Abstract
Chromosomal mosaicism, the presence of two or more distinct cell lines containing different karyotypes in one individual, originates during postzygotic development through nondisjunction, anaphase lag or, less commonly, through structural rearrangement. In large, consecutive live-born studies, the incidence of chromosomal mosaicism has been established as less than one in 1000 (Friedrich and Nielsen 1973; Jacobs et al. 1974; Hamerton et al. 1975). As in these studies the existence and frequency of chromosomal mosaicism were of no major concern, the small number of cells analysed in individual cases is the most likely explanation of the low incidence reported.
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© 1985 Springer-Verlag Berlin Heidelberg
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Kalousek, D.K. (1985). Mosaicism Confined to Chorionic Tissue in Human Gestations. In: Fraccaro, M., Simoni, G., Brambati, B. (eds) First Trimester Fetal Diagnosis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70707-0_20
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DOI: https://doi.org/10.1007/978-3-642-70707-0_20
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