broad host range viruses generally bind to common molecules on the cell surface; for example, influenza binds to sialic acid-containing carbohydrates on cellular glycoproteins or glycolipids. Narrow host range viruses typically bind with high affinity to a specific protein, as exemplified by the binding of rhinovirus, poliovirus, and human immunodeficiency virus (HIV) to specific members of the human immunoglobulin super family. Cell surface interactions are not the only determinants of host range, however. Cells that support all steps in multiplication of a virus are termed permissive (with maximum virus yields) or semipermissive (with less than maximum virus yields). Nonpermissive cells allow virus to bind but do not allow complete virus multiplication, and the subsequent abortive infection is caused by the block of one or more multiplication steps at the intracellular level.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Anderson CW, Hardy MM, Dunn JJ, Klessig DF (1983) Independent, spontaneous mutants of adenovirus type 2-simian virus 40 hybrid Ad2+ND3 that grow efficiently in monkey cells possess identical mutations in the adenovirus type 2 DNA-binding protein gene. J Virol 48: 31–39

    PubMed  Google Scholar 

  • Anderson KP, Wong EA, Klessig DF (1985) Microinjection of mRNA enhances the translational efficiency of human adenovirus fiber message in monkey cells. Mol Cell Biol 5: 2870–2873

    CAS  PubMed  Google Scholar 

  • Aneskievich BA, Taichman LB (1988a) Epithelium-specific response of cultured keratinocytes to infection with adenovirus type 2. J Invest Dermatol 91: 309–314

    Article  CAS  PubMed  Google Scholar 

  • Aneskievich BA, Taichman LB (1988b) Evidence for two points of restriction in the expression of adenovirus type 2 in cultured epidermal keratinocytes. J Virol 62: 4365–4368

    CAS  PubMed  Google Scholar 

  • Angeletti PC (1992) Adenovirus 12 abortive infection: interactions of the E1A upstream region with permissive and nonpermissive cell protein. Thesis, Illinois State University

    Google Scholar 

  • Biron KK, Raskas K Jr (1976) Adenovirus type 12 infection of defined mouse-human hybrid cell clones. Experientia 32: 38–40

    Article  CAS  PubMed  Google Scholar 

  • Boshart M, Gissman L, Ikenberg H, Kleinheinz A, Scheurlen W, zur Hausen H (1984) A new type of papillomavirus DNA and its presence in genital cancer biopsies and in cell lines derived from cervical cancer. EMBO J 3: 1151–1157

    CAS  PubMed  Google Scholar 

  • Bourguignon LYW, Rubin RW, Krishan A (1983) Cell cycle dependent receptor capping in mouse leukemic cells. Cell Biol Int Rep 7: 109–119

    Article  CAS  PubMed  Google Scholar 

  • Braithwaite AW, Sturzbecher H-W, Addison C, Palmer C, Rudge K, Jenkins JR (1987) Mouse p53 inhibits SV40 origin-dependent DNA replication. Nature 329: 458–460

    Article  CAS  PubMed  Google Scholar 

  • Bridge E, Hemstrom C, Pettersson U (1991) Differential regulation of adenovirus late transcriptional units by the products of early region. Virology 183: 260–266

    Article  CAS  PubMed  Google Scholar 

  • Bridge E, Medghalchi S, Ubol S, Leesong M, Ketner G (1993) Adenovirus early region 4 and viral DNA synthesis. Virology 193: 794–801

    Article  CAS  PubMed  Google Scholar 

  • Brough DE, Rice SA, Sell S, Klessig DF (1985) Restricted changes in the adenovirus DNA-binding protein that lead to extended host range or temperature-sensitive phenotypes. J Virol 55: 206–212

    CAS  PubMed  Google Scholar 

  • Brown M, Wilson-Friesen HL, Doane F (1992) A block in release of progeny virus and a high particle- to-infectious unit ratio contribute to poor growth of enteric adenovirus types 40 and 41 in cell culture. J Virol 66: 3198–3205

    CAS  PubMed  Google Scholar 

  • Brusca JS, Chinnadurai G (1983) Structure and reversion of an adenovirus type 2 mutant containing a duplication of the left end of the genome at the right end. Virology 129: 381–392

    Article  CAS  PubMed  Google Scholar 

  • Challberg MD, Kelly TJ Jr (1989) Animal virus DNA replication. Annu Rev Biochem 58: 671–717

    Article  CAS  PubMed  Google Scholar 

  • Charlton KM, Artois M, Prevec L, Campbell JB, Casey GA, Wandeier AI, Armstrong J (1992) Oral rabies vaccination of skunks and foxes with a recombinant human adenovirus vaccine. Arch Virol 123: 169–179

