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Review of Known Prognostic Variables

  • Conference paper
Adjuvant Therapy of Breast Cancer V

Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 140))

Abstract

Prognostic variables should be used to provide an estimate of recurrence and death in patients with primary breast cancer. Evaluation of prognostic variables have to consider two different aims:

  1. 1.

    Use as a prognostic factor, describing groups of low and high risk for recurrence and death. Maximum information is obtained if the favorable group shows an overall survival of approximately 90%–100%, because these patients do not require further adjuvant treatment.

  2. 2.

    Use as a predictive factor, describing the responsiveness of endocrine or cytotoxic therapy or both. Treatment could be intensified in patients at high risk and known responsiveness or omitted in patients with known drug resistance.

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Author information

Authors and Affiliations

  1. Department of Gynecology and Oncology, Johann Wolfgang Goethe — University, Theodor-Stern-Kai 7, 60590, Frankfurt/Main, Germany

    M. Kaufmann

Authors
  1. M. Kaufmann
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Editor information

Editors and Affiliations

  1. Department of Medicine C, Kantonsspital, CH-9007, St. Gallen, Switzerland

    Hans Jörg Senn  & Beat Thürlimann  & 

  2. Division of Biostatistics, Dana Farber Cancer Institute, 44, Binney Street, 02115, Boston, MA, USA

    Richard D. Gelber Ph.D.

  3. Ospedale Civico, CH-6900, Lugano, Switzerland

    Aron Goldhirsch

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© 1996 Springer-Verlag Berlin Heidelberg

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Kaufmann, M. (1996). Review of Known Prognostic Variables. In: Senn, H.J., Gelber, R.D., Goldhirsch, A., Thürlimann, B. (eds) Adjuvant Therapy of Breast Cancer V. Recent Results in Cancer Research, vol 140. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79278-6_10

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  • DOI: https://doi.org/10.1007/978-3-642-79278-6_10

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-79280-9

  • Online ISBN: 978-3-642-79278-6

  • eBook Packages: Springer Book Archive

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