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Revisiting Lactate in Critical Illness

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Annual Update in Intensive Care and Emergency Medicine 2013

Part of the book series: Annual Update in Intensive Care and Emergency Medicine ((AUICEM))

Abstract

The traditional view of lactate as a harmful waste product of anaerobic glycolysis needs to be challenged in the face of new evidence. It is important to differentiate between lactate as a biomarker on one hand and lactate as a metabolic substrate on the other. Here we will review metabolic, protective and potential therapeutic properties of this fascinating molecule.

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Acknowledgement

We dedicate this chapter to the memory of our friend Professor Xavier M Leverve.

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Authors and Affiliations

  1. Department of Intensive Care Medicine, Nepean Hospital & Nepean Medical School, University of Sydney, 63, 2750, Penrith, NSW, Australia

    M. Nalos, A. S. McLean & S. Huang

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  1. M. Nalos
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  2. A. S. McLean
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  3. S. Huang
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Correspondence to M. Nalos .

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Editors and Affiliations

  1. Erasme Hospital, Université libre de Bruxelles, Brussels, Belgium

    Jean-Louis Vincent Prof.

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Nalos, M., McLean, A.S., Huang, S. (2013). Revisiting Lactate in Critical Illness. In: Vincent, JL. (eds) Annual Update in Intensive Care and Emergency Medicine 2013. Annual Update in Intensive Care and Emergency Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-35109-9_34

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  • DOI: https://doi.org/10.1007/978-3-642-35109-9_34

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-35108-2

  • Online ISBN: 978-3-642-35109-9

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