    Article  CAS  PubMed  Google Scholar 

  • Chowrira BM, Lucher LA (1990) Extracts of hamster cells abortively infected with human adenovirus type 12 are competent to support initiation of viral DNA replication. Virology 176: 289–291

    Article  CAS  PubMed  Google Scholar 

  • Chowrira BM, Zhao J, Lucher LA (1991) Formation in vitro of the pTP-dCMP initiation complex of human adenovirus type 12. J Gen Virol 72: 427–430

    Article  CAS  PubMed  Google Scholar 

  • Daniell E, Groff DE, Fedor MJ (1981) Adenovirus chromatin structure at different stages of infection. Mol Cell Biol 1: 1094–1105

    CAS  PubMed  Google Scholar 

  • Defer C, Belin M-T, Caillet-Boudin M-L, Boulanger P (1990) Human adenovirus-host cell interactions: comparative study with members of subgroups B and C. J Virol 64: 3661–3673

    CAS  PubMed  Google Scholar 

  • de Jong JC, Wigand R, Kidd AH, Wadell G, Kapsenberg JG, Muzerie CJ, Wermenbol AG, Firtzlaff RG (1983) Candidate adenoviruses 40 and 41: fastidious adenoviruses from human infant stool. J Med Virol 11: 215–231

    Article  PubMed  Google Scholar 

  • de La Roche Saint Andre C, Delmas V, Bastien C, Goutebroze L, Scherneck S, Feunteun J (1989) Molecular aspects of pathogenesis in hamster polyomavirus. In: Villareal LP (ed) Common mechanisms of transformation by small DNA tumor viruses. American Society for Microbiology, Washington DC, pp 225–238

    Google Scholar 

  • Delsert D, D’Halluin JC (1984) Genetic expression of human adenoviruses in simian cells. Evidence for interserotypic inhibition of viral DNA synthesis. Virus Res 1: 365–380

    Article  CAS  PubMed  Google Scholar 

  • Dery CV, Toth M, Brown M, Horvath J, Allaire S, Weber JM (1985) The structure of adenovirus chromatin in infected cells. J Gen Virol 66: 2671–2684

    Article  CAS  PubMed  Google Scholar 

  • Dimmock NJ (1982) Initial stages in infection with animal viruses. J Gen Virol 59: 1–22

    Article  CAS  PubMed  Google Scholar 

  • Doerfler W (1970) Integration of the deoxyribonucleic acid of adenovirus type 12 into the deoxyribonucleic acid of baby hamster kidney cells. J Virol 6: 652–666

    CAS  PubMed  Google Scholar 

  • Doerfler W (1991) Abortive infection and malignant transformation by adenoviruses: integration of viral DNA and control of viral gene expression by specific patterns of DNA methylation. Adv Virus Res 39: 89–128

    Article  CAS  PubMed  Google Scholar 

  • Doerfler W, Lundholm U (1970) Absence of replication of the DNA of adenovirus type 12 in BHK 21 cells. Virology 40: 754–757

    Article  CAS  PubMed  Google Scholar 

  • Doerfler W, Lundholm U, Hirsch-Kauffmann M (1972) Intracellular forms of adenovirus deoxyribonucleic acid. I. Evidence for a deoxyribonucleic acid-protein complex in baby hamster kidney cells infected with adenovirus type 12. J Virol 9: 297–308

    CAS  PubMed  Google Scholar 

  • Dornreiter I, Höss A, Arthur AK, Fanning E (1990) SV40 T antigen binds directly to the large subunit of purified DNA polymerase alpha. EMBO J 9: 3329–3336

    CAS  PubMed  Google Scholar 

  • Eggerding FA, Pierce WC (1986) Molecular biology of adenovirus type 2 semipermissive infections. I. Viral growth and expression of viral replicative functions during restricted adenovirus infection. Virology 148: 97–113

    Article  CAS  PubMed  Google Scholar 

  • Esche H, Schilling R, Doerfler W (1979) In vitro translation of adenovirus type 12-specific mRNA isolated from infected and transformed cells. J Virol 30: 21–31

    CAS  PubMed  Google Scholar 

  • Fanning E, Schneider J, Arthur A, Höss A, Moarefi I, Modrow S (1989) Structure and function of SV40 large T antigen. Curr Top Microbiol Immunol 144: 9–19

    CAS  PubMed  Google Scholar 

  • Faucon N, Desgranges C (1980) Persistence of human adenovirus 5 in human cord blood lympho- blastoid cell lines transformed by Epstein-Barr virus. Infect Immun 29: 1180–1184

    CAS  PubMed  Google Scholar 

  • Fejer G, Berencsi G, Ruzsics A, Belak S, Linne T, Nasz I (1992) Multiple enlargements in the right inverted terminal repeat of the DNA of canine adenovirus type 2. Acta Microbiol Hung 39: 159–168

    CAS  PubMed  Google Scholar 

  • Fox RI, Baum SG (1974) Posttranscriptional block to adenovirus replication in nonpermissive monkey cells. Virology 60: 45–53

    Article  CAS  PubMed  Google Scholar 

  • Gallimore PH (1974) Interactions of adenovirus type 2 with rat embryo cells. Permissiveness, transformation and in vitro characteristics of adenovirus transformed rat embryo cells. J Gen Virol 25: 263–273

    Article  CAS  PubMed  Google Scholar 

  • Gerard RD, Guggenheimer RA, Gluzman Y (1987) Analysis of nonpermissivity in mouse cells overexpressing simian virus 40 T antigen. J Virol 61: 851–857

    CAS  PubMed  Google Scholar 

  • Gil G, Smith JR, Goldstein JL, Slaughter CA, Orth K, Brown MS, Osborne TF (1988) Multiple genes encode nuclear factor 1-like proteins that bind to the promoter for 3-hydroxy-3-methylglutaryl- coenzyme A reductase. Proc Natl Acad Sci USA 85: 8963–8967

    Article  CAS  PubMed  Google Scholar 

  • Grand RJA (1987) The structure and functions of the adenovirus early region 1 proteins. Biochem J 241 : 25–38

    CAS  PubMed  Google Scholar 

  • Groff DE, Daniell E (1981) Early RNA of adenovirus type 3 in permissive and abortive infections. J Virol 40: 620–624

    CAS  PubMed  Google Scholar 

  • Haj-Ahmad Y, Graham FL (1986) Characterization of an adenovirus type 5 mutant carrying embedded inverted terminal repeats. Virology 153: 22–34

    Article  CAS  PubMed  Google Scholar 

  • Hammarskjold M-L, Winberg G (1980) Encapsidation of adenovirus 16 DNA is directed by a small DNA sequence at the left end of the genome. Cell 20: 787–795

    Article  CAS  PubMed  Google Scholar 

  • Hashimoto S, Sakakibara N, Kumai H, Nakai M, Sakuma S, Chiba S, Fujinaga K (1991) Fastidious human adenovirus type 40 can propagate efficiently and produce plaques on a human cell line, A549, derived from lung carcinoma. J Virol 65: 2429–2435

    CAS  PubMed  Google Scholar 

  • Hatfield L, Hearing P (1991) Redundant elements in the adenovirus type 5 inverted terminal repeat promote bidirectional transcription in vitro and are important for virus growth in vivo. Virology 184: 265–276

    Article  CAS  PubMed  Google Scholar 

  • Hatfield L, Hearing P (1993) The NFIII/OCT-1 binding site stimulates adenovirus DNA replication in vivo and is functionally redundant with adjacent sequences. J Virol 67: 3931–3939

    CAS  PubMed  Google Scholar 

  • Herrmann CH, Mathews MB (1989) The adenovirus E1B 19-kilodalton protein stimulates gene expression by increasing DNA levels. Mol Cell Biol 9: 5412–5423

    CAS  PubMed  Google Scholar 

  • Hogenkamp T, Esche H (1990) Nucleotide sequence of the right 10% of adenovirus type 12 DNA encoding the entire region E4. Nucleic Acids Res 18: 3065–3066

    Article  CAS  PubMed  Google Scholar 

  • Horvath J, Weber JM (1988) Nonpermissivity of human peripheral blood lymphocytes to adenovirus type 2 infection. J Virol 62: 341–345

    CAS  PubMed  Google Scholar 

  • Horvath J, Palkonyay L, Weber J (1986) Group C adenovirus DNA sequences in human lymphoid cells. J Virol 59: 189–192

    CAS  PubMed  Google Scholar 

  • Hsir K-HL, Lübeck MD, Davis AR, Bhat RA, Selling BH, Bhat BM, Mizutani S, Murphy BR, Collins PL, Chanock RM, Hung PP (1992) Immunogenicity of recombinant adenovirus-respiratory syncytial virus vaccines with adenovirus types 4, 5, and 7 vectors in dogs and a chimpanzee. J Infect Dis 166:769–775

    Article  Google Scholar 

  • Ishibashi M, Yasue H (1984) Adenoviruses of animals. In: Ginsberg HS (ed) The adenoviruses. Plenum, New York, pp 497–562

    Google Scholar 

  • Ishibashi S, Brown MS, Goldstein JL, Gerard RD, Hammer RE, Herz J (1993) Hypercholesterolemia in low density lipoprotein receptor knockout mice and reversal by adenovirus-mediated gene delivery. J Clin Invest 92: 883–893

    Article  CAS  PubMed  Google Scholar 

  • Jansen-Durr P, Mondesert G, Kedinger C (1989) Replication-dependent activation of the adenovirus major late promoter is mediated by the increased binding of a transcription factor to sequences in the first intron. J Virol 63: 5124–5132

    CAS  PubMed  Google Scholar 

  • Johnston JM, Anderson KP, Klessig DF (1985) Partial block to transcription of human adenovirus type 2 late genes in abortively infected monkey cells. J Virol 56: 378–385

    CAS  PubMed  Google Scholar 

  • Jüttermann R, Weyer U, Doerfler W (1989) Defect of adenovirus type 12 replication in hamster cells: absence of transcription of viral virus-associated and L1 RNAs. J Virol 63: 3535–3540

    PubMed  Google Scholar 

  • Kirshenbaum LA, MacLellan WR, Mazur W, French BA, Schneider MD (1993) Highly efficient gene transfer into adult ventricular myocytes by recombinant adenovirus. J Clin Invest 92: 381–387

    Article  CAS  PubMed  Google Scholar 

  • Klein H, Maltzman W, Levine AJ (1979) Structure-function relationships of the adenovirus DNA-binding domain. J Biol Chem 254: 11051–11060

    CAS  PubMed  Google Scholar 

  • Klessig DF (1984) Adenovirus-simian virus 40 interactions. In: Ginsberg HS (ed) The adenoviruses. Plenum, New York, pp 399–449

    Google Scholar 

  • Klessig DF, Grodzicker T (1979) Mutations that allow human Ad2 and Ad5 to express late genes in monkey cells map in the viral gene encoding the 72K DNA binding protein. Cell 17: 957–966

    Article  CAS  PubMed  Google Scholar 

  • Klimkait T, Doerfler W (1985) Adenovirus types 2 and 5 functions elicit replication and late expression of adenovirus type 12 DNA in hamster cells. J Virol 55: 466–474

    CAS  PubMed  Google Scholar 

  • Klimkait T, Doerfler W (1987) E1B functions of type C adenoviruses play a role in the complementation of blocked adenovirus type 12 DNA replication and late gene transcription in hamster cells. Virology 161: 109–120

    Article  CAS  PubMed  Google Scholar 

  • Kohtz DS, Cole F, Wong M-L, Hsu M-T (1991) Infection and inhibition of differentiation of human fetal skeletal myoblasts by adenovirus. Virology 184: 569–579

    Article  CAS  PubMed  Google Scholar 

  • Koikeda S, Ibuki R, Sawada Y, Nagata K, Shibata H, Masamune Y, Nakanishi Y (1990) Nuclear factor I stimulates transcription of the adenovirus 12 E1 a gene in a cell-free system. Biochim Biophys Acta 1048: 85–92

    CAS  PubMed  Google Scholar 

  • Kruczek I, Schwarz E, zur Hausen H (1981) Mutants of adenovirus type 12 after adaptation to growth in tumor cell lines. II. Reproducible acquisition of additional sequences after adaptation to a human cervical cancer line. Int J Cancer 27: 139–143

    Article  CAS  PubMed  Google Scholar 

  • Kruijer W, van Schaik FMA, Sussenbach JS (1981) Structure and organization of the gene coding for the DNA binding protein of adenovirus type 5. Nucleic Acids Res 9: 4439–4457

    Article  CAS  PubMed  Google Scholar 

  • Larsen P, Tibbetts C (1985) Spontaneous reiterations of DNA sequences near the ends of adenovirus type 3 genomes. Virology 147: 187–200

    Article  CAS  PubMed  Google Scholar 

  • Lavery D, Fu SM, Lufkin T, Chen-Kiang S (1987) Productive infection of cultured human lymphoid cells by adenovirus. J Virol 61: 1466–1472

    CAS  PubMed  Google Scholar 

  • Lazaridis I, Babich A, Nevins JR (1988) Role of the adenovirus 72-kDa DNA binding protein in the rapid decay of early viral mRNA. Virology 165: 438–445

    Article  CAS  PubMed  Google Scholar 

  • Ledinko N, Fong CKY (1969) Kinetics of nucleic acid synthesis in human embryonic kidney cultures infected with adenovirus 2 or 12: inhibition of cellular deoxyribonucleic acid synthesis. J Virol 4: 123–132

    CAS  PubMed  Google Scholar 

  • Leppard KN, Shenk T (1989) The adenovirus E1 B 55kd protein influences mRNA transport via an intranuclear effect on RNA metabolism. EMBO J 8: 2329–2336

    CAS  PubMed  Google Scholar 

  • Lucher LA (1990) Adenovirus type 12 tumor antigen synthesis differs during infection of permissive and non-permissive cells. J Gen Virol 71: 579–583

    Article  CAS  PubMed  Google Scholar 

  • Lucher LA, Symington JS, Green M (1986) Biosynthesis and properties of the adenovirus 2 L1 -encoded 52,000- and 55,000-Mr proteins. J Virol 57: 839–847

    CAS  PubMed  Google Scholar 

  • Lucher LA, Khuntirat B, Zhao J, Angeletti PC (1992) Altered expression of adenovirus 12 DNA-binding protein but not DNA polymerase during abortive infection of hamster cells. Virology 189: 187–195

    Article  CAS  PubMed  Google Scholar 

  • Markowitz R-B, Schneringer J, Tolbert S, Küppers A, Dynan WS (1989) Functional organization of the BK virus transcriptional control region. In: Villareal LP (ed) Common mechanisms of transformation by small DNA tumor viruses. American Society for Microbiology, Washington DC, pp 191–205

    Google Scholar 

  • Mathews MB (1990) Control of translation in adenovirus-infected cells. Enzyme 44: 250–264

    CAS  PubMed  Google Scholar 

  • Matsumoto K, Nagata K, Ui M, Hanaoka F (1993) Template activating factor 1, a novel host factor required to stimulate the adenovirus core DNA replication. J Biol Chem 268: 10582–10587

    CAS  PubMed  Google Scholar 

  • Mautner V, MacKay N, Steinthorsdottir V (1989) Complementation of enteric adenovirus type 40 for lytic growth in tissue culture by E1 b 55K function of adenovirus types 5 and 12. Virology 171: 619–622

    Article  CAS  PubMed  Google Scholar 

  • Mautner V, MacKay N, Morris K (1990) Enteric adenovirus type 40: expression of E1B mRNA and proteins in permissive and non-permissive cells. Virology 179: 129–138

    Article  CAS  PubMed  Google Scholar 

  • Mondesert G, Tribouley C, Kedinger C (1992) Identification of a novel downstream binding protein implicated in late-phase-specific activation of the adenovirus major late promoter. Nucleic Acids Res 20: 3881–3889

    Article  CAS  PubMed  Google Scholar 

  • Natuk RJ, Chanda PK, Lübeck MD, Davis AR, Wilhelm J, Hjorth R, Wade MS, Bhat BM, Mizutani S, Lee S, Eichberg J, Gallo RC, Hung PP, Robert-Guroff M (1992) Adenovirus-human immunodeficiency virus (HIV) envelope recombinant vaccines elicit high-titered HIV-neutralizing antibodies in the dog model. Proc Natl Acad Sci USA 89: 7777–7781

    Article  CAS  PubMed  Google Scholar 

  • Oberleithner H, Westphale H-J, Gassner B (1991) Alkaline stress transforms Madin-Darby canine kidney cells. Pflugers Arch 419: 418–420

    Article  CAS  PubMed  Google Scholar 

  • Opalka B, Reith-Witowski M, Roy A, Gnauck J, Schulte-Holthausen H (1992) The transformation- defective adenovirus 12 host range mutant CS-1 lacks the E1 A-specific 9.5S mRNA and contains a second deletion in E1 B. Intervirology 33: 211–216

    CAS  PubMed  Google Scholar 

  • Oraveerakul K, Choi C-S, Molitor TW (1992) Restriction of porcine parvovirus replication in non- permissive cells. J Virol 66: 715–722

    CAS  PubMed  Google Scholar 

  • Ortin J, Scheidtmann K-H, Greenberg R, Westphal M, Doerfler W (1976) Transcription of the genome of adenovirus type 12. III. Maps of stable RNA from productively infected human cells and abortively infected and transformed hamster cells. J Virol 20: 355–372

    CAS  PubMed  Google Scholar 

  • Paonessa G, Gounari F, Frank R, Cortese R (1988) Purification of a NFI-like DNA-binding protein from rat liver and cloning of the corresponding cDNA. EMBO J 7: 3115–3123

    CAS  PubMed  Google Scholar 

  • Persson H, Philipson L (1982) Regulation of adenovirus gene expression. Curr Top Microbiol Immunol 97: 157–203

    Article  CAS  PubMed  Google Scholar 

  • Phelps WC, Yee CL, Münger K, Howley PM (1988) The human papillomavirus type 16 E7 gene encodes transactivation and transformation functions similar to those of adenovirus E1A. Cell 53: 539–547

    Article  CAS  PubMed  Google Scholar 

  • Philipson L (1983) Structure and assembly of adenoviruses. Curr Top Microbiol Immunol 109: 1–52

    Article  CAS  Google Scholar 

  • Pieniazek D, Pieniazek N, Macejak D, Coward J, Rayfield M, Luftig RB (1990a) Differential growth of human enteric adenovirus 41 (TAK) in continuous cell lines. Virology 174: 239–249

    Article  CAS  PubMed  Google Scholar 

  • Pieniazek D, Pieniazek NJ, Macejak D, Luftig R (1990b) Enteric adenovirus 41 (Tak) requires low serum for growth in human primary cells. Virology 178: 72–80

    Article  CAS  PubMed  Google Scholar 

  • Quinlan MP, Klessig DF (1982) Normal translation of human adenovirus in cell-free lysates prepared from abortively as well as productively infected monkey cells. J Virol 44: 426–430

    CAS  PubMed  Google Scholar 

  • Raska K Jr, Strohl WA (1972) The response of BHK21 cells to infection with type 12 adenovirus. VI. Synthesis of virus-specific RNA. Virology 47: 734–742

    Article  CAS  PubMed  Google Scholar 

  • Rowe DT, Graham FL (1981) Complementation of adenovirus type 5 host range mutants by adenovirus type 12 in coinfected HeLa and BHK21 cells. J Virol 38: 191–197

    CAS  PubMed  Google Scholar 

  • Rowe DT, Branton PE, Yee S-P, Bacchetti S, Graham FL (1984) Establishment and characterization of hamster cell lines transformed by restriction endonuclease fragments of adenovirus 5. J Virol 49: 162–170

    CAS  PubMed  Google Scholar 

  • Rubin AL, Ellison BJ (1991) Induction of transformation in NIH3T3 cells by moderate growth constraint: evidence that neoplasia is driven by adaptational change. Carcinogenesis 12: 1801–1806

    Article  CAS  PubMed  Google Scholar 

  • Salewski E, Werner G, Opalka B, Schwarz E, Schulte-Holthausen H (1989) Genome structure of adenovirus 12 host range mutants adapted to growth in simian Vero cells. Intervirology 30: 44–51

    CAS  PubMed  Google Scholar 

  • Santoro C, Mermod N, Andrews PC, Tjian R (1988) A family of human CCAAT-box-binding proteins active in transcription and DNA replication: cloning and expression of multiple cDNAs. Nature 334: 218–224

    Article  CAS  PubMed  Google Scholar 

  • Sawada Y, Raska K Jr, Shenk T (1988) Adenovirus type 5 and adenovirus type 12 recombinant viruses containing heterologous E1 genes are viable, transform rat cells, but are not tumorigenic in rats. Virology 166: 281–284

    Article  CAS  PubMed  Google Scholar 

  • Schaack J, Shenk T (1989) Adenovirus terminal protein mediates efficient and timely activation of viral transcription. Curr Top Microbiol Immunol 144: 185–190

    CAS  PubMed  Google Scholar 

  • Schranz V, Kulcsar G, Dan P, Horvath J, Nasz I, Barinsky IF, Ugryumov EP (1979) Interaction of human lymphocytes and viruses in vitro. Acta Microbiol Acad Sci Hung 26: 1–9

    CAS  PubMed  Google Scholar 

  • Schwarz E, Reinke C, Yamamoto N, zur Hausen H (1982) Terminal rearrangements in the genome of adenovirus type 12 mutants adapted to growth in two human cell lines. Virology 116: 284–296

    Article  CAS  PubMed  Google Scholar 

  • Seiberg M, Aloni Y, Levine AJ (1989a) The adenovirus type 2 DNA-binding protein interacts with the major late promoter attenuated RNA. J Virol 63: 1134–1141

    CAS  PubMed  Google Scholar 

  • Seiberg M, Aloni Y, Levine AJ (1989b) Comparison of human and monkey cells for the ability to attenuate transcripts that begin at the adenovirus major late promoter. J Virol 63: 4093–4096

    CAS  PubMed  Google Scholar 

  • Seth P, Fitzgerald D, Willingham M, Pastan I (1986) Pathway of adenovirus entry into cells. In: Crowell RL, Lonberg-Holm K (eds) Virus attachment and entry into cells. American Society for Microbiology, Washington DC, pp 191–195

    Google Scholar 

  • Shenk T, Flint J (1991) Transcriptional and transforming activities of the adenovirus E1A proteins. Adv Cancer Res 57: 47–85

    Article  CAS  PubMed  Google Scholar 

  • Shibata H, Zheng J-H, Koikeda S, Masamune Y, Nakanishi Y (1989) Cis- and trans-acting factors for transcription of the adenovirus 12 E1A gene. Biochim Biophys Acta 1007: 184–191

    CAS  PubMed  Google Scholar 

  • Shimojo H, Yamashita T (1968) Induction of DNA synthesis by adenoviruses in contact-inhibited hamster cells. Virology 36: 422–433

    Article  CAS  PubMed  Google Scholar 

  • Shiroki K, Ohshima K, Fukui Y, Ariga H (1986) The adenovirus type 12 early-region 1B 58,000-Mr gene product is required for viral DNA synthesis and for initiation of cell transformation. J Virol 57: 792–801

    CAS  PubMed  Google Scholar 

  • Silver L, Anderson CW (1988) Interaction of human adenovirus serotype 2 with human lymphoid cells. Virology 165: 377–387

    Article  CAS  PubMed  Google Scholar 

  • Silverman L, Klessig DL (1989) Characterization of the translational defect to fiber synthesis in monkey cells abortively infected with human adenovirus: role of ancillary leaders. J Virol 63: 4376–4385

    CAS  PubMed  Google Scholar 

  • Silverman L, Cleghon V, Klessig DF (1989) Increased permissivity of monkey cells to human adenovirus multiplication is affected by culturing conditions and correlates with both synthesis of virion fiber protein and altered splicing of its mRNA. Virology 173: 109–119

    Article  CAS  PubMed  Google Scholar 

  • Spindler KR, Eng CY, Berk AJ (1985) An adenovirus early region 1A protein is required for maximal viral DNA replication in growth-arrested human cells. J Virol 53: 742–750

    CAS  PubMed  Google Scholar 

  • Sprengel J, Schmitz B, Heuss-Neitzel D, Zock C, Doerfler W (1994) The nucleotide sequence of human adenovirus type 12 DNA: a comparative functional evaluation. J Virol 68: 379–389

    CAS  PubMed  Google Scholar 

  • Stabel S, Argos P, Philipson L (1985) The release of growth arrest by microinjection of adenovirus E1A DNA. EMBO J 4: 2329–2336

    CAS  PubMed  Google Scholar 

  • Starzinski-Powitz A, Schultz M, Esche H, Mukai N, Doerfler W (1982) The adenovirus type 12-mouse cell system: permissivity and analysis of integration patterns of viral DNA in tumor cells. EMBO J 1: 493–497

    CAS  PubMed  Google Scholar 

  • Stillman B (1989) Initiation of eukaryotic DNA replication in vitro. Annu Rev Cell Biol 5: 197–245

    Article  CAS  PubMed  Google Scholar 

  • Straus SE (1984) Adenovirus infections in humans. In: Ginsberg HS (ed) The adenoviruses. Plenum, New York, pp 451–496

    Google Scholar 

  • Strohl WA (1973) Alterations in hamster cell regulatory mechanisms resulting from abortive infection with an oncogenic adenovirus. Prog Exp Tumor Res 18: 199–239

    CAS  PubMed  Google Scholar 

  • Subramanian T, Kuppuswamy M, Gysbers J, Mak S, Chinnadurai G (1984) 19-kDa tumor antigen coded by early region E1 b of adenovirus 2 is required for efficient synthesis and for protection of viral DNA. J Biol Chem 259: 11777–11783

    CAS  PubMed  Google Scholar 

  • Svensson U, Persson R, Everitt E (1981) Virus-receptor interaction in the adenovirus system. I. Identification of virion attachment proteins of the HeLa cell plasma membrane. J Virol 38: 70–81

    CAS  PubMed  Google Scholar 

  • Symington JS, Lucher LA, Brackmann KH, Virtanen A, Pettersson U, Green M (1986) Biosynthesis of adenovirus type 2 i-leader protein. J Virol 57: 848–856

    CAS  PubMed  Google Scholar 

  • Tate VE, Philipson L (1979) Parental adenovirus DNA accumulates in nucleosome-like structures in infected cells. Nucleic Acids Res 6: 2769–2785

    Article  CAS  PubMed  Google Scholar 

  • Temperely SM, Hay RT (1992) Recognition of the adenovirus type 2 origin of DNA replication by the virally encoded DNA polymerase and preterminal proteins. EMBO J 11: 761–768

    Google Scholar 

  • Thomas PG, Mathews MG (1980) DNA replication and the early to late transition in adenovirus infection. Cell 22: 523–533

    Article  CAS  PubMed  Google Scholar 

  • Tibbetts C (1977) Viral DNA sequences from incomplete particles of human adenovirus type 7. Cell 17: 243–249

    Article  Google Scholar 

  • Tiemessen CT, Ujfalusi M, Kidd AH (1993) Subgroup F adenovirus growth in fetal intestinal organ ćultures. Arch Virol 132: 193–200

    Article  CAS  PubMed  Google Scholar 

  • Van Ormondt H, Galibert F (1984) Nucleotide sequences of adenovirus DNAs. Curr Top Microbiol Immunol 110: 73–142

    PubMed  Google Scholar 

  • Villareal LP, Fan H (1989) History and biological strategy of polyomavirus, adenovirus, and papillomavirus. In: Villareal LP (ed) Common mechanisms of transformation by small DNA tumor viruses. American Society for Microbiology, Washington DC, pp 1–17

    Google Scholar 

  • Weber J, Mak S (1970) Multiplication of adenovirus in heterokaryocytes produced by fusion of infected permissive and nonpermissive cells. Virology 42: 540–543

    Article  CAS  PubMed  Google Scholar 

  • Weber J, Mak S (1972) Synthesis of viral components in hybrids of differentially permissive cells infected with adenovirus type 12. Exp Cell Res 74: 423–429

    Article  CAS  PubMed  Google Scholar 

  • Werner G, zur Hausen H (1978) Deletions and insertions in adenovirus type 12 DNA after viral replication in Vero cells. Virology 86: 66–77

    Article  CAS  PubMed  Google Scholar 

  • Weyer U, Doerfler W (1985) Species dependence of the major late promoter in adenovirus type 12 DNA. EMBO J 4: 3015–3019

    CAS  PubMed  Google Scholar 

  • White DO, Fenner FJ (1986) Medical virology, 3rd edn. Academic, Orlando, pp 389–400

    Google Scholar 

  • Wickham TJ, Mathias P, Cheresh DA, Namerow GR (1993) Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachment. Cell 73: 309–319

    Article  CAS  PubMed  Google Scholar 

  • Williams JF (1986) Adenovirus genetics. In: Doerfler W (ed) Adenovirus DNA. Martinus Nijhoff, Boston, pp 247–309

    Google Scholar 

  • Wold WSM, Gooding LR (1991) Region E3 of adenovirus: a cassette of genes involved in host immunosurveillance and virus-cell interactions. Virology 184: 1–8

    Article  CAS  PubMed  Google Scholar 

  • Yamashita T, Moritsugu Y, Shimojo H (1971) Suppression of cellular DNA synthesis in growing cells by ultraviolet-irradiated adenoviruses. Virology 45: 687–696

    Article  CAS  PubMed  Google Scholar 

  • Yamazaki Y, Shimada Y, Shibata-Sakurai H, Masamune Y, Nakanishi Y (1992) Multiple cis-acting elements that regulate transcription of the adenovirus 12 E1A gene. Virus Genes 6: 261–271

    Article  CAS  PubMed  Google Scholar 

  • Yee CL, Krishnan-Hewlett I, Baker CC, Schlegel R, Howley PM (1985) Presence and expression of human papillomavirus sequences in human cervical cell lines. Am J Pathol 119: 3261–3266

    Google Scholar 

  • Yin FH, Lomax NB (1983) Host range mutants of human rhinovirus in which nonstructural proteins are altered. J Virol 48: 410–418

    CAS  PubMed  Google Scholar 

  • Zabner J, Couture LA, Gregory RJ, Graham SM, Smith AE, Welsh MJ (1993) Adenovirus-mediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis. Cell 75: 207–216

    Article  CAS  PubMed  Google Scholar 

  • Zhang S, Mak S, Branton PE (1992) Adenovirus type 12 early region 1B proteins and metabolism of early viral mRNAs. Virology 191: 793–802

    Article  CAS  PubMed  Google Scholar 

  • Zock C, Doerfler W (1990) A mitigator sequence in the downstream region of the major late promoter of adenovirus type 12 DNA. EMBO J 9: 1615–1623

    CAS  PubMed  Google Scholar 

  • Zock C, Iselt A, Doerfler W (1993) A unique mitigator sequence determines the species specificity of the major late promoter in adenovirus type 12 DNA. J Virol 67: 682–693

    CAS  PubMed  Google Scholar 

  • Zorn GA, Anderson CW (1981) Adenovirus type 2 expresses fiber in monkey-human hybrids and reconstructed cells. J Virol 37: 759–769

    CAS  PubMed  Google Scholar 

  • Zucker ML, Flint SJ (1985) Infection and transformation of mouse cells by human adenovirus type 2. Virology 147: 126–141

    Article  CAS  PubMed  Google Scholar 

  • zur Hausen H, Sokol F (1969) Fate of adenovirus type 12 genomes in nonpermissive cells. J Virol 4: 256–263

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Biological Sciences, Illinois State, University, Normal, IL, 61761, USA

    L. A. Lucher

Authors
  1. L. A. Lucher
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Institut für Genetik, Universität zu Köln, Weyertal 121, 50931, Köln, Germany

    Walter Doerfler  & Petra Böhm  & 

Rights and permissions

Reprints and permissions

Copyright information

© 1995 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Lucher, L.A. (1995). Abortive Adenovirus Infection and Host Range Determinants. In: Doerfler, W., Böhm, P. (eds) The Molecular Repertoire of Adenoviruses I. Current Topics in 199/I Microbiology and Immunology, vol 199/1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79496-4_8

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-79496-4_8

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-79498-8

  • Online ISBN: 978-3-642-79496-4

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation